作者： Xue, Tian;Wei, Nie;Xin, Zhou;Qingyu, Xiu （1 Department of Respiratory Medicine, Shanghai First People\'s Hospital, Shanghai Jiaotong University Shanghai China 2 Department of Respiratory Medicine, Shanghai Changzheng Hospital, Second Military Medical University Shanghai China）

出处： INHALATION TOXICOLOGY 2014 Vol.26 No.1 P14-22

关键词： Angiotensin-converting enzyme 2 (ACE2);chronic obstructive pulmonary disease (COPD);MDA;NF-κB;NF-κB;p38 MAPK;ROS

摘要： Objective: To investigate the anti-inflammatory effects of angiotensin-converting enzyme 2 (ACE2) overexpression on rat model of chronic obstructive p ...

作者： Li Q.;Dong Z.;Zhou F.;Cai X.;Gao Y.;Wang L.-W.; （Department of Oncology, Shanghai First People\'s Hospital Affiliated, Shanghai Jiao Tong University, Shanghai 200080, China Department of Radiotherapy, No.85 Hospital of People\'s Liberation Army, China Department of Oncology, Shanghai East Hospital, Tong Ji University, Shanghai, China）

出处： Cellular Physiology and Biochemistry 2014 Vol.33 No.1 P1-10

关键词： Cell proliferation;KLF5;Sox4;Lung cancer

摘要： Background: Krüppel-like factor 5 (KLF5), a member of zinc finger class of DNA-binding transcriptional regulators, has attracted attention because of ...

作者： Rongfa Chen;Tao Zhang;Liting Kuang;Zhen Chen;Dongzhi Ran;Yang Niu;Kangqing Xu;Huaiyu Gu （Department of Anesthesiology, Peking University Shenzhen Hospital, Shenzhen 518000, China Department of Anesthesiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China Department of Anesthesiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China Department of Anesthesiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, China Department of Rehabilitation, Shanghai First People’s Hospital, Shanghai 201620, China Department of Anesthesiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, China）

出处： BioMed Research International 2014 Vol.2014

作者： Liu, H., Wang, H., Xu, Y., Guo, R., Wen, S., Huang, Y., Liu, W., Shen, M.Email Author, Zhao, J., Zhang, G.Email Author, Shi, X.Email Author View Correspondence (jump link) （a College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, 2999 North Renmin Road, Shanghai 201620, China b Department of Radiology, Shanghai First People\'s Hospital, Shanghai Jiaotong University, 100 Haining Road, Shanghai 200080, China c CQM-Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal）

出处： ACS Applied Materials and Interfaces 2014 Vol.6 No.9 P6944-6953

关键词： Engineering controlled terms;Acetylation;Cell culture;Computerized tomography;Dendrimers;Metal nanoparticles;Nanoprobes;Polyethylene glycols;Tumors;Engineering uncontrolled terms;Asialoglycoprotein receptors;Concentration ranges;CT imaging;Fluorescein isothiocyanate;Gold Nanoparticles;Hepatocellular carcinoma;Lactobionic acid;Polyamidoamine dendrimers;Engineering main heading;Gold;EMTREE drug terms;dendrimer;gold;metal nanoparticle;EMTREE medical terms;animal;chemistry;computer assisted tomography;flow cytometry;human;liver cell carcinoma;liver tumor;metabolism;mouse;radiography;transmission electron microscopy;ultraviolet spectrophotometry;xenograft;MeSH;Animals;Carcinoma, Hepatocellular;Dendrimers;Flow Cytometry;Gold;Heterografts;Humans;Liver Neoplasms;Metal Nanoparticles;Mice;Microscopy, Electron, Transmission;Spectrophotometry, Ultraviolet;Tomography, X-Ray Computed

摘要： Development of novel nanomaterial-based contrast agents for targeted computed tomography (CT) imaging of tumors still remains a great challenge. Here ...

作者： Dong Y.;Wang X.;Wang Y.;Liu Y.;Zhang J.;Qian W.;Wu S. （Department of Obstetrics and Gynecology, Shanghai First People\'s Hospital Affiliated, Shanghai Jiaotong University, No 650, Xinsongjiang Road, Songjiang District, Shanghai, China Department of Obstetrics and Gynecology, Shanghai Tenth People\'s Hospital, Shanghai, China Department of Obstetrics and Gynecology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China）

出处： International Journal of Gynecological Cancer 2014 Vol.24 No.9 P1642-1647

关键词： 18F-FDG PET/CT;Cervical carcinoma;Retrospective;Pathology matched.

摘要： Objective: The aim of this study was to evaluate the validity of 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomograp ...

作者： Zhou, B., Zheng, L., Peng, C., Li, D., Li, J., Wen, S., Shen, M.Email Author, Zhang, G.Email Author, Shi, X.Email Author View Correspondence (jump link) （a College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620, China b Department of Radiology, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai, 200080, China c State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China）

出处： ACS Applied Materials and Interfaces 2014 Vol.6 No.19 P17190-17199

关键词： Engineering controlled terms;Biocompatibility;Biological organs;Blood;Cost effectiveness;Fiber optic sensors;Gold;Image processing;Lakes;Metal nanoparticles;Nanoparticles;Synthesis (chemical);Tumors;Engineering uncontrolled terms;Concentration ranges;CT imaging;Enhanced Permeability and Retention effect;Gold Nanoparticles;Molecular contrast agents;PEgylation;Polyethylenimines;Synthesis and characterizations;Engineering main heading;Computerized tomography;EMTREE drug terms;gold;macrogol derivative;metal nanoparticle;polyethyleneimine;EMTREE medical terms;animal;antibody specificity;Bagg albino mouse;cell death;computer assisted tomography;drug effects;drug screening;female;hemolysis;human;male;neoplasm;nude mouse;particle size;procedures;radiography;radionuclide ventriculography;Sprague Dawley rat;synthesis;tissue distribution;tumor cell line;ultraviolet spectrophotometry;MeSH;Animals;Cell Death;Cell Line, Tumor;Female;Gated Blood-Pool Imaging;Gold;Hemolysis;Humans;Male;Metal Nanoparticles;Mice, Inbred BALB C;Mice, Nude;Neoplasms;Organ Specificity;Particle Size;Polyethylene Glycols;Polyethyleneimine;Rats, Sprague-Dawley;Spectrophotometry, Ultraviolet;Tissue Distribution;Tomography, X-Ray Computed;Xenograft Model Antitumor Assays

摘要： The synthesis and characterization of gold nanoparticles (AuNPs) entrapped within polyethylene glycol (PEG)-modified polyethylenimine (PEI) for blood ...

作者： Zhao, Zhao;Sun, Tao;Jiang, Yun;Wu, Lijiang;Cai, Xiangzhong;Sun, Xiaodong;Sun, Xiangjun （1 College of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China 2 Department of Ophthalmology, Shanghai First People\'s Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, China 3 Eye Research Institute, Shanghai JiaoTong University, Shanghai, China）

出处： Food & Chemical Toxicology 2014 Vol.74 P216-224

关键词： A2E N-retinyledin- N-retinylethanolamin;AMD age-related macular degeneration;Apoptosis;ER stress;Grape skin polyphenols;GSEs grape skin extracts;Photooxidation;RPE;RPE retinal pigmented epithelium

摘要： Blue light induced oxidative damage and ER stress are related to the pathogenesis of age-related macular degeneration (AMD). However, the mechanism of ...

作者： Qu L;Deng B;Zeng Y;Cao Z （Department of General Surgery, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China.;Department of General Surgery, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China.;Department of Gastroenterology, Shanghai First People`s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China.;Department of Gastroenterology, Shanghai First People`s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China.）

出处： Cancer Cell Int 2014 Vol.14

摘要： BACKGROUND: Nkx2.8 (Nk2 homeobox 8) is a novel NK-2 gene family member that has been implicated in the progression of human cancer. Its role in the pr ...

作者： Shuangwen Zhou;Jianping Gao;Xun Xu （Shuangwen Zhou ( Shanghai First People\'s Hospital, Shanghai Jiaotong University) ; Jianping Gao ( School of Medicine, Shanghai Jiaotong University) ; Xun Xu ( Shanghai First People\'s Hospital, Shanghai Jiaotong University)）

出处： Clinical & Experimental Ophthalmology 2014 Vol.42 No.7 P637-649

关键词： anti‐VEGF;central retinal vein occlusion;macular oedema;meta‐analysis

摘要： Background Macular oedema secondary to central retinal vein occlusion is a major cause of vision loss. Intraocuclar anti‐vascular endothelial growth f ...

作者： Hu, Jiong;Li, Ning;Chen, Donghui;Wang, Liwei;Wan, Zhiyong （Department of Oncology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai 200080, China）

出处： Tumor 2014 Vol.34 No.2 P158

摘要： Objective: To evaluate the clinical value of CT or type-B ultrasound image-guided percutaneous core biopsy for diagnosis of pancreatic masses. Methods ...