陈莲华
详细
作者: 徐典,魏薇,连明,陈莲华,李士通 (上海交通大学附属第一人民医院麻醉科)
出处: 上海医学 2019
关键词: 正压呼吸;单肺通气;动态顺应性;肺内分流;氧合;靶控通气
摘要: 目的评价依据肺动态顺应性(Cdyn)调节呼气末正压(PEEP)减少单肺通气肺内分流,改善氧合的效应。方法选取上海交通大学附属第一人民医院择期行胸外科手术需单肺通气(OLV)的患者30例,随机分为试验组和对照组,每组15例。试验组将4 cmH 2 O(1 cmH 2 O=0.098 kPa)作为初始P ...
作者: 黄勇,吴爽,李士通,魏薇,陈莲华 (上海交通大学附属第一人民医院麻醉科;复旦大学附属中山医院麻醉科)
出处: 国际麻醉学与复苏杂志 2019
关键词: 面肌;骨骼肌;面神经;诱发肌电位;罗库溴铵;烟碱型乙酰胆碱受体
摘要: 目的研究面神经支配的肌肉和肢体神经支配的肌肉对罗库溴铵的敏感性是否存在差异,探讨不同肌肉对罗库溴铵的敏感性差异是否与烟碱型乙酰胆碱受体(nicotinic acetylcholine receptor,nAChR)亚基有关,同时探索不同肌肉nAChR的表达差异是否与聚集蛋白(agrin)/低密度脂蛋 ...
作者: 侯瑞雪,王宏,陈莲华,裘毅敏,李士通 (上海交通大学附属第一人民医院麻醉科)
出处: 上海医学 2018
关键词: 麻醉深度;术后认知功能障碍;神经阻滞
摘要: 目的观察神经阻滞复合不同麻醉深度的全身麻醉对老年膝关节置换手术患者术后认知功能和苏醒质量的影响。方法纳入择期行膝关节置换手术的患者65例,年龄65~80岁,美国麻醉医师协会(ASA)分级Ⅰ或Ⅱ级,术前蒙特利尔认知评估量表(MoCA量表)评分>23分。随机将患者分为浅麻醉组[33例,脑电双频指数(BI ...
作者: 张建友,李士通,龚园,陈莲华 (上海交通大学附属第一人民医院麻醉科;扬州大学附属医院麻醉科)
出处: 上海医学 2018 第41卷 第3期 P139-144
关键词: 罗库溴铵;急性腹膜炎;腹直肌;肌肉松弛
摘要: 目的探讨急性腹膜炎对大鼠罗库溴铵腹肌肌肉松弛效应和腹直肌功能的影响。方法雄性Sprague-Dawley大鼠36只,体重220~250g,采用随机数字表法将大鼠分为假手术组、胃穿孔1h组、胃穿孔2h组,每组12只。参照文献制作胃穿孔急腹症模型,腹腔内注入气体并记录压力变化,绘制容量-压力曲线,完成后 ...
作者: 连明,陈莲华 (上海交通大学附属第一人民医院麻醉科,南京医科大学附属上海一院临床医学院)
出处: 上海医学 2018 第41卷 第4期 P248-252
关键词: 腹腔镜手术;动力学变化;通气策略;影响因素;术后肺部并发症;美国麻醉医师协会;呼吸;院内病死率
摘要: 腹腔镜在外科领域被广泛应用,具有创伤小、恢复快、住院时间短等优点。除此之外,腹腔镜手术在降低术后肺部并发症、术后转ICU率和院内病死率等方面,也比开腹手术更有优势[1]。临床实践表明,大多数美国麻醉医师协会(ASA)分级Ⅰ或Ⅱ级的患者能够很好地耐受腹腔镜手术和术中机械通气。然而,对于有基础心肺疾病的 ...
作者: Huang, LN (Huang, Lina);Chen, LH (Chen, Lianhua);Qiu, YM (Qiu, Yimin);Li, ST (Li, Shitong) (;[ 1 ] Shanghai Jiao Tong Univ, Sch Med, Affiliated Peoples Hosp 1, Dept Anesthesiol, Shanghai 201620, Peoples R China)
出处: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 2018 Vol.11 No.2 P753-763
关键词: Streptozotocin;diaphragm;extensor digitorum longus;soleus;diabetes
摘要: The study aimed to investigate the changes induced by diabetes in diaphragm (DIA), extensor digitorumlongus (EDL), and soleus (SOL) contractility and ...
作者: Ruixue Hou;Hong Wang;Lianhua Chen;Yimin Qiu;Shitong Li (1 Department of Anesthesiology, Shanghai General Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China,)
出处: Brain Behav 2018 Vol.8 No.2 Pe00910
关键词: general anesthesia;nerve block;postoperative cognitive dysfunction
摘要: Objectives Clinical observation, as well as randomized controlled trials, indicated an increasing rate of postoperative cognitive dysfunction (POCD) w ...
作者: Yun Wang;Hong Wang;Huijuan Wang;Xiao Zhao;Shitong Li;Lianhua Chen (Department of Anesthesiology, Shanghai General Hospital of Nanjing Medical University, Shanghai 201620, China.)
出处: Annals of translational medicine 2019 No.8 P171
关键词: Positive end-expiratory pressure (PEEP);dead space to tidal volume ratio (VD/VT);intrapulmonary shunt;pulmonary dynamic compliance (pulmonary Cdyn)
摘要: Background: The intraoperative lung protective effect of mechanical ventilation of different positive end-expiratory pressure (PEEP) levels on patient ...
作者: Hong Wang;Xiao Zhao;Wang Yun;Lian-Hua Chen;Shi-Tong Li (Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 20080, China. Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 20080, China. lishitong77@163.com.)
出处: Cellular and molecular neurobiology 2019
关键词: Acetylcholine receptors;Denervation;Human antigen R;Post-transcriptional mechanisms;p38 inhibitor
摘要: Previous studies reported that RNA-binding protein human antigen R (HuR) mediates changes in the stability of AChR β-subunit mRNA after skeletal muscl ...
作者: Gu, Minglu;Lian, Ming;Gong, Chao;Chen, Lianhua;LI, Shitong;Lu., Min (Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiaotong University Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.)
出处: Medicine 2019 Vol.98 No.21 Pe15624
摘要: Background: Endotracheal intubation (ETI) is a life-saving procedure taught to medical students. We examined the influence of the order of teaching ET ...