作者： Zhi Zhang;Fang Wang;Bing-jian Wang;Guang Chu;Qunan Cao;Bao-Gui Sun and Qiu-Yan Dai （a Department of Cardiology, School of Medicine, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China; b Department of Cardiology, Huai’an First People’s Hospital, Nanjing Medical University, Jiangsu Province, 223300, China）

出处： Journal of Molecular Endocrinology 2014 Vol.53 No.2 P145-154

关键词： 3D vessel model;Adiponectin;Extracellular matrix remodelling;Hypertension;Leptin;Obesity

摘要： Vascular extracellular matrix (ECM) remodelling, which is the result of disruption in the balance of ECM synthesis and degradation, induces vessel fib ...

作者： Qi, Baozhen;Wei, Yong;Chen, Songwen;Zhou, Genqing;Li, Hongli;Xu, Juan;Ding, Yu;Lu, Xiaofeng;Zhao, Liqun;Zhang, Feng;Chen, Gang;Zhao, Jing;Liu, Shaowen （Department of Cardiology, Shanghai First People\'s Hospital, Shanghai Jiaotong University, 100, Haining Road, Hongkou District, Shanghai 200080, China Wolfson Institute for Biomedical Research, University College London, Cruciform Building, Gower Street, London WC1E 6BT, United Kingdom）

出处： CARDIOVASCULAR RESEARCH 2014 Vol.102 No.3 P480-486

关键词： Atrial fibrillation;Ganglionated plexus;SCN10A;Sodium channel;Vagus nerve

摘要： Emerging evidences indicate that SCN10A/Na(V)1.8 is associated with cardiac conduction and atrial fibrillation, but the exact role of Na(V)1.8 in card ...

作者： Yu S;Fisher YL （*Department of Ophthalmology, Vitreous Retina Macula Consultants of New York, New York, New York daggerShanghai Jiao Tong University affiliated Shanghai First People\'s Hospital, Shanghai, China double daggerLuEsther T. Mertz Retinal Research Center, Manhattan Eye Ear and Throat Hospital, New York, New York.）

出处： Retina 2014 Vol.34 No.5

作者： Wu, Z.;Sun, Y.;Mei, X.;Zhang, C.;Pan, W.;Shi, W. （Department of Dermatology, Shanghai First People\'s Hospital Shanghai Jiaotong University, School of Medicine Jiaotong University, No.100, Rd., Haining, Shanghai, China Department of Dermatology, Shanghai Songjiang Jiuting Hospital, Shanghai, China Department of Dermatology, Changzheng Hospital Affiliated to Second Military Medical University, Shanghai, China）

出处： CLINICAL AND EXPERIMENTAL DERMATOLOGY 2014 Vol.39 No.4 P525-532

关键词： CD40 LIGAND;ERYTHEMATOSUS;METHYLTRANSFERASE;EXPRESSION;METHYLATION

摘要： BackgroundSystemic lupus erythematosus (SLE) affects primarily women, and oestrogen appears to play a significant role in SLE development. Our previou ...

作者： Sun F;Han B;Cui D;Zhao F;Sun X;Zhuo J;Jing Y;Liu H;Xia S;Yang Y;Luo G;Guo F. （1 Department of Urology, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, No.100, Haining Road, Shanghai, 200080, China.）

出处： World J Urol 2014

摘要： PURPOSE: To evaluate the long-term durability and complication rates after thulium laser resection of prostate (TmLRP) through a prospective multiple- ...

作者： Aijun Sun,  Yong Cheng,  Yingmei Zhang,  Qian Zhang,  Shijun Wang,  Shan Tian,  Yunzeng Zou,  Kai Hu,  Jun Ren,  Junbo Ge （1 Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China 2 Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China 3 Center for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, WY 82071, USA 4 Heart Centre of Zhengzhou Ninth People\'s Hospital, Zhengzhou, Henan 450000, China 5 Department of Cardiology, Branch of Shanghai First People\'s Hospital, Shanghai 200050, China 6 Department of Rehabilitation, Huashan Hospital, Fudan University, Shanghai 200040, China）

出处： Journal of Molecular and Cellular Cardiology 2014 Vol.71 P92-104

关键词： ALDH2;Dilated cardiomyopathy;Doxorubicin;4-HNE;Autophagy

摘要： Mitochondrial aldehyde dehydrogenase (ALDH2) protects against cardiac injury via reducing production of 4-hydroxynonenal (4-HNE) and ROS. This study w ...

作者： Zhou, Qianjun;Facciponte, John;Jin, Min;Shen, Qiang;Lin, Qiang （Department of Thoracic Surgery, Shanghai First People\'s Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, China Department of Microbiology and Immunology, State University of New York at Buffalo, Buffalo, NY, United States Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and SJTUSM, Shanghai, China Department of Clinical Cancer Prevention, Division of Cancer Prevention and Population Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, United States）

出处： CANCER LETTERS 2014 Vol.344 No.1 P13-19

关键词： Humanized mice;Immunodeficient mice;NOD-SCID-IL2rg[sup]-/-[/sup] mice;Preclinical model;Tumor model;Xenograft

摘要： Humanized mouse models have been developed and utilized in cancer research for decades. Newly developed combined immunodeficient NOD-SCID-IL2rg(-/-) m ...

作者： Zha, Bingbing;Huang, Xiuyan;Lin, Jun;Liu, Jun;Hou, Yingyong;Wu, Guilong （1 Department of Endocrinology, Shanghai Fifth People\'s Hospital, Fudan University, Shanghai P.R. China 2 Department of Surgery, Shanghai Sixth People\'s Hospital, Shanghai Jiaotong University, Shanghai P.R. China 3 Department of Pathology, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai P.R. China 4 Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai P.R. China）

出处： Journal of Clinical Laboratory Analysis 2014 Vol.28 No.3 P249-254

关键词： CD20;CD4;CD8;FoxP3;Graves\' disease;Hashimoto\'s thyroiditis;Regulatory T cells

摘要： Background: The autoimmune thyroid disease (AITD) is an organ-specific autoimmune disease characterized by the breakdown of self-tolerance to thyroid ...

作者： Xueying Ding;Xiaoli Hou;Shouhong Gao;Mingxue Sun;Fengwu Lin;Guojun Cai( caiemperor@163.com);Kai Xiao( kaixiaocn@gmail.com) （1 Department of Pharmacy, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China 2 Laboratory of Toxicology & Pharmacology, Faculty of Tropical Medicine and Public Health, Second Military Medical University, Shanghai, China 3 Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai, China 4 China-Japan Union Hospital of Jilin University, Changchun, China 5 Department of Pharmacology, School of Pharmacy, Second Military Medical University, Shanghai, China）

出处： Pakistan Journal of Pharmaceutical Sciences 2014 Vol.27 No.6 P1931-1937

关键词： POLYGONUM-CUSPIDATUM;INJURY;ABSORPTION

摘要： To investigate the pharmacokinetic and bioavailability of polydatin (PD) in rats after oral and intravenous administration, a simple, rapid and sensit ...

作者： Liu, Haixia;Zheng, Mingrui;Qiao, Jianou;Dang, Yajie;Zhang, Pengyu;Jin, Xianqiao （1 Department of Respiratory Medicine, Shanghai First People\'s Hospital Affiliated Shanghai JiaoTong University School of Medicine, Shanghai China 2 Department of Respiratory Medicine, Shanghai Ninth People\'s Hospital Affiliated Shanghai JiaoTong University School of Medicine, Shanghai China 3 Department of Respiratory Medicine, Huashan Hospital, Fudan University, Shanghai China）

出处： Immunology 2014 Vol.142 No.1 P78-88

关键词： airway responsiveness;Aspergillus fumigatus;asthma;CRTH2;eosinophil;prostaglandin D2;prostaglandin D2

摘要： Aspergillus fumigatus is often associated in asthmatic patients with the exacerbation of asthma symptoms. The pathomechanism of this phenomenon has no ...