作者： Qinghua Zhao;Yongxing Zhang;Guoying Deng;Wenbin Jiang;Linna Zhang;Liqing Di;Yangyang Su;Xiaoyu Du;Xinyuan Wu;Qianzi Che;Keyu Chen （Department of Orthopedics, First People's Hospital, Shanghai Jiao Tong University, Shanghai 200080, China. Email: sawboneszhao@163.com. Department of Orthopedics, First People's Hospital, Shanghai Jiao Tong University, Shanghai 200080, China.）

出处： Zhonghua yi xue za zhi 2014 Vol.94No.48 P3831-3835

摘要： OBJECTIVE: To explore the incidence of four types of chronic pain, i.e. headache, abdominal pain, neck & shoulder pain (NSP) and low back pain (LBP) a ...

作者： Lu Lun‐Gen （1 Department of Gastroenterology, Shanghai First People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China）

出处： Journal of Clinical and Translational Hepatology 2014 Vol.2 No.3 P197-201

关键词： Hepatitis B virus;Chronic HBV infection;Liver cirrhosis;Antiviral therapy

摘要： Hepatitis B virus (HBV) infection is a leading cause of liver disease worldwide, with 75% of those affected distributed in the Asia‐Pacific region. Ap ...

作者： Ye-Jiao Wu;Ming-Yi Xu;Lun-Gen Lu （Department of Gastroenterology, Shanghai First People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China）

出处： Journal of Clinical and Translational Hepatology 2014 Vol.2 No.4 P222–227

关键词： Chronic hepatitis B, Chronic hepatitis C, Liver fibrosis, Disease progression

摘要： Chronic liver diseases, such as chronic hepatitis B (CHB) and chronic hepatitis C (CHC), are characterized by the presence of liver fibrosis, which ma ...

作者： Zhang, Ji-Gang ;Li, Xiao-Yu ;Wang, Yu-Zhu ;Zhang, Qi-Di ;Gu, Sheng-Ying ;Wu, Xin ;Zhu, Guan-Hua ;Li, Qin ;Liu, Gao-Lin （1 Department of Pharmacy, Shanghai First People\'s Hospital, School of medicine, Shanghai Jiao Tong University, Shanghai, P.R. China 2 Department of Gastroenterology, Shanghai First People\'s Hospital, School of medicine, Shanghai Jiao Tong University, Shanghai, P.R. China）

出处： PLoS ONE 2014 Vol.9 No.9 P1-8

关键词： Biology and life sciences;Cell biology;Medicine and health sciences;Oncology;Research Article

摘要： Ras homolog family member A (RhoA) and Rho-associated coiled coil-containing protein kinases 1 and 2 (ROCK1 and 2) are key regulators of focal adhesio ...

作者： Ma, Mingming ;Zhang, Zhengwei ;Du, Ergang ;Zheng, Wenjing ;Gu, Qing ;Xu, Xun ;Ke, Bilian （1 1 Department of Ophthalmology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China 2 2 Shanghai Key Laboratory of Fundus Disease, Shanghai, China 3 3 Jinhua Eye Hospital, Jinhua, Zhejiang, China）

出处： PLoS ONE 2014 Vol.9 No.4 P1-9

关键词： Geriatric ophthalmology;Medicine and health sciences;Ophthalmology;Research Article;Retinal disorders

摘要： Background: The canonical Wnt signaling pathway plays important roles in cellular proliferation and differentiation, axonal outgrowth, cellular mainte ...

作者： Xia, Xin ;Wen, Rong ;Chou, Tsung-Han ;Li, Yiwen ;Wang, Zhengying ;Porciatti, Vittorio （1 Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida, United States of America 2 Department of Ophthalmology, Shanghai First People’s Hospital, Jiaotong University, Shanghai, China 3 Shanghai Key Laboratory for Ocular Fundus Diseases, Shanghai, China）

出处： PLoS ONE 2014 Vol.9 No.9 P1-7

关键词： Eye diseases;Glaucoma;Medicine and health sciences;Ophthalmology;Research Article;Retinal disorders

摘要： Injury to retinal ganglion cell (RGC) axons leads to selective loss of RGCs and vision. Previous studies have shown that exogenous neurotrophic factor ...

作者： Hu, Yanling ;Wan, Rong ;Yu, Ge ;Shen, Jie ;Ni, Jianbo ;Yin, Guojian ;Xing, Miao ;Chen, Congying ;Fan, Yuting ;Xiao, Wenqin ;Xu, Gang ;Wang, Xingpeng ;Hu, Guoyong （1 1 Department of Gastroenterology, Shanghai Tenth People\'s Hospital, Tongji University School of Medicine, Shanghai, China 2 2 Department of Gastroenterology, Shanghai First People\'s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China）

出处： PLoS ONE 2014 Vol.9 No.4 P1-13

关键词： Anatomy;Animal models;Animals;Beta-catenin signaling;Biology and life sciences;Cell biology;Cell death;Cell growth;Cell processes;Cell signaling;Endocrine system;Feedback regulation;Gastroenterology and hepatology;Gene expression;Genetics;Mammals;Mechanisms of signal transduction;Medicine and health sciences;Model organisms;Molecular cell biology;Mouse models;Organisms;Pancreas;Pancreatitis;Rats;Research and analysis methods;Research Article;Rodents;Signal transduction;Signaling cascades;Vertebrates;Wnt signaling cascade

摘要： The role of persistent activation of pancreatic stellate cells (PSCs) in the fibrosis associated with chronic pancreatitis (CP) is increasingly being ...

作者： Zheng, Linfeng ;Sun, Pengpeng ;Zheng, Sujuan ;Han, Yuedong ;Zhang, Guixiang （1 Department of Radiology, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China 2 Department of Radiology, Affiliated Hospital of Binzhou Medical University, Binzhou, Shandong, China 3 Dengfeng People’s Hospital, Zhengzhou, Henan, China 4 Department of Radiology, General Hospital of Lanzhou Military Region, Lanzhou, Gansu, China）

出处： PLoS ONE 2014 Vol.9 No.10 P1-7

关键词： Diagnostic medicine;Diagnostic radiology;Magnetic resonance imaging;Medicine and health sciences;Radiology and imaging;Research Article

摘要： Background: Brain metastasis is a common disease with a poor prognosis. The purpose of this study is to test feasibility and safety of the animal mode ...

作者： Li, Xuguang ;Zhao, Gang ;Ma, Ben ;Li, Rui ;Hong, Jiang ;Liu, Shaowen ;Wang, Dao Wen （1 1 Department of Cardiology, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People\'s Republic of China 2 2 Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People\'s Republic of China）

出处： PLoS ONE 2014 Vol.9 No.4 P1-10

关键词： AKT signaling cascade;Anatomy;Animal models;Biochemistry;Biological tissue;Biology and life sciences;Cardiology;Cardiovascular anatomy;Cell biology;Cell signaling;Cellular types;Diabetic endocrinology;Endocrinology;Endothelial cells;Epithelial cells;Epithelium;Hormones;Insulin;Insulin signaling cascade;Medicine and health sciences;Model organisms;Molecular cell biology;Mouse models;Research and analysis methods;Research Article;Signal transduction;Signaling cascades

摘要： 20-hydroxyeicosatetraenoic acid (20-HETE) induces endothelial dysfunction and is correlated with diabetes. This study was designed to investigate the ...

作者： Ma, Yingyan ;Ying, Xiaohua ;Zou, Haidong ;Xu, Xiaocheng ;Liu, Haiyun ;Bai, Lin ;Xu, Xun ;Zhang, Xi （1 Department of Ophthalmology, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China 2 School of Public Health, Fudan University, Shanghai, China 3 Shanghai Eye Disease Prevention & Treatment Center, Shanghai, China）

出处： PLoS ONE 2014 Vol.9 No.10 P1-8

关键词： Health care;Medicine and health sciences;Ophthalmic procedures;Public and occupational health;Quality of life;Research Article;Socioeconomic aspects of health;Surgical and invasive medical procedures;Vitrectomy;Vitreoretinal surgery

摘要： Background and Purpose: To evaluate the influence of rhegmatogenous retinal detachment (RRD) surgery on elderly patients in terms of visual acuity, vi ...