作者： Wuping Bao MD^1,2;Xue Tian MD^1,2;Huijuan Hao BS¹;Yubiao Jin MD³;Xueqian Xie MD⁴;Dongning Yin BS¹;Yingying Zhang MD¹;Xi Chen MD⁵;Yishu Xue BS¹;Lei Han BS¹;Fu Yang MD⁵;Min Zhang MD¹CA （1 Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; 2 Wuping Bao and Xue Tian are joint first authors and have contributed equally to this work.; 3 Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; 4 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; 5 Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Annals of Allergy, Asthma & Immunology 2022 Vol.128 No.1 P68-77(e1)

摘要： Background The clinical significance of small airway dysfunction (SAD) determined with spirometry in patients with normal forced expiratory volume in ...

作者： Lifang Jin¹;Ruitao Wang²;Lingling Zhuang¹;Yubiao Jin³;Xing Sun²;Chao Jia¹;Lizhou Lin¹;Qiusheng Shi¹;Weituo Zhang⁴;Lianfang Du¹CA1 （1 Department of Medical Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 100 Haining Road, Building 3, Room 417, 200080, Shanghai, China; 2 Department of Breast-Thyroid-Vascular Surgery, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 100 Haining Road, 200080, Shanghai, China; 3 Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 100 Haining Road, 200080, Shanghai, China; 4 Shanghai Jiao Tong University, School of Medicine, 227 South Chongqing Road, 200025, Shanghai, China）

出处： European Radiology 2022 Vol.32 No.1 P630-638

关键词： Humans;Ultrasonography;Lymph node;Axilla;Breast neoplasms

摘要： Objectives This study aims to evaluate the whole axillary status of patients with breast cancer by lymphatic contrast-enhanced ultrasound (LCEUS). M ...

作者： Houshi Xu^1,2;Anke Zhang^1,2;Xiaying Han³;Yanning Li⁴;Zeyu Zhang²;Liying Song⁵;Wei Wang⁶CA1;Meiqing Lou¹CA2 （1 Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 200080, Shanghai, China; 2 Department of Neurosurgery, School of Medicine, Second Affiliated Hospital, Zhejiang University, Zhejiang, China; 3 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 New Songjiang Road, 200080, Shanghai, China; 4 Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; 5 Shanxi Medical University, 030001, Taiyuan, Shanxi, China; 6 Department of Urology, First Hospital of Shanxi Medical University, 030001, Taiyuan, Shanxi, China）

出处： Cancer Immunology, Immunotherapy 2022 Vol.71 No.3 P645-660

关键词： Gliomas;Immunotherapy;Immune activation;T cell;ITGB2;Biomarker

摘要： Purpose Glioma is the most common primary tumor in the brain, accounting for 81% of intracranial malignancies. Nowadays, cancer immunotherapy has bec ...

作者： Yang, Chao;Li, Peng;Li, Zheng （Department of Andrology, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China）

出处： Human Reproduction Update 2022 Vol.28 No.1 P30-50

关键词： male infertility;aromatase inhibitors;hypothalamic-pituitary-gonadal axis;spermatogenesis;hypogonadism;obesity;CYP19A1 polymorphisms.

摘要： BACKGROUND Infertility affects 15% of men and contributes to nearly half of all cases of infertility. Infertile men usually have impaired spermatogene ...

作者： Li, Chunlin¹;Li, Feng^1,2;Chen, Jinyuan¹;Wu, Hongmei²;Lin, Ying³;Chen, Canyu¹;Zhang, Peng²;Wang, Qiugen¹;Liu, Jing^1,2;Deng, Guoying¹ （1 Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China 2 School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China 3 Nursing Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201620, China）

出处： Materials & Design 2022 Vol.213

关键词： Atomic layer deposition;Fibrin dysfunction;Hemorrhage;Hemostatic materials;Hollow Al2O3 nanofibers

摘要： [Display omitted] • Aluminium oxides are processed into three-dimensional biomimetic hollow fibers for safe and effective hemostasis for the first tim ...

作者： Ziheng Wei;Fei Ge;Yanting Che;Si Wu;Xin Dong;Dianwen Song （Department of Orthopedics, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 201620, China School of Medicine, Shanghai University, Shanghai 200444, China School of Medicine, Shanghai University, Shanghai 200444, China Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA School of Medicine, Shanghai University, Shanghai 200444, China Department of Orthopedics, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 201620, China）

出处： Biomolecules 2022 Vol.12 No.41 P41

关键词： postmenopausal osteoporosis;sarcopenia;skeletal muscles;estrogen;metabolomics

摘要： Postmenopausal osteoporosis (PMOP) and sarcopenia are common diseases that predominantly affect postmenopausal women. In the occurrence and developmen ...

作者： Wei Cai;Junxun Zhang;Hong Zhou;Xiangxiao Li;Fangzhou Lou;Yang Sun;Zhenyao Xu;Jing Bai;Qianqian Yin;Zhikai Wang;Libo Sun;Xiaojie Cai;Sibei Tang;Yue Wu;Li Fan;Hong Wang;Honglin Wang;Qun Li （Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China Department of Immunology and Microbiology, Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China;Corresponding author. Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine (SJTU-SM), 280 Chongqing South Road, Shanghai 200025, PR China. Fax: +86 21 64660996. The Department of Cardiovascular Medicine, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Institute of Hypertension, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China;Corresponding author. The Department of Cardiovascular Medicine, Shanghai Key Laboratory of Hypertension Ruijin Hospital, Shanghai Institute of Hypertension Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China.）

出处： Genes and Diseases 2022 Vol.9 No.2 P562-575

关键词： Akt;DNA methyltransferase 1 (Dnmt1);FoxP3;Protein phosphatase 6 (Pp6);Regulatory T (Treg) cells;Stability

摘要： Regulatory T (Treg) cells constitute a dynamic population that is critical in autoimmunity. Treg cell therapies for autoimmune diseases are mainly foc ...

作者： Zhang, Qiuhong^1,2;He, Meijuan³;Zhang, Xiaodong²;Yu, Hongwei³;Liu, Jiawei²;Guo, Yi²;Zhang, Junmin¹;Ren, Xiangzhong¹;Wang, Han³;Zhao, Yanli² （1 International Joint Research Center for Molecular Science, College of Chemistry and Environmental Engineering, Shenzhen University 2 Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University 3 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine）

出处： Advanced Functional Materials 2022 P1

关键词： chemodynamic therapy;photodynamic therapy;protein nanomedicine;self‐protection;tumor microenvironment

摘要： While cytotoxic reactive oxygen species (ROS) play an important role in fighting cancer, developing an activable ROS‐generating system to achieve high ...

作者： Miao, Hanyuan¹;Zhou, Xiaohong²;Wang, Wei³;Jiang, Weiliang⁴;Jin, Tao¹ （1 School of Optical‐Electrical and Computer Engineering, University of Shanghai for Science and Technology 2 Ophthalmology, Children\'s Hospital of Fudan University, National Children\'s Medical Center 3 Research Department, Naval Medical Center of PLA 4 Shanghai General Hospital, Shanghai Jiaotong University School of Medicine）

出处： International Journal of Imaging Systems & Technology 2022 P1

关键词： K‐SVD algorithm;optical coherence tomography;piecewise orthogonal matching pursuit algorithm;speckle noise

摘要： An improved sparse representation algorithm is proposed for reducing speckle noise in optical coherence tomography (OCT) images. To reduce the diction ...

作者： Minchao Cai;Qing Yu;Jinfang Bao （Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Department of Nephrology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine）

出处： BMC Nephrology 2022 Vol.23 No.1 P1-4

关键词： Mitochondrial myopathy;Membranous nephropathy;mtDNA mutation

摘要： Background MtDNA 3243 A > G mutation leads to mitochondrial myopathies with predominant hyperlactatemia. Given the ubiquitous nature of mitochondria, ...