作者： Zeyin,Rong ;Zai,Luo ;Jianming,Zhang ;Tengfei,Li ;Zhonglin,Zhu ;Zhilong,Yu ;Zhongmao,Fu ;Zhengjun,Qiu ;Chen,Huang （Department of General Surgery \'(1)\' ; Shanghai General Hospital [2] ; Shanghai Jiaotong University School of Medicine [3] ; Shanghai [4] ; China. [5]）

出处： Cancer science

关键词： GINS4;KLF4;biomarker;colorectal cancer;growth

摘要： GINS complex subunit 4 (GINS4) is essential for DNA replication initiation and elongation in the G 1 /S phase cell cycle in eukaryotes, however, its ...

作者： Yi,Zheng ;Shujun,Xia ;Xinping,Ren ;Weiwei,Zhan ;Zhan,Zheng ;Zhijie,Chen （Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, China. \'(1)\' ; Department of Ultrasound, Shanghai First People\'s Hospital, Shanghai JiaoTong University, Shanghai, China. [2] ; School of Systems Engineering, National University of Defense Technology, Changsha, Hunan, China. [3] ; Shenzhen Mindary Biomedical Electronics Co., Ltd. Shenzhen, Guangdong Sheng, China. [4]）

出处： Clinical hemorheology and microcirculation

关键词： Spleen elastography;chronic hepatitis B;liver fibrosis;shear-wave elastography;transient elastography

摘要： To evaluate the value of spleen shear-wave elastography (sound touch elastography [STE], sound touch quantification [STQ]) in indirect prediction of l ...

作者： Chao Gu;Zhenbo Zhang;Yinhua Yu;Yingtao Liu （Chao Gu ( Obstetrics and Gynecology Hospital, Fudan University, Shanghai) ; Zhenbo Zhang ( Department of Obstetrics and Gynecology, Shanghai First People’s Hospital, Jiao Tong University, Shanghai) ; Yinhua Yu ( Obstetrics and Gynecology Hospital, Fudan University, Shanghai) ; Yingtao Liu ( Obstetrics and Gynecology Hospital, Fudan University, Shanghai)）

出处： Cancer Science Vol.102 No.3 P557-564

摘要： Progestin resistance is the main obstacle to successful conservative therapy in young endometrial cancer patients. To investigate the molecular events ...

作者： Dongli,Li ;Yuanyuan,Gong （Shanghai engineering center for precise diagnosis and treatment of eye diseases，Shanghai. China. \'(1)\' ; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai. China. [2]）

出处： Current stem cell research & therapy

关键词： Exosome;Anterior ischemic optic neuropathy;Mesenchymal stem cellExosome;Anterior ischemic optic neuropathy;Mesenchymal stem cell

摘要： Non-arteritic anterior ischemic optic neuropathy (NAION) is a leading cause of optic nerve-related permanent visual impairment among individuals of ov ...

作者： Karoline K. Barkjohn;Christina Norris;Xiaoxing Cui;Lin Fang;Tongshu Zheng;James J. Schauer;Zhen Li;Yinping Zhang;Marilyn Black;Junfeng (Jim) Zhang;Michael H. Bergin （;Civil and Environmental Engineering, Duke University, Durham, NC, USA;Karoline K. Barkjohn, Civil and Environmental Engineering, Duke University, 121 Hudson Hall, Box 90287, Durham, NC 27708 USA.;Contribution: Conceptualization (lead), Data curation (equal), Formal analysis (lead), ​Investigation (equal), Methodology (lead), Writing - original draft (lead);Civil and Environmental Engineering, Duke University, Durham, NC, USA;Contribution: Conceptualization (supporting), Data curation (equal), ​Investigation (equal), Methodology (supporting), Writing - review &editing (supporting);Nicholas School of the Environment, Duke University, Durham, NC, USA;Contribution: Conceptualization (supporting), ​Investigation (supporting), Writing - review &editing (supporting);School of Architecture, Tsinghua University, Beijing, China;Contribution: ​Investigation (equal), Writing - review &editing (supporting);Civil and Environmental Engineering, Duke University, Durham, NC, USA;Contribution: Data curation (supporting), Formal analysis (supporting);Civil and Environmental Engineering, University of Wisconsin at Madison, Madison, WI, USA;Contribution: Conceptualization (supporting), Funding acquisition (equal), Writing - review &editing (supporting);Shanghai First People’s Hospital, Shanghai Shi, China;Contribution: ​Investigation (supporting), Resources (supporting);School of Architecture, Tsinghua University, Beijing, China;Contribution: Resources (supporting), Writing - review &editing (supporting);Underwriters Laboratories Inc., Marietta, GA, USA;Contribution: Conceptualization (supporting), Funding acquisition (equal);Nicholas School of the Environment, Duke University, Durham, NC, USA;Contribution: Conceptualization (supporting), Funding acquisition (equal), Writing - review &editing (supporting);Civil and Environmental Engineering, Duke University, Durham, NC, USA;Contribution: Conceptualization (supporting), Funding acquisition (lead), Supervision (lead), Writing - review &editing (lead)）

出处： Indoor Air

关键词： air filtration;air sensors;ozone;personal exposure;PM_2.5;portable air cleaner

摘要： Portable air cleaners are increasingly used in polluted areas in an attempt to reduce human exposure; however, there has been limited work characteriz ...

作者： Fei,Xie ;Zhengqun,Liu ;Ming,Liu ;Liang,Chen ;Wei,Ding ;Hongfu,Zhang （State Key Laboratory of Animal Nutrition \'(1)\' ; Institute of Animal Science [2] ; Chinese Academy of Agricultural Sciences [3] ; Beijing 100193. China. [4] ; Department of Gerontology [5] ; Shanghai General Hospital [6] ; Shanghai Jiao Tong University [7] ; Shanghai. China. [8]）

出处： Current protein & peptide science

关键词： Glycolipid metabolism;amino acids (AAs);intestinal microbial composition;short chain fatty acids (SCFAs)

摘要： Amino acids (AAs) and their metabolites regulate key metabolic pathways that are necessary for growth, reproduction, and immunity, metabolism of the b ...

作者： Kun,Wang ;Jiaxing,Sun ;Wei,Gao ;Rongzhang,Chen ;Xiaodong,Wu ;Yanan,He ;Qian,Guo ;Xin,Zhang ;Qiang,Li （Department of Pulmonary and Critical Care Medicine \'(1)\' ; Shanghai General Hospital [2] ; Shanghai Jiao Tong University School of Medicine [3] ; Shanghai [4] ; 201620 [5] ; China; Department of Pulmonary and Critical Care Medicine [6] ; Shanghai East Hospital [7] ; Tongji University [8] ; 200120 [9] ; China. [10] ; People\'s Liberation Army Joint Logistic Support Force 920th Hospital [11] ; China. Electronic address: derekzhang2008@163.com. [12] ; China. Electronic address: liqressh1962@163.com. [13]）

出处： Cryobiology

关键词： Animal model;Chronic obstructive pulmonary disease;Cryo-balloon;Targeted lung denervation

摘要： Targeted lung denervation (TLD) is a pulmonary interventional procedure for COPD that aims to disrupt parasympathetic nerve input to the lung to reduc ...

作者： Hui-Rong,Chen ;Ru-Hui,Tian ;Peng,Li ;Hui-Xing,Chen ;Shu-Jie,Xia ;Zheng,Li （Department of Andrology, The Center for Men\'s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China. \'(1)\'）

出处： Asian journal of andrology

关键词： erectile dysfunction;estradiol;organic etiology;testosterone;young

摘要： Erectile dysfunction attributable to testosterone deficiency is less common in young males, and the effect of estradiol on erectile function in eugona ...

作者： Jian,Zhang ;Meihua,Zhang ;Huijie,Zhao ;Xun,Xu （Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai 200080, China; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200080, China; National Clinical Research Center for Eye Diseases, Shanghai 20080, China; Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai 20080, China. \'(1)\' ; Maternal and Child Health Care Hospital of Shandong Province, Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Jinan 250002, PR China. [2] ; NCI-Frederick National Laboratory, Laboratory of Cellular and Development Signaling, Frederick, MD 21702, USA. Electronic address: huijie.zhao@nih.gov. [3] ; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai 200080, China; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200080, China; National Clinical Research Center for Eye Diseases, Shanghai 20080, China; Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai 20080, China. Electronic address: drxuxun@tom.com. [4]）

出处： Biochimica et biophysica acta. Molecular basis of disease P165794

关键词： Disease gene;Laplacian heat diffusion;Proliferative diabetic retinopathy

摘要： Diabetic retinopathy is a common complication of diabetes mellitus that causes pathogenic damage to the retina. Particularly, the proliferative diabet ...

作者： Miao,Yu ;Zhi-Xiao,Fang ;Wei-Wei,Wang ;Ying,Zhang ;Zhi-Lei,Bu ;Meng,Liu ;Xin-Hua,Xiao ;Zi-Lu,Zhang ;Xing-Ming,Zhang ;Yang,Cao ;Ying-Ying,Wang ;Hu,Lei ;Han-Zhang,Xu ;Yun-Zhao,Wu ;Wei,Liu ;Ying-Li,Wu （Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. \'(1)\' ; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic MedicineChemical Biology Division of Shanghai Universities E-Institutes, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. [2] ; Department of Hematology, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. [3] ; Department of Transfusion Medicine, Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. [4] ; Department of Hematology, The Third Affiliated Hospital of Soochow University, The First People\'s Hospital of Changzhou, Changzhou, 213003, China. [5] ; Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. bsjys@shsmu.edu.cn. [6] ; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic MedicineChemical Biology Division of Shanghai Universities E-Institutes, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. wuyingli@shsmu.edu.cn. [7]）

出处： Acta pharmacologica Sinica

关键词： AML;AMPKα;Compound C;FLT3-ITD;USP10;Wu-5;crenolanib;metformin

摘要： The kinase FLT3 internal tandem duplication (FLT3-ITD) is related to poor clinical outcomes of acute myeloid leukemia (AML). FLT3 inhibitors have prov ...