作者： Lu Y.;Xu Y.;Gu Q.;Xu X. （Department of Ophthalmology, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai Key Laboratory of Fundus Disease, No. 100, Haining Rd, Shanghai, China Shanghai Key Laboratory of Fundus Disease, Shanghai, China）

出处： Cornea 2015 Vol.34 No.10 P1295-1302

关键词： angiogenesis;cornea;inhibitor;peptide;topical application

摘要： Purpose: To investigate the antiangiogenic effect of topical application of H-KI20, a novel 20-amino acid peptide from the hepatocyte growth factor, o ...

作者： Bai, M.;Shen, M.;Teng, Y.;Sun, Y.;Li, F.;Zhang, X.;Xu, Y.;Duan, Y.;Du, L. （a Department of Ultrasound, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China; b State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200032, China）

出处： Oncotarget 2015 Vol.6 No.41 P43779-43790

关键词： Combination therapy;Gene silencing;siRNA delivery;UTMD;Xenograft nude mice model

摘要： The overexpression of the breast cancer resistance protein (ABCG2) confers resistance to Adriamycin (ADR) in breast cancer. The silencing of ABCG2 usi ...

作者： Yu, G.;Li, S.;Wan, R.;Wang, X.;Hu, G. （a Department of Gastroenterology, Shanghai First People\'s Hospital, Shanghai Jiaotong University School of Medicine, 100 Haining Rd, Hongkou District, Shanghai, 200080, China; b Department of Cardiology, Shanghai Tenth People\'s Hospital, Tongji University School of Medicine, Shanghai, China）

出处： Pancreas 2015 Vol.44 No.4 P561-569

关键词： efficacy;meta-analysis;nafamostat mesilate;post-ERCP pancreatitis

摘要： Objectives We aimed to evaluate the efficacy of nafamostat on the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatiti ...

作者： Dou, X.;Xiao, J.;Jin, Z.;Zheng, P. （a Department of Gastroenterology, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, Jiangsu 210000, China; b Department of Gastroenterology, Shanghai East Hospital, Tongji University, Shanghai, 200085, China; c Department of Oncology, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai, 200085, China）

出处： Oncology Letters 2015 Vol.10 No.3 P1259-1266

关键词： 5-aminosalicylic acid;Colonic neoplasms;Peroxisome proliferator-activated receptor-γ;Ulcerative colitis

摘要： The aim of the present study was to evaluate the expression of peroxisome proliferator-activated receptor (PPAR)-γ in inflammatory bowel disease (IBD) ...

作者： Jia, R.;Tang, M.;Qiu, L.;Sun, R.;Cheng, L.;Ma, X.;Yin, G.;Hu, G.;Wang, X.;Zhao, Y. （a Department of Gastroenterology, Shanghai Tenth People\'s Hospital, Tongji University School of Medicine, Shanghai, China; b Department of Clinical Medicine, Soochow University School of Medicine, Suzhou, Jiangsu Province, China; c Department of Gastroenterology, Shanghai First People\'s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China）

出处： Pancreas 2015 Vol.44 No.2 P321-325

关键词： Acute pancreatitis;C-reactive protein;Interleukin-17;Interleukin-23

摘要： Objective: The interleukin (IL)-23/IL-17 axis plays an important role in various inflammatory conditions but its function in acute pancreatitis (AP) i ...

作者： Zheng, L.;Zheng, S.;Yuan, X.;Wang, X.;Zhang, Z.;Zhang, G. （a Department of radiology, Shanghai First People’s hospital, Shanghai Jiao Tong University, Shanghai, China; b Department of radiology, Feinberg school of Medicine, Northwestern University, Chicago, IL, United States; c Department of Obstetrics and gynecology, Dengfeng People’s hospital, Zhengzhou, China）

出处： OncoTargets and Therapy 2015 Vol.8 P1743-1751

关键词： Dynamic contrast-enhanced magnetic resonance imaging;Endometrial carcinoma;Preoperative staging;T2-weighted imaging

摘要： Purpose: This study aimed to compare dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with T2-weighted imaging (T2WI) for the preoperati ...

作者： Cui, J.;Quan, M.;Jiang, W.;Hu, H.;Jiao, F.;Li, N.;Jin, Z.;Wang, L.;Wang, Y.;Wang, L. （a Department of Oncology, Shanghai First People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China; b Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; c Shanghai Key Laboratory of Pancreatic Diseases, Shanghai, 200080, China）

出处： Medical Oncology 2015 Vol.32 No.5

关键词： Growth;LDHB;Metastasis;Pancreatic cancer

摘要： Lactate dehydrogenase B (LDHB) is widely expressed in adult somatic tissue and is one of the two subunits of lactate dehydrogenase, which is the key g ...

作者： Han, M.;Yu, D.;Song, Q.;Wang, J.;Dong, P.;He, J. （a Department of Otorhinolaryngology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China; b Shanghai Sixth People\'s Hospital, Shanghai Jiao Tong University, Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, 200233, China）

出处： Neuroscience Letters 2015 Vol.600 P164-170

关键词： Cochlear;Gene transduction;Lentivirus;Ototoxicity;Polybrene

摘要： Polybrene is widely used to enhance viral transduction; however, little is known about the utility thereof, in enhancing lentiviral transduction of co ...

作者： Li, Y.;Xu, G.;Huang, K.;Wang, J.;Zhang, J.;Liu, J.;Wang, Z.;Chen, G. （a Department of Urology, Jinshan Hospital, Fudan University, Shanghai, China; b Central Laboratory, Jinshan Hospital, Fudan University, Shanghai, China; c Department of Urology, Shanghai First People’s Hospital, Medical College of Shanghai Jiao Tong University, Shanghai, China）

出处： OncoTargets and Therapy 2015 Vol.8 P2121-2127

关键词： ASIC1;Biomarkers;Clear cell renal cell carcinoma

摘要： Background: Acidic extracellular pH is a major feature of tumor tissue. Acid-sensing ion channels (ASICs) represent an H + -gated subgroup of the dege ...

作者： Xiang Xia;Weidong Wu;Chen Huang;Gang Cen;Tao Jiang;Jun Cao;Kejian Huang;Zhengjun Qiu （1.Department of General Surgery,Shanghai Jiaotong University Affiliated First People’s Hospital,Shanghai,People’s Republic of China）

出处： Tumour Biology 2015 Vol.36 P111-119

摘要： Transforming growth factor-β (TGF-β) regulates cell functions and has key roles in pancreatic cancer development. SMAD4, as one of the Smads family of ...