陈莲华
详细
作者: 吴爽,黄勇,邢怡安,陈莲华,李士通 (上海交通大学附属第一人民医院麻醉科)
出处: 现代生物医学进展 2020 第20卷 第2期 P209-213
关键词: 诱发肌电位;非去极化肌松药;肌肉特异性激酶;表皮生长因子受体
摘要: 目的:研究烟碱型乙酰胆碱受体在在面神经支配的口轮匝肌和躯体神经支配的腓肠肌运动终板处的表达差异及可能的原因。方法:分离SD大鼠的口轮匝肌和腓肠肌,通过免疫共沉淀技术计算口轮匝肌和腓肠肌肌肉特异性激酶(Muscle Specific Kinase,Mu SK)的表达以及MuSK磷酸化水平。对MuSK的 ...
作者: 肖蕴誉,陈莲华 (南京医科大学附属上海一院临床医学院;上海交通大学附属第一人民医院麻醉科南京医科大学附属上海一院临床医学院;上海交通大学附属第一人民医院麻醉)
出处: 国际麻醉学与复苏杂志 2020
关键词: 肺部超声;肺不张;机械通气;保护性肺通气
摘要: 肺部超声(lung ultrasound, LUS)作为加速康复外科中重要的辅助检查手段,可以对术中肺部情况做出快速、及时、无创评估。文章通过综述近年文献,总结LUS检查方法及典型超声图像。探讨利用LUS识别围手术期肺不张的可行性,以及肺不张的严重程度在超声图像下分级。重点论述超声引导下肺通气监测, ...
作者: 魏薇,连明,陈莲华,李士通 (上海交通大学附属第一人民医院麻醉科)
出处: 复旦学报(医学版) 2020
关键词: 气道;三维重建;机械通气;计算流体力学(CFD)
摘要: 目的探索计算流体力学(computational fluid dynamics,CFD)技术模拟机械通气状态下呼吸系统内部气流流动的可行性,为CFD技术应用于机械通气的气流流场模拟奠定基础。方法选取1名健康的中年男性志愿者进行头颈部加胸部MRI扫描,将获得的图像保存为DICOM格式导入Mimics1 ...
作者: 赵晓,陈莲华,王宏,刘琨 (上海交通大学附属第一人民医院麻醉科)
出处: 四川医学 2020
关键词: 利多卡因;舒芬太尼;呛咳;全身麻醉
摘要: 目的探讨利多卡因抑制舒芬太尼诱发呛咳反射的效果。方法选取2017年1月至2018年10月在我院行腹腔镜胆囊切除患者150例,随机双盲分为利多卡因组(n=74)和生理盐水组(n=76),两组均给予舒芬太尼诱导,其中观察组静脉输注利多卡因,对照组静脉输注等量0.9%氯化钠液,观察两组呛咳发生情况,检测给 ...
作者: Jing Xu;Yong Huang;Shitong Li;Lianhua Chen;Zhanggang Xue (a Department of Anesthesiology , Eye and ENT Hospital of Fudan University , Shanghai , China. b Department of Anesthesiology, Zhongshan Hospital , Fudan University , Shanghai , China. c Department of Anesthesiology, Shanghai General Hospital , Shanghai Jiao Tong University , Shanghai , China.)
出处: Neurological research 2019 P1-10
关键词: Acetylcholine receptor;gastrocnemius;nerve injury;orbicularis oris
摘要: Objectives: To observe the expression of nicotinic acetylcholine receptor (AChR) subunits in normal orbicularis oris and gastrocnemius muscles and to ...
作者:
出处: Journal of Surgical Research 2019 Vol.243 P130-142
关键词: Facial nerve injury;Matrix metalloproteinase 3;Neuromuscular junction;Nicotinic acetylcholine receptor;Synaptic plasticity
摘要: We previously demonstrated differential expression of nicotinic acetylcholine receptors (nAChRs) in the facial nerve-innervated orbicularis oris and s ...
作者: Wang H;Zhao X;Yun W;Chen LH;Li ST (1 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 20080, Shanghai, China)
出处: Cellular And Molecular Neurobiology 2019 Vol.39 No.7 P1029-1037
关键词: Acetylcholine receptors;Denervation;Human antigen R;Post-transcriptional mechanisms;p38 inhibitor
摘要: Previous studies reported that RNA-binding protein human antigen R (HuR) mediates changes in the stability of AChR β-subunit mRNA after skeletal muscl ...
作者: Chao Gong;Shitong Li;Xiaojing Huang;Lianhua Chen (Affiliation 1 Department of Anesthesiology, Shanghai General Hospital of Nanjing Medical University, Nanjing Medical University, Shanghai, China.)
出处: PeerJ 2020 Vol.8 No.7 Pe9441
关键词: Diastolic function;Transesophageal echocardiography (TEE);Sevoflurane;Transversus abdominis plane block and rectus sheath block (TAPB and RSB)
摘要: Background Diastolic dysfunction, an early manifestation and clinical symptom of heart failure with preserved ejection fraction, can be influenced by ...
作者: Wei, Wei;Lian, Ming;Chen, Lianhua;Li, Shitong (Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong Univeristy, Shanghai, 201620, China)
出处: Fudan University Journal of Medical Sciences 2020 Vol.47 No.4 P531
摘要: Objective: To explore the feasibility of computational fluid dynamics (CFD) technology to simulate the flow of airflow inside the respiratory system u ...
作者: Yu, F.;Le, Z.-S.;Chen, L.-H.;Qian, H.;Yu, B.;Chen, W.-H. (a Department of Rehabilitation, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100, Haining Road, Shanghai, 200080, China; b Department of Neurosurgery, Fuyang Hospital of Anhui Medical University, Fuyang, China; c Department of Rehabilitation, Shanghai Fifth Rehabilitation Hospital, Shanghai, China)
出处: Journal of Computational Biology 2020 Vol.27 No.6 P888-903
关键词: Gene Ontology;miRNA-target;Parkinson\'s disease;pathway;protein-protein interaction;rotenone
摘要: To explore the expression changes of genes and the pathological processes-related genetic information in Parkinson\'s disease (PD) model induced by ro ...