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作者: Duong, Hien T. T.;Dong, Zhixia;Su, Lin;Boyer, Cyrille;George, Jacob;Davis, Thomas P.;Wang, Jianhua

出处: Small 2015

摘要: Polymeric nanoparticles are designed to transport and deliver nitric oxide (NO) into hepatic stellate cells (HSCs) for the potential treatment of both ...

作者: Chen, Y.;Qiao, J.

出处: ALLERGOLOGIA ET IMMUNOPATHOLOGIA 2015 Vol.43 No.6 P584-592

摘要: Background: Asthma is a chronic inflammatory airway disease, the incidence of which has increased recently. In order to identify the potential biomark ...

作者: Zhang, Qing;Zhao, Wei;Ye, Changxiao;Zhuang, Junlong;Chang, Cunjie;Li, Yuying;Huang, Xiaojing;Shen, Lan;Li, Yan;Cui, Yangyan;Song, Jiannan;Shen, Bing;Eliaz, Isaac;Huang, Ruimin;Ying, Hao;Guo, Hongqian;Yan, Ju

出处: ONCOTARGET 2015 Vol.6 No.35 P37335-37348

摘要: The oncoprotein EZH2, as a histone H3K27 methyltransferase, is frequently overexpressed in various cancer types. However, the mechanisms underlying it ...

作者: Jiang, P (Jiang, P.);Li, H (Li, H.);Li, X (Li, X.) (;[ 1 ] Shandong Univ Tradit Chinese Med, Jinan 250011, Peoples R China [ 2 ] Shanghai Jiao Tong Univ, Dept Surg, Affiliated Peoples Hosp 1, Shanghai 200030, Peoples R China [ 3 ] Shandong Univ Tradit Chinese Med, Affiliated Hosp, Jinan 250011, Peoples R China)

出处: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 2015 Vol.33 No.1 P115-121

关键词: rheumatoid arthritis;diabetes mellitus;risk factor;meta-analysis

摘要: Objective. The aim of this study was to investigate the relationship between rheumatoid arthritis (RA) and the occurrence of diabetes mellitus (DM). M ...

作者: Zhou, Xiaolin( zhou_xiaolin@163.com);Xu, Jie( jiexu@yahoo.com) (1 Department of Neurology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China 2 Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Jiao Tong University, Shanghai, China 3 Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China)

出处: Neurobiol Aging. 2015 Vol.36 No.11 P2925-2931

关键词: Alzheimer's disease;Long noncoding RNA;Microarray

摘要: Alzheimer's disease (AD) is the most common dementia among the elderly that involves complex neurodegenerative alterations. Multiple cellular processe ...

作者: Li J, Qin S, Xu R, Yau TC, Ma B, Pan H, Xu J, Bai Y, Chi Y, Wang L, Yeh KH, Bi F, Cheng Y, Le AT, Lin JK, Liu T, Ma D, Kappeler C, Kalmus J, Kim TW;CONCUR Investigators. (1 Department of Medical Oncology, Fudan University Shanghai Cancer Center, and Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. 2 Department of Medical Oncology, Chinese People's Liberation Army Cancer Center of Nanjing Bayi Hospital, Nanjing, China. 3 Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China. 4 Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China. 5 Department of Clinical Oncology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China. 6 Medical Oncology, Sir Run Run Shaw Hospital Medical School, Zhejiang University, Hangzhou, China. 7 Beijing 307 People's Liberation Army Hospital Cancer Centre, Beijing, China. 8 Third Affiliated Hospital of Harbin Medical University, Harbin, China. 9 Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China. 10 Comprehensive Cancer Center, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai, China. 11 Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan. 12 Department of Medical Oncology, West China Hospital, Sichuan University, Chengdu, China. 13 Jilin Provincial Tumor Hospital, Changchun, China. 14 Department of Oncology, Cho Ray Hospital, Ho Chi Minh City, Vietnam. 15 Department of Surgery, Taipei Veterans General Hospital, National Yang-Ming University, Taipei, Taiwan. 16 Department of Medical Oncology, Zhong Shan Hospital, Fudan University, Shanghai, China. 17 Department of Medical Oncology, Guangdong General Hospital, Guangzhou, Guangdong, China. 18 Bayer Pharma AG, Berlin, Germany. 19 Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, South Korea. Electronic address: twkimmd@amc.seoul.kr.)

出处: Lancet Oncol. 2015 Vol.16 No.6 P619-629

摘要: BACKGROUND: In the international randomised phase 3 CORRECT trial (NCT01103323), regorafenib significantly improved overall survival versus placebo in ...

作者: Ma, J (Ma, Jing)1,2;Xing, LX (Xing, Lingxi)1;Shen, M (Shen, Ming)3;Li, F (Li, Fan)1;Zhu, MJ (Zhu, Mingjie)3;Jin, LF (Jin, Lifang)1;Li, ZJ (Li, Zhaojun)1;Gao, FF (Gao, Ffeng)1;Su, YJ (Su, Yijin)1;Duan, YR (Duan, Yourong)3 (;[ 1 ] Shanghai Jiao Tong Univ, Sch Med, Shanghai Gen Hosp, Dept Ultrasound, Shanghai 200030, Peoples R China [ 2 ] Tongji Univ, Shanghai East Hosp, Dept Cardiovasc Ultrasound, Shanghai 200092, Peoples R China [ 3 ] Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Inst Canc, Shanghai 200030, Peoples R China)

出处: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 2015 Vol.36 PS60

作者: Qingzhong Liu;Huanqiang Zhao;Lizhong Han;Wen Shu;Qiong Wu;Yuxing Ni (c Department of Clinical Laboratory, Shanghai Sixth People\'s Hospital, Shanghai Jiaotong University, Shanghai, China a Department of Clinical Laboratory, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai, China b Department of Clinical Microbiology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China)

出处: Diagnostic Microbiology and Infectious Disease 2015 Vol.82 No.4 P278-283

关键词: MuH MRSA;Biocide resistance genes;Chlorhexidine;Decreased susceptibility

摘要: The aim of this study was to determine the prevalence of biocide-resistant determinants and the susceptibility to chlorhexidine in high-level mupiroci ...

作者: Ji, Xiaoxi;Chen, Qingshan;Thoreson, Andrew R.;Qu, Jin;An, Kai-Nan;Amadio, Peter C.;Steinmann, Scott P.;Zhao, Chunfeng (Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic, Rochester, MN 55905, USA Trauma Center, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai 200080, China Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA)

出处: Clinical Biomechanics 2015 Vol.30 No.9 P976-980

摘要: Background To compare the mechanical performance of a rotator cuff repaired with a novel tendon–fibrocartilage–bone composite bridging patch vs the tr ...

作者: Zongguang Tai;Xiaoyu Wang;Jing Tian;Yuan Gao;Lijuan Zhang;Chong Yao;Xin Wu;Wei Zhang;Quangang Zhu;Shen Gao (Department of Pharmaceutics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China § Department of Pharmaceutics, Shanghai First People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China ∥ Department of Pharmacy, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China)

出处: Biomacromolecules 2015 Vol.16 No.4 P1119-1130

摘要: RNA-based delivery system for cancer therapy remains a challenge. In this study, a stearyl-peptide (SHR) was synthesized using arginine, histidine, cy ...

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