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作者: 彭志海;周崇治;张放;凌云;唐华美;裘国强;柏邵春;刘万清;贺林 (上海市第一人民医院普通外科,上海,200080 中国科学院上海生物科学研究所,上海,200031)

出处: 中华医学杂志(英文版) 2002 No.10 P1529-1532

关键词: 散发性结直肠癌;20号染色体;杂合缺失

摘要: 目的抑癌基因的杂合缺失被认为是结直肠癌形成的关键步骤之一,本研究利用微卫星DNA标记杂合缺失分析法对散发性结直肠癌20号染色体杂合缺失情况进行研究, 并探讨其意义.方法 83例结直肠癌病人的肿瘤及正常组织的DNA,经PCR反应后,以ABI Pr ism 377自动荧光测序仪进行电泳,以GeneSca ...

作者: Zhou CZ;Peng ZH;Zhang F;Qiu GQ;He L (Department of General Surgery, Shanghai First People Hospital, 85 Wujin Road, Shanghai 200080, China.)

出处: World J Gastroenterol 2002 Vol.8 No.4

摘要: AIM: The loss of heterozygosity (LOH) on tumor suppressor genes is believed to play a key role in carcinogenesis of colorectal cancer. In this study, ...

作者: Fan Y.;Wang F.;Xu X.;Zhang X.;Huang Q. (Department of Ophthalmology, Shanghai First People\'s Hospital, Shanghai 200080, China Department of Central Laboratory, Shanghai First People\'s Hospital, Shanghai 200080, China)

出处: Fudan University Journal of Medical Sciences 2002 Vol.29 No.3 P161-164

摘要: PurPose: To investigate whether the recombined plasmids that encoding vascular endothelial growth factor 165 (VEGF165) cDNA in an sense of antisense o ...

作者: Peng Z.-H.;Zhu Z.-C.;Xu D.;Xia Q.;Qiu Z.-J.;Li K. (Ctr. of Organ Transplant./Research, Department of General Surgery, Shanghai First People\'s Hospital, Shanghai 200080, China)

出处: Fudan University Journal of Medical Sciences 2002 Vol.29 No.2 P132-134,153

摘要: Purpose: To invesagate the surgical techniques, clinical experiences and therapeutic effects of combined liver-kidney transplantation(CLKT). Methods: ...

作者: (Department of General Surgery, Shanghai First People Hospital,Shanghai 200080, China Shanghai Institutes for Biological Science, Chinese Academy of Science, Shanghai 200031, China)

出处: 世界胃肠病学杂志(英文版) 2002 No.4

关键词: colon cancer;sporadic colorectal cancer;statistical significance;colorectal tumorigenesis;tumor suppressor genes;loss of heterozygosity;colorectal carcinoma

摘要: AIM: The loss of heterozygosity (LOH) on tumorsuppressor genes is believed to play a key role incarcinogenesis of colorectal cancer, In this study, we ...

作者: Zhao Y;Wang F;Li Y;Zhang Y;Zhang G (Department of Neurology, Shanghai First People\'s Hospital, Shanghai 200080, China)

出处: Chinese Journal Of Medical Genetics 2002 Vol.19 No.2 P130-133

关键词: AGZY83-a cells;Cell transplantation;Gene therapy;Tissue-plasminogen activator

摘要: Objective: To detect the expressing levels of human tissue-plasminogen activator(t-PA) in AGZY83-a cells transfected with pcDNA3.1(+) t-PA in vivo and ...

作者: Zou H.;Zhang X.;Xu X.;Wang W.;Li G.;Yu H. (Department of Ophthalmology, Shanghai First People\'s Hospital, Shanghai 200080, China.)

出处: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2002 Vol.38 No.12 P744-746

摘要: OBJECTIVE: To investigate the morbidities of low vision and blindness and the leading cause of blindness in residents aged >or= 60 years in Beixinjing ...

作者: Tan Y.;Yang Y.;Zhang Z.;Zhang X.;Zhang Z.;Liu Y. (Department of Endocrinology and Metabolism, Zhongshan Hospital, Medical College of Fudan University, Shanghai 200032, China Department of Pathology, Fudan University, Shanghai 200032, China Institute of Biochemical, Chinese Acadamy of Sciences, Shanghai 200032, China Institute of Liver Cancer, Fudan University, Shanghai 200032, China Department of Endocrinology and Metabolism, Shanghai First People\'s Hospital, Medical College of Fudan University, Shanghai 200032, China)

出处: Chinese Medical Journal 2002 Vol.115 No.3 P384-388

关键词: Area postrema;Interdigestive migrating motor complex;Medulla oblongata;Motilin

摘要: Objective. To determine the effect of the area postrema (AP) of the medulla oblongata on gastrointestinal interdigestive migrating motor complex (MMC) ...

作者: Zou H.;Wang X.;Zhang X. (Department of Ophthalmology, Shanghai First People\'s Hospital, Shanghai 200080, China)

出处: Chinese Ophthalmic Research 2002 Vol.20 No.2 P166-169

摘要: Objective: To analyze the acute vitreous change after episcleral buckling surgery for rhegmatogenous retinal detachment. Methods: Clinical and ultraso ...

作者: Zou H.;Zhang X.;Xu X.;He Z. (Department of Ophthalmology, Shanghai First People\'s Hospital, Shanghai 200080, China.)

出处: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2002 Vol.38 No.10 P580-583

摘要: OBJECTIVE: To investigate the recent incidence and related risk factors of rhegmatogenous retinal detachment (RD) in Chinese people. METHODS: This inc ...

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