作者： Eduardo I. Cardenas¹;Karlhans Fru Che¹;Jon R. Konradsen²;Aihua Bao³;Anders Lindén⁴CA （1 a Division of Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden; 2 b Division of Clinical Immunology and Allergy, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden;c Center for Allergy Research, Karolinska Institute, Stockholm, Sweden;d Astrid Lindgren Children’s Hospital, Karolinska University Hospital Solna, Stockholm, Sweden; 3 a Division of Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden;e Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P. R. China; 4 a Division of Lung and Airway Research, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden;f Karolinska Severe Copd Center, Department of Respiratory Medicine and Allergy, Karolinska University Hospital Solna, Stockholm, Sweden）

出处： Expert Review of Respiratory Medicine

关键词： Asthma;COPD;IL-26;neutrophils;Th17

摘要： Introduction New targets are needed to enable more accurate diagnosis, monitoring and effective therapy in uncontrolled asthma and chronic obstructiv ...

作者： Jian Feng¹;Huiling Ouyang²;Jing Wang³;Deshen Pan²;Luoyan Sheng²;Chaoliang Xu²;Weihong Lin³;Dingzhong Hu¹;Cheng Chang⁴CA;Deshui Jia²CA （¹Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University , Shanghai, 200030, China;²Laboratory of Cancer Genomics and Biology, Department of Urology, and Department of Thoracic Surgery , Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China;³Department of pediatric surgery, Children’s Hospital of Fudan University, Shanghai , 201102, China;⁴Department of Nuclear Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University , Shanghai, 200030, China）

出处： Carcinogenesis

摘要： Non-small cell lung cancer (NSCLC), accounting for 85% of all lung cancer, is one of the leading causes of cancer-related death worldwide. Previously, ...

作者： Yan‐Qiu Wang;Jia‐Rong Zhang;Shuang‐Di Li;Yin‐Yan He （Yan‐Qiu Wang ( Department of Obstetrics and Gynecology, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China) ; Jia‐Rong Zhang ( Department of Obstetrics and Gynecology, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China) ; Shuang‐Di Li ( Department of Obstetrics and Gynecology, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China) ; Yin‐Yan He ( Department of Obstetrics and Gynecology, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China)）

出处： Cancer Science Vol.101 No.7 P1618-1623

摘要： Methylation is an important silencing mechanism of breast and ovarian cancer susceptibility gene 1 (BRCA1) expression in sporadic ovarian cancer. Howe ...

作者： Chaoshuai,Zhao ;Xin,Wang ;Yaqi,Mao ;Ziqian,Xu ;Yue,Sun ;Xingyu,Mei ;Weimin,Shi （Department of Dermatology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. \'(1)\'）

出处： Journal of cosmetic dermatology

关键词： age;gender;skin biophysical parameters;unhealthy styles

摘要： Sweet, spicy or greasy food, staying up late, and using electronic products for a long time are common bad habits nowadays. Their role in skin disease ...

作者： Haitao,Mei ;Yugang,Wen （Shanghai General Hospital, Department of general surgery, Shanghai Jiao Tong University School of Medicine, Shanghai. China. \'(1)\'）

出处： Endocrine, metabolic & immune disorders drug targets

关键词： CRC;Tumorigenesis;combined-biomarkers testing;diagnosis and treatment;liquid biopsy;miRNA

摘要： Colorectal cancer (CRC) is the third most common cancer worldwide, with high morbidity and mortality rates. The diagnosis and treatment of CRC have th ...

作者： Zeyin,Rong ;Zai,Luo ;Jianming,Zhang ;Tengfei,Li ;Zhonglin,Zhu ;Zhilong,Yu ;Zhongmao,Fu ;Zhengjun,Qiu ;Chen,Huang （Department of General Surgery \'(1)\' ; Shanghai General Hospital [2] ; Shanghai Jiaotong University School of Medicine [3] ; Shanghai [4] ; China. [5]）

出处： Cancer science

关键词： GINS4;KLF4;biomarker;colorectal cancer;growth

摘要： GINS complex subunit 4 (GINS4) is essential for DNA replication initiation and elongation in the G 1 /S phase cell cycle in eukaryotes, however, its ...

作者： Yi,Zheng ;Shujun,Xia ;Xinping,Ren ;Weiwei,Zhan ;Zhan,Zheng ;Zhijie,Chen （Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, China. \'(1)\' ; Department of Ultrasound, Shanghai First People\'s Hospital, Shanghai JiaoTong University, Shanghai, China. [2] ; School of Systems Engineering, National University of Defense Technology, Changsha, Hunan, China. [3] ; Shenzhen Mindary Biomedical Electronics Co., Ltd. Shenzhen, Guangdong Sheng, China. [4]）

出处： Clinical hemorheology and microcirculation

关键词： Spleen elastography;chronic hepatitis B;liver fibrosis;shear-wave elastography;transient elastography

摘要： To evaluate the value of spleen shear-wave elastography (sound touch elastography [STE], sound touch quantification [STQ]) in indirect prediction of l ...

作者： Chao Gu;Zhenbo Zhang;Yinhua Yu;Yingtao Liu （Chao Gu ( Obstetrics and Gynecology Hospital, Fudan University, Shanghai) ; Zhenbo Zhang ( Department of Obstetrics and Gynecology, Shanghai First People’s Hospital, Jiao Tong University, Shanghai) ; Yinhua Yu ( Obstetrics and Gynecology Hospital, Fudan University, Shanghai) ; Yingtao Liu ( Obstetrics and Gynecology Hospital, Fudan University, Shanghai)）

出处： Cancer Science Vol.102 No.3 P557-564

摘要： Progestin resistance is the main obstacle to successful conservative therapy in young endometrial cancer patients. To investigate the molecular events ...

作者： Dongli,Li ;Yuanyuan,Gong （Shanghai engineering center for precise diagnosis and treatment of eye diseases，Shanghai. China. \'(1)\' ; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai. China. [2]）

出处： Current stem cell research & therapy

关键词： Exosome;Anterior ischemic optic neuropathy;Mesenchymal stem cellExosome;Anterior ischemic optic neuropathy;Mesenchymal stem cell

摘要： Non-arteritic anterior ischemic optic neuropathy (NAION) is a leading cause of optic nerve-related permanent visual impairment among individuals of ov ...

作者： Karoline K. Barkjohn;Christina Norris;Xiaoxing Cui;Lin Fang;Tongshu Zheng;James J. Schauer;Zhen Li;Yinping Zhang;Marilyn Black;Junfeng (Jim) Zhang;Michael H. Bergin （;Civil and Environmental Engineering, Duke University, Durham, NC, USA;Karoline K. Barkjohn, Civil and Environmental Engineering, Duke University, 121 Hudson Hall, Box 90287, Durham, NC 27708 USA.;Contribution: Conceptualization (lead), Data curation (equal), Formal analysis (lead), ​Investigation (equal), Methodology (lead), Writing - original draft (lead);Civil and Environmental Engineering, Duke University, Durham, NC, USA;Contribution: Conceptualization (supporting), Data curation (equal), ​Investigation (equal), Methodology (supporting), Writing - review &editing (supporting);Nicholas School of the Environment, Duke University, Durham, NC, USA;Contribution: Conceptualization (supporting), ​Investigation (supporting), Writing - review &editing (supporting);School of Architecture, Tsinghua University, Beijing, China;Contribution: ​Investigation (equal), Writing - review &editing (supporting);Civil and Environmental Engineering, Duke University, Durham, NC, USA;Contribution: Data curation (supporting), Formal analysis (supporting);Civil and Environmental Engineering, University of Wisconsin at Madison, Madison, WI, USA;Contribution: Conceptualization (supporting), Funding acquisition (equal), Writing - review &editing (supporting);Shanghai First People’s Hospital, Shanghai Shi, China;Contribution: ​Investigation (supporting), Resources (supporting);School of Architecture, Tsinghua University, Beijing, China;Contribution: Resources (supporting), Writing - review &editing (supporting);Underwriters Laboratories Inc., Marietta, GA, USA;Contribution: Conceptualization (supporting), Funding acquisition (equal);Nicholas School of the Environment, Duke University, Durham, NC, USA;Contribution: Conceptualization (supporting), Funding acquisition (equal), Writing - review &editing (supporting);Civil and Environmental Engineering, Duke University, Durham, NC, USA;Contribution: Conceptualization (supporting), Funding acquisition (lead), Supervision (lead), Writing - review &editing (lead)）

出处： Indoor Air

关键词： air filtration;air sensors;ozone;personal exposure;PM_2.5;portable air cleaner

摘要： Portable air cleaners are increasingly used in polluted areas in an attempt to reduce human exposure; however, there has been limited work characteriz ...