作者： Lu, Y (Lu, Yi);Li, SY (Li, Shaoyong);Ai, JZ (Ai, Jianzhong);Gessler, DJ (Gessler, Dominic J.);Xu, X (Xu, Xun);Gao, GP (Gao, Guangping) （;[ 1 ] Univ Massachusetts, Sch Med, Gene Therapy Ctr, Worcester, MA USA [ 2 ] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 1, Shanghai 200030, Peoples R China）

出处： MOLECULAR THERAPY 2015 Vol.23 PS233

作者： Peng, X (Peng, Xia);Wang, J (Wang, Juan);Li, XY (Li, Xianyang);Lin, LH (Lin, Lihui);Xie, GG (Xie, Guogang);Cui, ZL (Cui, Zelin);Li, J (Li, Jia);Wang, YP (Wang, Yuping);Li, L (Li, Li) （;[ 1 ] Shanghai Jiao Tong Univ, Coll Med, Shanghai Peoples Hosp 1, Dept Lab Med, Shanghai 200080, Peoples R China）

出处： JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 2015 Vol.11 No.12 P2286-2299

关键词： Anti-Fc epsilon Rl alpha Antibody Fab Fragment;Celastrol;Polymeric Nanomicelles;Mast Cells;Basophils;Allergic Diseases

作者： Wang H;Bao W;Jiang F;Che Q;Chen Z;Wang F;Tong H;Dai C;He X;Liao Y;Liu B;Sun J;Wan X （Department of Obstetrics and Gynecology, Shanghai First People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Center Laboratory of Shanghai First People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.;Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address: wanxp@sjtu.edu.cn.）

出处： Cancer Lett 2015 Vol.360 No.2

摘要： P53 mutation plays a pivotal role in tumorigenesis of endometrial cancer (EC), here we report that the gain-of-function mutant p53-R248Q targets the p ...

作者： Jingtao Peng;Jian Ma;Weiguo Li;Ren Mo;Pingzhao Zhang;Kun Gao;Xiaofeng Jin;Jiantao Xiao;Chenji Wang;Jie Fan （b Department of Urology, Inner Mongolia Autonomous Region Peoples Hospital, 20 Zhaowuda Road, Hohhot 010017, China c State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai 200433, China a Department of Urology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, 100 Haining Road, Shanghai 200080, China）

出处： Cancer Letters 2015 Vol.369 No.1 P167-174

关键词： BAP1;MCRS1;Clear;cell;renal;cell;carcinoma;Chromosome;instability;De-ubiquitination

摘要： Characterization of the exome and genome of carcinoma (ccRCC) by next-generation sequencing identified numerous genetic alternations. BRCA1-associated ...

作者： Chen Chen;Bo Shen;Jia-Jia Xiao;Rong Wu;Sarah Jane Duff Canning;Xiao-Ping Wang （Department of Neurology, Shanghai General Hospital, Shanghai Jiao-Tong University, Shanghai 200080, China）

出处： Chin Med J (Engl) 2015 Vol.128 No.13 P1826-1830

摘要： OBJECTIVE: The objective of this study was to review the research on clinical genetics of Wilson's disease (WD). DATA SOURCES: We searched documents f ...

作者： Li You;Lin Chen;Ling Pan;Wen-sha Gu;Jin-Yu Chen （Department of Endocrinology and Metabolism, Shanghai First People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China）

出处： Biochemical and Biophysical Research Communications 2015 Vol.456 No.2 P598-604

关键词： Zfp467;Sost;Wnt signaling;ADSCs

摘要： Osteoporosis is a metabolic disease in which a disruption of the balance between bone formation by osteoblasts and bone resorption by osteoclasts lead ...

作者： Shige Wang;Kai Li;Yu Chen;Hangrong Chen;Ming Ma;Jingwei Feng;Qinghua Zhao;Jianlin Shi （a State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Ding-Xi Road, Shanghai 200050, PR China b Department of Orthopaedics, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, PR China）

出处： Biomaterials 2015 Vol.39 P206-217

关键词： MoS₂ nanosheets;Controllable;Bottom-up;Photothermal regression;Tumor

摘要： Two-dimensional transition metal dichalcogenides, particularly MoS 2 nanosheets, have been deemed as a novel category of NIR photothermal transducing ...

作者： Han, Xiu-guo;Du, Lin;Qiao, Han;Tu, Bing;Wang, Yu-gang;Qin, An;Dai, Ke-rong;Fan, Qi-ming( chillow@163.com);Tang, Ting-ting( tingtingtang@hotmail.com) （1 Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 Department of Orthopedic Surgery, Shanghai First People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 3 Department of Orthopedic Surgery, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Cancer Lett. 2015 Vol.369 No.2 P405-415

关键词： Akt signaling pathway;CXCR1 silencing;Cisplatin sensitivity;Interleukin-8;Osteosarcoma

摘要： Chemotherapy resistance is a major cause of poor prognoses for osteosarcoma patients. This study aimed to determine whether CXCR1 gene knockdown impro ...

作者： Shuangshuang Zhong;Huijing Yin;Yueling Liao;Feng Yao;Qi Li;Jie Zhang;Huike Jiao;Yongxu Zhao;Dongliang Xu;Shuli Liu;Hongyong Song;Yong Gao;Jingyi Liu;Lina Ma;Zhi Pang;Ruixu Yang;Chengyi Ding;Beibei Sun;Xiaofeng Lin;Xiaofeng Ye （1 Key Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China 3 Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China 4 Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China 5 Department of Oncology, Shanghai First People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 6 Translation Medicine Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China 7 Insitute of Health Science, Shanghai Institute of Biological Science, Chinese Academy of Science, Shanghai, China 8 Department of Oral and Maxillofacial--Head and Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China 9 Department of Oncology, Shanghai East Hospital, Tongji University, Shanghai, China 10 Department of Molecular and Cellular Biochemistry, Markey Cancer Center, University of Kentucky College of Medicine, Lexington, Kentucky）

出处： Cancer Research 2015 Vol.75 No.9 P1801-1814

摘要： GPRC5A is a G-protein--coupled receptor expressed in lung tissue but repressed in most human lung cancers. Studies in Gprc5a -/- mice have establishe ...

作者： Fang Fang;Minyu Gu;Lin Chen;Na Li;Xiaoying Ding;Yongde Peng （Department of Endocrine and Metabolism； Shanghai First People’s Hospital Affiliated to Shanghai Jiao Tong University）

出处： Journal of Diabetes Mellitus 2014 No.1 P54-58

关键词： PCOS;Type 2 Diabetes Mellitus;Metabolic Abnormalities

摘要： Background: Metabolic abnormalities have been widely studied in women with polycystic ovary syndrome (PCOS) and in patients with Type 2 diabetes melli ...