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作者: Su, Yunshua;Wang, Xiaolia,b;Li, Juna;Xu, Junmingc;Xu, LijunaCAaaDepartment of Cardiothoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China;bCancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China;cDepartment of General Surgery, Shanghai First People’s Hospital, Shanghai Jiaotong University, Shanghai, China)

出处: Drug Design, Development and Therapy 2015

关键词: Drug target;FHIT;Meta-analysis;Methylation;Odds ratio;Tumor suppressor gene

摘要: FHIT is a bona fide tumor-suppressor gene and its loss contributes to tumorigenesis of epithelial cancers including breast cancer (BC). However, the a ...

作者: Zhao, Li-Quna;Wen, Zu-Jiab;Wei, Yonga;Xu, Juana;Chen, Zhenga;Qi, Bao-Zhena;Wang, Zhi-MingcCAa;Shi, Yong-YongbCAb;Liu, Shao-WenaCAcaDepartment of Cardiology, Shanghai First People's Hospital Affiliated to, Shanghai JiaoTong University, Shanghai, 200080, China;bBio-X Institutes, Shanghai Jiao Tong University, Shanghai, 200030, China;cDepartment of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center and Shanghai Industrial Technology Institute (SITI), Shanghai, 201203, China)

出处: PLoS ONE 2015

摘要: Background: Atrial fibrillation(AF) is the most common arrhythmia in the adult population. The activated renin-angiotensin-aldosterone system (RAS) ha ...

作者: Yuan, Jina,b;Jiang, Honga,c;Mao, Xinjiea,d;Ke, Biliana,e;Yan, Wentaoa,d;Liu, Chea;Cintrón-Colón, Hector R.a,f;Perez, Victor L.a;Wang, JianhuaaCAaaDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, United States;bDepartment of Ophthalmology, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, China;cDepartment of Neurology, University of Miami, Miami, FL, United States;dSchool of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China;eDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai, China;fDepartment of Microbiology and Immunology, University of Miami, Miami, FL, United States)

出处: Eye and Contact Lens 2015

关键词: Corneal epithelial thickness;High magnification;Slitlamp biomicroscopy;Ultra-high optical coherence topography;Videography

摘要: Purpose: To demonstrate the use of the slitlamp photography and videography with extremely high magnifications for visualizing structures of the anter ...

作者: Zhao, Si-Jiea;Liu, YanaCAaaDepartment of Ophthalmology, Shanghai General Hospital Affiliated to Shanghai Jiaotong University, Shanghai, 200080, China)

出处: International Eye Science 2015

关键词: Carrier;Corneal endothelial cells;Seeder cells;Tissue engineering;Transplantation

摘要: Due to the serious shortage of donor cornea materials and the donor limit, clinical popularization of penetrating keratoplasty is severely restricted. ...

作者: Tian, Ruhuia,b;Yang, Shib;Zhu, Yongb;Zou, Shashab;Li, Penga,b;Wang, Junlonga;Zhu, Zijuea,b;Huang, Yiranb;He, Zupingc,dCAa;Li, Zhenga,bCAbaDepartment of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai, 20080, China;bDepartment of Urology, Renji Hospital, China;cState Key Laboratory of Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell Research Center, Renji Hospital, 1630 Dongfang Road, Shanghai, 200127, China;dShanghai Institute of Cancer, Shanghai, China)

出处: Cells Tissues Organs 2015

关键词: Angiogenesis;Ectopic grafting;Seminiferous tubule regeneration;Spermatogenesis;Vascular endothelial growth factor

摘要: Vascular endothelial growth factor (VEGF) plays fundamental roles in testicular development; however, its function on testicular regeneration remains ...

作者: Min · Wang/Wang M;Wei-Dong · Wu/Wu WD;Gui-Ming · Chen/Chen GM;Sheng-Long · Chou/Chou SL;Xue-Ming · Dai/Dai XM;Jun-Ming · Xu/Xu JM;Zhi-Hai · Peng/Peng ZH (Department of General Surgery, Shanghai General Hospital of Nanjing Medical University, Nanjing Medical University, Shanghai, China E-mail : jimwsy@sina.com.)

出处: Asian Pacific journal of cancer prevention : APJCP 2015

摘要: BACKGROUND: Central lymph node metastasis(CLNM) is common in papillary thyroid microcarcinoma (PTMC). The aim of this study was to define the pathohis ...

作者: Wang, Jun;Xia, Shu-Jie;Liu, Zhi-Hong;Tao, Le;Ge, Ji-Fu;Xu, Chen-Min;Qiu, Jian-Xin (Department of Urology, Shanghai First People's Hospital, Medical College of Shanghai Jiao Tong University, Shanghai, China)

出处: Asian Journal of Andrology 2015

关键词: meta-analysis;varicocele;varicocelectomy

摘要: Conventional meta-analyses have shown inconsistent results for the efficacy of various treatments of varicoceles. Therefore, we performed a multiple-t ...

作者: Gressner, O.;Fang, M.;Li, H.;Lu, L.;Gressner, A.;Gao, C. (1Wisplinghoff Medical Laboratories, Cologne Branch, Köln, Deutschland;2Department of Laboratory Medicine, Eastern Hepatobiliary Surgical Hospital, Second Military Medical University, Shanghai, China;3Eastern Hepatobiliary Surgical Hospital, Department of Laboratory Medicine, Shanghai, China;4Shanghai Jiaotong University School of Medicine, Department of Gastroenterology, Shanghai First People's Hospital, Shanghai, China;5Wisplinghoff Medical Laboratories, Berlin Branch, Berlin, Deutschland)

出处: Clinical Chemistry and Laboratory Medicine 2015

摘要: We propose a new methodology based on bilevel programming to remove additive white Gaussian noise from images. The lower-level problem consists of a p ...

作者: Wang, Shige;Chen, Yu;Li, Xiang (1State Key Laboratory of High Performance Ceramic and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Science, Shanghai; 200050, China;2Tin Ka Ping College of Science, University of Shanghai for Science and Technology, Shanghai; 200093, China;3Department of Breast-Thyroid Surrey, Shanghai First People Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai; 200080, China;4Second Affiliated Hospital of Chongqing Medical University, Chongqing; 400016, China)

出处: Advanced Materials 2015

摘要: MoS2 nanosheets and a doxorubicin (DOX)-containing poly (lactic-co-glycolic acid) (PLGA)/MoS2/DOX composite implant are successfully constructed based ...

作者: Zhang, Xian;Sha, Minglei;Yao, Yuting;Da, Jia;Jing, Dadao (Department of Geriatrics, Shanghai First People's Hospital, Shanghai 200080, P.R. China)

出处: Molecular medicine reports 2015

关键词: chronic heart failure;B-type-natriuretic peptide;apoptosis;long non-coding RNA LSINCT5;caspase-1/interleukin 1 beta signaling pathway

摘要: Chronic heart failure (CHF) is the final stage of various heart diseases, and is increasingly recognized as a major health problem in the elderly. Pre ...

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