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作者: Yu-Lei Zhang;Jun-Fang Zhang;Xi-Xi Wang;Yan Wang;Craig S. Anderson;Yun-Cheng Wu (Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People\'s Republic of China. \'(1)\' ; The George Institute, UNSW, Sydney, Australia. [2] ; Department of Neurology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People\'s Republic of China. yunchw@medmail.com.cn. [3])

出处: Journal of Neurology

关键词: Wake-up stroke;Magnetic resonance imaging;Computed tomography perfusion;Thrombolysis;Thrombectomy;PWI–DWI mismatch;DWI–FLAIR mismatch

摘要: Wake-up stroke (WUS) is a subgroup of ischemic stroke in which patients show no abnormality before sleep while wake up with neurological deficits. In ...

作者: Wei Wang;Jun Yao;Xiaohui Guo;Yushan Guo;Chaoli Yan;Kuanzhi Liu;Ying Zhang;Xiaoyue Wang;Hongmei Li;Zhongyuan Wen;Xinling Wang;Shuangqing Li;Xinhua Xiao;Weijuan Liu;Ziling Li;Lihui Zhang;Shiying Shao;Shandong Ye;Guijun Qin;Yiming Li;Feng Li;Xiaomei Zhang;Xuefeng Li;Yongde Peng;Hongyan Deng;Xiangjin Xu;Ligang Zhou;Yanli Huang;Mengya Cao;Xuefang Xia;Mingbiao Shi;Jing Dou;Jing Yuan (Peking University First Hospital, Beijing, China; Peking University First Hospital, Beijing, China; Peking University First Hospital, Beijing, China; Affiliated Hospital of Beihua University, Jilin, China; The Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia, China; The Third Hospital of Hebei Medical University, Hebei, China; The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China; The First People’s Hospital of Yueyang, Hunan, China; Emergency General Hospital, Beijing, China; Renmin Hospital of Wuhan University, Hubei, China; Xinjiang Uiger Municipal People’s Hospital, Xinjiang, China; West China Hospital, Sichuan University, Sichuan, China; Peking Union Medical College Hospital, Beijing, China; Chongqing Three Gorges Central Hospital, Chongqing, China; Inner Mongolia Baogang Hospital, Inner Mongolia, China; The second Hospital of Hebei Medical University, Hebei, China; Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China; Anhui Provincial Hospital, Anhui, China; The First Affiliated Hospital of Zhengzhou University, Henan, China; Huashan Hospital Affiliated to Fudan University, Shanghai, China; Jining First People’s Hospital, Shandong, China; The First Affiliated Hospital of Bengbu Medical College, Anhui, China; Shiyan Taihe Hospital, Hubei, China; Shanghai General Hospital, Shanghai, China; Wuhan Puai Hospital, Hubei, China; 900 Hospital of the Joint Logistics Support Force of Chinese PLA, Fujian, China; Shanghai Pudong Hospital, Shanghai, China; CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Hebei, China CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Hebei, China CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Hebei, China CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Hebei, China CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Hebei, China CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Hebei, China)

出处: Current Medical Research and Opinion

关键词: DBPR108;monotherapy;type 2 diabetes mellitus;DPP-4 inhibitor

摘要: Objective: DBPR108, a novel dipeptidyl-peptidase-4 inhibitor, has shown great antihyperglycemic effect in animal models. This study was to evaluate th ...

作者: Guogang Xie;Fengming Ding;Lei Han;Dongning Yin;Hongzhou Lu;Min Zhang (Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China;Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China;Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China;Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China;Department of Clinical Laboratory, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China;Min Zhang, Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, 100 Haining road, Hongkou District Shanghai, 200080 China.;Hongzhou Lu, Department of Clinical Laboratory, Shanghai Public Health Clinical Center, Fudan University, 2901 Caolang Road, Jinshan District, Shanghai, 201508 China.;Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China;Min Zhang, Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, 100 Haining road, Hongkou District Shanghai, 200080 China.;Hongzhou Lu, Department of Clinical Laboratory, Shanghai Public Health Clinical Center, Fudan University, 2901 Caolang Road, Jinshan District, Shanghai, 201508 China.)

出处: Allergy

关键词: COVID‐19;diagnosis;peripheral blood eosinophils;pneumonia;prognosis

摘要: Background Coronavirus disease 2019 (COVID‐19) emerged in Wuhan city and rapidly spread globally outside China. We aimed to investigate the role of p ...

作者: Huihao Chen, MD;Depeng Meng, MD;Zheng Xie, MD;Gang Yin, MD;Chunlin Hou, MD;Haodong Lin, MD, PhD (Department of Orthopedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People\'s Republic of China Department of Orthopedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People\'s Republic of China Department of Orthopedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People\'s Republic of China Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People\'s Republic of China Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People\'s Republic of China Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People\'s Republic of China)

出处: Operative Neurosurgery

关键词: Femoral nerve;Nerve injury;Nerve transfer;Reconstruction;Sciatic nerve

摘要: BACKGROUND Femoral nerve injury causes knee dysfunction, and high femoral nerve injury is difficult to repair. OBJECTIVE To evaluate the anatomic f ...

作者: Congying,Xia ;Marleen,Vonder ;Gert Jan,Pelgrim ;Mieneke,Rook ;Xueqian,Xie ;Abdullah,Alsurayhi ;Peter M A,van Ooijen ;Jurjen N,van Bolhuis ;Matthijs,Oudkerk ;Monique,Dorrius ;Pim,van der Harst ;Rozemarijn,Vliegenthart (University of Groningen, University Medical Center Groningen, Department of Radiology, Groningen, the Netherlands. Electronic address: c.xia@umcg.nl. \'(1)\' ; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands. Electronic address: m.vonder@umcg.nl. [2] ; University of Groningen, University Medical Center Groningen, Department of Radiology, Groningen, the Netherlands. Electronic address: g.j.pelgrim@umcg.nl. [3] ; University of Groningen, University Medical Center Groningen, Department of Radiology, Groningen, the Netherlands; Department of Radiology, Martini Hospital Groningen, Groningen, the Netherlands. Electronic address: m.rook@umcg.nl. [4] ; Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: xiexueqian@hotmail.com. [5] ; University of Groningen, Faculty of Medical Sciences, Groningen, the Netherlands. Electronic address: a.a.alsurayhi@student.rug.nl. [6] ; University of Groningen, University Medical Center Groningen, Department of Radiation Therapy, Groningen, the Netherlands. Electronic address: p.m.a.van.ooijen@umcg.nl. [7] ; Lifelines Cohort Study, Groningen, the Netherlands. Electronic address: j.n.van.bolhuis@lifelines.nl. [8] ; University of Groningen, Faculty of Medical Sciences, Groningen, the Netherlands; Institute for Diagnostic Accuracy, Groningen, the Netherlands. Electronic address: m.oudkerk@rug.nl. [9] ; University of Groningen, University Medical Center Groningen, Department of Radiology, Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands. Electronic address: m.d.dorrius@umcg.nl. [10] ; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands. Electronic address: p.van.der.harst@umcg.nl. [11] ; University of Groningen, University Medical Center Groningen, Department of Radiology, Groningen, the Netherlands. Electronic address: r.vliegenthart@umcg.nl. [12])

出处: Journal of cardiovascular computed tomography

关键词: Computed tomography;Coronary artery calcium score;Dual source;High pitch

摘要: To determine the effect of low-dose, high-pitch non-electrocardiographic (ECG)-triggered chest CT on coronary artery calcium (CAC) detection, quantifi ...

作者: Xia Wu;Heng Wu;Wenjiang Sun;Chen Wang (Department of Endocrinology, Jing\'an District Centre Hospital of Shanghai (Huashan Hospital Fudan University Jing\'an Branch), Shanghai, China. \'(1)\' ; Department of Psychosomatic Medicine, Shanghai Tongji Hospital, School of Medicine, Tongji University, Shanghai, China. [2] ; Department of Rehabilitation, Shanghai General Hospital, Jiaotong University, Shanghai, China. [3] ; Department of General Medicine, Shanghai Tongji Hospital, School of Medicine, Tongji University, Shanghai, China. wangchen09443@163.com. [4])

出处: Hormones

关键词: Polycystic ovary syndrome;Anti-Müllerian hormone;Aerobic exercise;Oxidative stress

摘要: Purpose Structured exercise is shown to be one of the most effective lifestyle interventions for women with polycystic ovary syndrome (PCOS). Anti-Mü ...

作者: Mengqing,Zhang ;Chao,Li ;Fang,Zhang ;Xiaoxiao,Han ;Qinglu,Yang ;Tuo,Lin ;Huichang,Zhou ;Min,Tang ;Jungui,Zhou ;Hongling,Shi ;Yanping,Hui ;Mingfeng,Xiong ;Ling,Pang ;Baolan,Wang ;Zhen,Feng ;Zhanfei,Li ;Changbing,Cao ;Xiao,Lu ;Yuanyuan,Ding ;Shukun,Shen ;Zhengyue,Xu ;Fan,Yu ;Chen,Chen ;Ling,Meng ;Guiqing,Liao ;Jinxin,Zhang ;Ayodele,Sasegbon ;Zulin,Dou (Department of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, No. 600, Tianhe Road, Guangzhou, 510630, Guangdong, China. \'(1)\' ; Department of Rehabilitation Medicine, Guangzhou First People\'s Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China. [2] ; Department of Rehabilitation Medicine, The First People\'s Hospital of Foshan, Foshan, Guangdong, China. [3] ; Department of Neurological Rehabilitation Medicine, Ningbo Rehabilitation Hospital, Ningbo, Zhejiang, China. [4] ; Department of Rehabilitation Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangzhou, Guangdong, China. [5] ; Department of Rehabilitation Medicine, Third People\'s Hospital of Yunnan Province, Kunming, Yunnan, China. [6] ; Department of Rehabilitation Medicine, The Second Affiliated Hospital, Xi\'an Jiaotong University School of Medicine, Xi\'an, Shanxi, China. [7] ; Department of Rehabilitation Medicine, First Affiliated Hospital of Army Medical University, Chongqing, China. [8] ; Department of Rehabilitation Medicine, China-Japan Union Hospital of Jilin University, Jilin, Changchun, China. [9] ; Department of Rehabilitation Medicine, The First Affiliated Hospital of Xinjiang University and Xinjiang Medical University, Urumqi, Xinjiang, China. [10] ; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. [11] ; Department of Rehabilitation Medicine, Affiliated Hospital of Qingdao University, Qingdao, Shandong, China. [12] ; Department of Rehabilitation Medicine, Fujian Longyan Longgang Hospital, Longyan, Fujian, China. [13] ; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. [14] ; Department of Rehabilitation Medicine, Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [15] ; Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [16] ; Department of Rehabilitation Medicine, Qinghai Provincial People\'s Hospital, Xining, Qinghai, China. [17] ; Department of Rehabilitation Medicine, Shanghai General Hospital, Shanghai, China. [18] ; Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China. [19] ; Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. [20] ; Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China. [21] ; Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China. [22] ; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, Centre for Gastrointestinal Sciences, School of Medical Sciences, The University of Manchester, Clinical Sciences Building, Salford Royal NHS Foundation Trust, Manchester, UK. [23] ; Department of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, No. 600, Tianhe Road, Guangzhou, 510630, Guangdong, China. douzul@163.com. [24])

出处: Dysphagia

关键词: Chinese elderly;Comorbidity;Deglutition;Deglutition disorders;Dysphagia;Epidemiology

摘要: To determine the prevalence of dysphagia among an older population and patients with stroke, head and neck cancers (HNCs) or neurodegenerative disease ...

作者: Beibei,Jiang ;Ning,Guo ;Yinghui,Ge ;Lu,Zhang ;Matthijs,Oudkerk ;Xueqian,Xie (Radiology Department \'(1)\' ; Shanghai General Hospital [2] ; Shanghai Jiao Tong University School of Medicine [3] ; Haining Rd.100 [4] ; Shanghai 200080 [5] ; China. [6] ; Shukun (Beijing) Technology Co [7] ; Ltd. [8] ; Jinhui Bd [9] ; Qiyang Rd [10] ; Beijing 100102 [11] ; Central China Fuwai Hospital [12] ; Fuwai Avenue 1 [13] ; Zhengzhou 450046 [14] ; Institute for DiagNostic Accuracy [15] ; Prof. Wiersma Straat 5 [16] ; 9713GH Groningen [17] ; The Netherlands. [18] ; University of Groningen [19] ; Faculty of Medical Sciences [20] ; 9700AB Groningen [21])

出处: The British journal of radiology P20190812

摘要: In this review, we describe the technical aspects of artificial intelligence (AI) in cardiac imaging, starting with radiomics, basic algorithms of dee ...

作者: Zhongquan Zhou;Songwen Chen;Zhiming Tian;Shibing Deng;Xuying Yi;Shaning Yang;Xuexin Yang;Lijun Jin;Wanqing Shi (Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, Shanghai General Hospital, Shanghai 200000, China Department of Cardiology, First School of Clinical Medicine College, Yangtze University, Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China The First Hospital of Jingzhou City, The Interventional Center, Jingzhou 434000, China)

出处: Acta Biochimica et Biophysica Sinica

关键词: hypoxia-inducible factor-1;cardiomyocytes;hypoxia;miR-20b-5p;NF-κB

摘要: Chronic hypoxia is a common inducer of end-stage cardiovascular disease. In cells under hypoxia, the hypoxia-inducible factor-1 (HIF-1) plays a vital ...

作者: Jianhua Ma;Bin Zhang;Jianing Hou;Yongde Peng (Department of Endocrinology, Nanjing First Hospital, Nanjing, China Lilly China Drug Development and Medical Affairs Center, Shanghai, China Department of Endocrinology and Metabolism, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China)

出处: Diabetes Therapy

关键词: Dulaglutide;East Asian patients;Type 2 diabetes

摘要: Introduction This subgroup analysis assessed the efficacy and safety of once weekly dulaglutide 1.5 mg and 0.75 mg in East Asian patients with type 2 ...

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