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  • The study on the method and feasibility of computational fluid dynamics (CFD) to simulate the flow field characteristics of lower airway during mechanical ventilation

  • 【作者】Wei, Wei;Lian, Ming;Chen, Lianhua;Li, Shitong
  • 【作者单位】Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong Univeristy, Shanghai, 201620, China
  • 【出处】Fudan University Journal of Medical Sciences
  • 【年份】2020
  • 【卷号】Vol.47 No.4
  • 【页码】531
  • 【ISSN】1672-8467
  • 【摘要】Objective: To explore the feasibility of computational fluid dynamics (CFD) technology to simulate the flow of airflow inside the respiratory system under mechanical ventilation, and lay a foundation for the simulation of the flow field of CFD applied to mechanical ventilation. Methods: A healthy middle-aged male volunteer was selected for head and neck and chest MRI scans. The obtained images were saved as DICOM format and imported into Mimics software to construct a three-dimensional airway model. The CFD simulation calculation was performed by ANSYS 14. 5 software to dynamically analyze the flow field variation inside the mechanical ventilation airway. Results: The airway 3D model was successfully constructed based on MRI image data. The inlet boundary conditions of different flow rates were applied to the CFD simulation. The flow velocity distribution, wall pressure distribution, flow field line variation and local wall shear stress were analyzed. Conclusion: Based on medical imaging data, the airway was reconstructed in three dimensions. Through the CFD simulation of the model, it is found that the inlet flow velocity is positively correlated with the airway structure, wall pressure and wall shear stress. Turbulence can be observed at the bifurcation of airway when the inlet flow velocity is high.
  • 【文献类型】外文期刊

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