作者： Zhongquan Zhou;Songwen Chen;Zhiming Tian;Shibing Deng;Xuying Yi;Shaning Yang;Xuexin Yang;Lijun Jin;Wanqing Shi （Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, Shanghai General Hospital, Shanghai 200000, China Department of Cardiology, First School of Clinical Medicine College, Yangtze University, Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China The First Hospital of Jingzhou City, The Interventional Center, Jingzhou 434000, China）

出处： Acta Biochimica et Biophysica Sinica

关键词： hypoxia-inducible factor-1;cardiomyocytes;hypoxia;miR-20b-5p;NF-κB

摘要： Chronic hypoxia is a common inducer of end-stage cardiovascular disease. In cells under hypoxia, the hypoxia-inducible factor-1 (HIF-1) plays a vital ...

作者： Jianhua Ma;Bin Zhang;Jianing Hou;Yongde Peng （Department of Endocrinology, Nanjing First Hospital, Nanjing, China Lilly China Drug Development and Medical Affairs Center, Shanghai, China Department of Endocrinology and Metabolism, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China）

出处： Diabetes Therapy

关键词： Dulaglutide;East Asian patients;Type 2 diabetes

摘要： Introduction This subgroup analysis assessed the efficacy and safety of once weekly dulaglutide 1.5 mg and 0.75 mg in East Asian patients with type 2 ...

作者： Yumeng Cao;Xia Chen;Yuqi Liu;Xingyi Zhang;Yun Zou;Jinbao Li （Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Inflammation Research

关键词： PIM1;Acute lung injury;Pulmonary microvascular endothelial cells;ELK3;ICAM1

摘要： Objective The dysfunction of pulmonary microvascular endothelial cells (PMVECs) is one of the critical characteristics of acute lung injury/acute res ...

作者： Dao-Nan Chen;Jiang Du;Yun Xie;Ming Li;Rui-Lan Wang;Rui Tian （Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China）

出处： International Urology and Nephrology

关键词： AKI;Potassium;Sodium

摘要： Purpose Acute kidney injury (AKI) is a common organ dysfunction in ICU and up to now there is no good way to predict the AKI progression and patient ...

作者： Liu B.;Xie Y.;Wu Z. （a Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China b Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China）

出处： Dermatology P1-9

关键词： Nonsegmental vitiligo;Microarray data;Integrated analysis

摘要： Background: Nonsegmental vitiligo (NSV) is an acquired depigmentation disorder of unknown origin. Enormous interests focus on finding novel biomarkers ...

作者： Zhuang Yu;Tingting Wang;Liming Zhang;Xiaohu Yang;Quan Li;Xibing Ding （Department of Anesthesiology, Shanghai General Hospital, Jiaotong University School of Medicine, Shanghai, China Department of Anesthesiology, Huashan Hospital, Fudan University School of Medicine, Shanghai, China Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, USA Department of Anesthesiology, Shanghai East Hospital, Shanghai, China Department of Anesthesiology, Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen, China Department of Anesthesiology, Shanghai Renji Hospital, Jiaotong University School of Medicine, Shanghai, China）

出处： Inflammation

作者： Jiamin Xie;Qiuying Chen;Guangyi Hu;Yao Yin;Haidong Zou;Jiangnan He;Jianfeng Zhu;Ying Fan;Xun Xu （Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Shanghai Key Laboratory of Ocular Fundus Disease, Shanghai Jiao Tong University School of Medicine, Shanghai, China Shanghai Engineering Center for Visual Science and Photo Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Graefe\'s Archive for Clinical and Experimental Ophthalmology

关键词： CNV-related macular atrophy;Dome-shaped macula;Patchy atrophy;Scleral thickness;Scleral perforating vessels;Swept-source optical coherence tomography

摘要： Purpose To investigate morphological differences between two types of Bruch’s membrane (BM) defects—patchy atrophy (PA) and CNV-related macular atrop ...

作者： Shuyu,Xiong ;Xiangui,He ;Bo,Zhang ;Junjie,Deng ;Jingjing,Wang ;Minzhi,Lv ;Jianfeng,Zhu ;Haidong,Zou ;Xun,Xu （Department of Preventative Ophthalmology \'(1)\' ; Shanghai Eye Disease Prevention and Treatment Center [2] ; Shanghai Eye Hospital [3] ; Shanghai [4] ; China; Department of Ophthalmology [5] ; Shanghai Key Laboratory of Ocular Fundus Disease [6] ; Shanghai General Hospital [7] ; Shanghai Engineering Center for Visual Science and Photomedicine [8] ; Shanghai Jiao Tong University [9] ; China. [10] ; China. Electronic address: xianhezi@163.com. [11]）

出处： American journal of ophthalmology

摘要： To clarify the changing characteristics of choroidal thickness over time within different age ranges and among different refractive statuses of childr ...

作者： Xieyi Yao¹;Chong Chen¹;Jian Zhang¹;Yupeng Xu¹;Shuyu Xiong¹;Qing Gu¹;Xun Xu¹CA1;Yan Suo² （1 a Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;b National Clinical Research Center for Eye Diseases, Shanghai, China;c Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China;d Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China;e Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China; 2 a Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;b National Clinical Research Center for Eye Diseases, Shanghai, China;c Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China;f Shanghai Eye Diseases Prevention and Treatment Center/Shanghai Eye Hospital, Shanghai, China）

出处： Current Eye Research

关键词： Peptide;neurotrypsin;kringle;NT/K-CFY;neovascularization

摘要： Purpose : To assess the anti-neovascularization effect of a novel peptide NT/K-CFY derived from the kringle domain of neurotrypsin. Materials and M ...

作者： Cai-Guo Yu;Fang-Fei Wei;Zhen-Yu Zhang;Lutgarde Thijs;Wen-Yi Yang;Blerim Mujaj;Ying-Mei Feng;José Boggia;Harry A. Roels;Harry A. J. Struijker-Boudier;Tim S. Nawrot;Peter Verhamme;Jan A. Staessen （Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; ; Department of Endocrinology, Beijing Luhe Hospital and, Key Laboratory of Diabetes Prevention and Research, Capital Medical University, Beijing, China; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; ; Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Department of Endocrinology, Beijing Luhe Hospital and, Key Laboratory of Diabetes Prevention and Research, Capital Medical University, Beijing, China; Unidad de Hipertensión Arterial, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium; Department of Pharmacology, Maastricht University, Maastricht, The Netherlands; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium; Centre for Molecular and Vascular Biology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; ; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands）

出处： Blood Pressure

关键词： arterial stiffness;central blood pressure;central hemodynamics;lead;environmental medicine

摘要： Purpose: Arterial stiffness predicts cardiovascular complications. The association between arterial stiffness and blood lead (BL) remains poorly docum ...