作者： Zhou, Yangyang;Wang, Liwei （Department of Medical Oncology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 201620, China）

出处： Tumor 2015 Vol.35 No.7 P810

摘要： Exosomes are small vesicular bodies of 40-100 nm secreted by various types of living cells into the extracellular environment, and contain proteins, l ...

作者： Hang, Donghua;Li, Xia;Cao, Lei;Zhu, Zonghao;Wang, Jiandong;Xu, Qiaolong;Wang, Qiugen;Li, Fan （Department of Orthopaedics, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China）

出处： Fudan University Journal of Medical Sciences 2015 Vol.42 No.3 P307

摘要： Objective: To determining whether receptor-interacting protein kinase 1 (RIPK1) could inhibit glucocorticoid (GC) induced-apoptosis of mesenchymal ste ...

作者： Zhong, SS (Zhong, Shuangshuang)^1,2,3;Yin, HJ (Yin, Huijing)^1,2,3;Liao, YL (Liao, Yueling)^1,2,3;Yao, F (Yao, Feng)⁴;Li, Q (Li, Qi)⁵;Zhang, J (Zhang, Jie)⁶;Jiao, HK (Jiao, Huike)⁷;Zhao, YX (Zhao, Yongxu)⁷;Xu, DL (Xu, Dongliang)^1,2;Liu, SL (Liu, Shuli)^1,8 （Key Laboratory of Cell Differentiation and Apoptosis, Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China Department of Oncology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Translation Medicine Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China Insitute of Health Science, Shanghai Institute of Biological Science, Chinese Academy of Science, Shanghai, China Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People\'s Hospital, College of Stomatology, Shanghai Jiao Tong University, School of Medicine, Shanghai, China Department of Oncology, Shanghai East Hospital, Tongji University, Shanghai, China Department of Molecular and Cellular Biochemistry, Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, United States）

出处： Cancer Research 2015 Vol.75 No.9 P1801-1814

关键词： GROWTH-FACTOR RECEPTOR;OBSTRUCTIVE PULMONARY-DISEASE;PROTEIN-COUPLED RECEPTOR;NF-KAPPA-B;CANCER GENOME;GENE;INFLAMMATION;ACTIVATION;FAMILY;MICE

摘要： GPRC5A is a G-protein–coupled receptor expressed in lung tissue but repressed in most human lung cancers. Studies in Gprc5a−/− mice have established i ...

作者： Zhang, ZX (Zhang, Zhengxiang)^1,2;Wang, M (Wang, Min)³;Zhou, L (Zhou, Ling)³;Feng, X (Feng, Xiao)^1,2;Cheng, J (Cheng, Jin)^1,2;Yu, Y (Yu, Yang)^1,2;Gong, YP (Gong, Yanping)⁴;Zhu, Y (Zhu, Ying)³;Li, CY (Li, Chuanyuan)⁵;Tian, L (Tian, Ling)⁴ （The Comprehensive Cancer Center & Shanghai Key Laboratory for Pancreatic Diseases, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. kanardo@163.com.;The Department of Surgery, The Branch Hospital of Shanghai General Hospital, Shanghai, 200080, China. minniewang01@163.com.;The Department of Surgery, The Branch Hospital of Shanghai General Hospital, Shanghai, 200080, China. zhouling_2005@126.com.;The Comprehensive Cancer Center & Shanghai Key Laboratory for Pancreatic Diseases, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. fxngtg@163.com.;The Comprehensive Cancer Center & Shanghai Key Laboratory for Pancreatic Diseases, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. ajinch@163.com.;The Comprehensive Cancer Center & Shanghai Key Laboratory for Pancreatic Diseases, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. yuyang1611@163.com.;Experimental Research Center, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. yanpinggong2003@aliyun.com.;The Department of Surgery, The Branch Hospital of Shanghai General Hospital, Shanghai, 200080, China. rabbityy1975@163.com.;Department of Dermatology, Medical Center, Duke University, Durham, NC, 27710, USA. chuan.li@duke.edu.;Experimental Research Center, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. tl09168@hotmail.com.;The Comprehensive Cancer Center & Shanghai Key Laboratory for Pancreatic Diseases, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, China. qianh2011@126.com.;）

出处： J Exp Clin Cancer Res 2015 Vol.34 No.1 P51

关键词： GLYCATION END-PRODUCTS;RAGE;RECEPTOR;ADENOCARCINOMA;RADIOTHERAPY;REPOPULATION;ACTIVATION;EXPRESSION;NECROSIS;PROTEIN

摘要： BACKGROUND: Dying tumor cells after irradiation could promote the proliferation of living tumor cells might cause tumor relapse and treatment failure. ...

作者： Zhang, Baowei;Gong, Hui;Zhang, Jie （Department of Physical Education, Shanghai Lixin University of Commerce, Shanghai, 200235, China; Departemnt of Radiology, Shanghai General Hospital, Shanghai, 200013, China; Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China）

出处： Fudan University Journal of Medical Sciences 2015 Vol.42 No.6 P733

摘要： Objective: To explore whether the occurrence of coronary heart disease prevented by sport has relationship to the low level of plasma oxidized low den ...

作者： Wang, PS (Wang, Pusen)¹;Wang, CG (Wang, Chunguang)¹;Li, H (Li, Hao)¹;Shi, BJ (Shi, Baojie)¹;Wang, JN (Wang, Jianning)²;Zhong, L (Zhong, Lin)¹ （Affiliations 1 Department of General Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai. 2 Department of Urology, Affiliated Qianfoshan Hospital, Shandong University, Jinan, People\'s Republic of China.）

出处： OncoTargets and Therapy 2015 Vol.2015 No.1 P3775-3781

关键词： age;hepatocellular carcinoma;liver transplantation;prognosis

摘要： Background: Liver transplantation (LT) offers the most effective treatment for hepatocellular carcinoma patients. Various preoperative variables are c ...

作者： Sun, ZY (Sun, Zhongyi)¹;Yin, ZM (Yin, Zhanmin)²;Liu, C (Liu, Chao)¹;Liang, H (Liang, He)¹;Jiang, MB (Jiang, Minbo)¹;Tian, JW (Tian, Jiwei)¹ （a Shanghai General Hospital Affiliated to Shanghai Jiao Tong University, Department of Orthopedics, School of Medicine, 100, Haining Road, Shanghai, 200080, China; b Central Hospital of Tai An, Spine and Joint Surgery, Shandong, China）

出处： Journal of Orthopaedic Surgery and Research 2015 Vol.10 No.1 P159

关键词： ADAMTS enzymes;Aggrecan;Human intervertebral disc;IL-1β;NF-κB

摘要： The purpose of this study is to investigate IL-1β regulation of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS-4 and ADAMTS-5) ...

作者： Wang, Lily C.;Al Awamlh, Bashir Al Hussein;Hu, Jim C.;Laudano, Melissa A.;Davison, Wesley L.;Schulster, Michael L.;Zhao, Fujun;Chughtai, Bilal;Lee, Richard K. （Affiliations 1 Department of Urology, Weill Medical College of Cornell University, New York, NY. 2 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. 3 Department of Urology, Weill Medical College of Cornell University, New York, NY. Electronic address: ril9010@med.cornell.edu.）

出处： UROLOGY 2015 Vol.86 No.5 P885-891

关键词： UNITED-STATES;SURGERY;SACROCOLPOPEXY

摘要： OBJECTIVE To investigate recent trends in mesh use for pelvic organ prolapse (POP)-related reconstruction procedures. MATERIALS AND METHODS Using the ...

作者： Zhang, Y (Zhang, Yu)¹;Tang, Y (Tang, Yin)¹;Sun, S (Sun, Shuai)¹;Wang, ZH (Wang, Zhihua)¹;Wu, WJ (Wu, Wenjun)¹;Zhao, XD (Zhao, Xiaodong)³;Czajkowsky, DM (Czajkowsky, Daniel M.)³;Li, Y (Li, Yan)⁵;Tian, JH (Tian, Jianhui)⁶;Xu, L (Xu, Ling)⁶ （Key Laboratory of Systems Biomedicine (Ministry of Education), State Key Laboratory of Oncogenes and Related Genes, School of Biomedical Engineering, and Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200240, P.R. China Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai 200071, P.R. China Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, P.R. China Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, United States）

出处： ANALYTICAL CHEMISTRY 2015 Vol.87 No.19 P9761-9768

关键词： BREAST-CANCER PATIENTS;LUNG-CANCER;NETWORKS;CHIP;EGFR;HETEROGENEITY;METASTASIS;RESISTANCE;PLATFORM;THERAPY

摘要： The high glucose uptake and activation of oncogenic signaling pathways in cancer cells has long made these features, together with the mutational spec ...

作者： Li, Z (Li, Zhao)¹;Ye, B (Ye, Bo)²;Bao, MW (Bao, Minwei)³;Xu, BB (Xu, Binbin)¹;Chen, QY (Chen, Qinyi)⁴;Liu, SD (Liu, Sida)¹;Han, YD (Han, Yudong)¹;Peng, MZ (Peng, Mingzhen)¹;Lin, ZF (Lin, Zhifeng)¹;Li, JP (Li, Jingpei)⁵ （1 Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of medicine, Shanghai, China 2 Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China 3 Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Shanghai Tongji University School of Medicine, Shanghai, China 4 Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China 5 Department of Thoracic Surgery, Guangzhou Medical University First Affiliated Hospital, Guangdong Province, China）

出处： PLoS ONE 2015 Vol.10 No.9 P1-12

关键词： Research Article

摘要： Objective: This study was to define preoperative predictors from radiologic findings for the pathologic risk groups based on long-term surgical outcom ...