作者： Li, J.;Wang, P.;Yu, S.;Zheng, Z.;Xu, X. （a Department of Ophthalmology, Shanghai First People\'s Hospital Affiliated Shanghai, Jiao Tong University, Shanghai, China; b Department of Ophthalmology, Lishui City Center Hospital, Zhejiang Province, China）

出处： Molecular Vision 2012 Vol.18 No.250 P2371-2379

关键词： HIGH GLUCOSE;DIABETIC-RETINOPATHY;ENDOPLASMIC-RETICULUM;CA2+ OSCILLATIONS;DEATH;FAS;CALCINEURIN;EXPRESSION

摘要： Purpose: Hyperglycemia-induced vascular cell apoptosis is a seminal early event in diabetic retinopathy. Prolonged hyperglycemia is known to increase ...

作者： Yang, C.;Wen, Y.;Li, H.;Zhang, D.;Zhang, N.;Shi, X.;Jiang, B.;Ma, X.;Yang, P.;Tang, H.;Peng, Z.;Yang, Y. （a Department of Anal-Colorectal Surgery, Ningxia Medical University, Yinchuan 750004, China; b Department of Pathology, Ningxia Medical University, Yinchuan 750004, China; c Department of General Surgery, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai 200080, China; d Department of Pathology, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai 200080, China）

出处： Oncology Reports 2012 Vol.27 No.1 P135-142

关键词： Gastric cancer;Immunohistochemistry;Minichromosome maintenance 2;Prognosis;Survival analysis

摘要： We examined the expression of minichromosome maintenance 2 (MCM2) in gastric cancer and adjacent normal tissues and estimated the possible value of MC ...

作者： Wang, H.;Cui, X.;Gu, Q.;Chen, Y.;Zhou, J.;Kuang, Y.;Wang, Z.;Xu, X. （a Department of Ophthalmology, Shanghai First People\'s Hospital, Affiliate of Shanghai Jiaotong University, Shanghai, China; b Department of Medical Genetics, E-Institutes of Shanghai Universities, Shanghai Jiaotong University School of Medicine, Shanghai, China; c Shanghai Research Center for Model Organisms, Shanghai, China）

出处： Molecular Vision 2012 Vol.18 No.108-09 P1021-1030

关键词： SHORT-CHAIN DEHYDROGENASE/REDUCTASE;VERTEBRATE RETINA;VISUAL CYCLE;PIGMENT EPITHELIUM;REDUCTASE-ACTIVITY;CYTOCHROME-C;IN-VIVO;METABOLISM;RDH12;RPE65

摘要： Purpose: To investigate whether retinol dehydrogenase 13 (RDH13) can protect the retina from acute light-induced damage. Methods: We generated Rdh13 k ...

作者： Liu, Y.;Tao, X.;Fan, L.;Jia, L.;Gu, C.;Feng, Y. （a Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, 419 Fang Xie Road, Shanghai 200011, China; b Department of Obstetrics and Gynecology, Shanghai First People\'s Hospital, Jiao Tong University, Shanghai 200080, China; c Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai 200011, China）

出处： Molecular Medicine Reports 2012 Vol.6 No.5 P1050-1056

关键词： Lentivirus;Mediator complex subunit 19;Ovarian cancer;Proliferation

摘要： Ovarian cancer causes more deaths than any other type of female reproductive cancer. The development of new therapeutic approaches is required due to ...

作者： Wei, Y.;Zhang, Z.;Liao, H.;Wu, L.;Wu, X.;Zhou, D.;Xi, X.;Zhu, Y.;Feng, Y. （a Department of Obstetrics and Gynecology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China; b First Maternal and Fetal Care Hospital, Tongji University, Shanghai, China; c Tengzhou Central People\'s Hospital, Tengzhou, Shandong, China）

出处： Oncology Reports 2012 Vol.27 No.2 P504-510

关键词： Endometrial cancer;Estrogen;GPR30;Notch;Proliferation

摘要： To elucidate the mechanisms of nuclear estrogen receptor (ER)-mediated and G protein-coupled receptor 30 (GPR30)-mediated signaling in the regulation ...

作者： Liao, H.;Zhou, Q.;Gu, Y.;Duan, T.;Feng, Y. （a Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, 536 Changle Road, Shanghai 200080, China; b Department of Obstetrics and Gynecology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China）

出处： Oncology Reports 2012 Vol.27 No.6 P1873-1878

关键词： Angiogenesis;Luteinizing hormone;Metformin;Slit2;Vascular endothelial growth factor

摘要： High levels of gonadotropin are a risk factor for ovarian cancer development. Aberrant gonadotropin levels benefit tumor angiogenesis, but the detaile ...

作者： Yao, H.-L.;Gao, F.-H.;Li, Z.-Z.;Wu, H.-X.;Xu, M.-D.;Zhang, Z.;Dai, Q.-Y. （a Cardiac Vascular Unit, Shanghai First People\'s Hospital, Shanghai Jiao-Tong University, Shanghai 200080, China; b No. 3 People\'s Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 201900, China）

出处： Molecular and Cellular Biochemistry 2012 Vol.366 No.1-2 P355-362

关键词： Angiotensin II;Monocyte chemotactic protein-1;Proliferation;Vascular smooth muscle cell

摘要： Abnormal vascular smooth muscle cells proliferation is the pathophysiological basis of cardiovascular diseases, such as hypertension, atherosclerosis, ...

作者： Zuowei Li;Ming Luo;Jianxin Qiu( jasonqiu@medmail.com.cn);Yong Liu;Yu Fan;Jahr, Fay M.;Cai, Junchao;Terasaki, Paul I. （1 Department of Urology and Renal Transplantation, Shanghai first people\'s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China 2 Terasaki Foundation Laboratory, 11570 W. Olympic Blvd., Los Angeles, CA 90064, USA）

出处： Experimental & Clinical Transplantation 2012 Vol.10 No.3 P239-242

关键词： HLA ANTIBODIES;FOLLOW-UP;MICA;REJECTION;ANTIGEN;TRANSPLANTATION;DONOR

摘要： Objectives: To determine the prevalence, allele specificity, and intensity of anti-MICA antibodies in long-term renal graft recipients and to investig ...

作者： Liu, Y.;Tao, X.;Jia, L.;Cheng, K.W.;Lu, Y.;Yu, Y.;Feng, Y. （a Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, 419 Fang Xie Road, Shanghai 200011, China; b Department of Systems Biology, University of Texas, M. D. Anderson Cancer Center, Houston, TX 77054, United States; c Department of Obstetrics and Gynecology, Shanghai First People\'s Hospital, Jiao Tong University, Shanghai 200080, China）

出处： Molecular Medicine Reports 2012 Vol.6 No.5 P1006-1012

关键词： Apoptosis;Autophagy;Extracellular signal-regulated kinases;Ovarian cancer;Proliferation;RAB25

摘要： RAB25 belongs to the Rab family of small GTPases and is implicated in the development of various types of human cancer. To evaluate the role of RAB25 ...

作者： Liao, H.;Zhou, Q.;Zhang, Z.;Wang, Q.;Sun, Y.;Yi, X.;Feng, Y. （a Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China; b Department of Obstetrics and Gynecology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China; c Obstetrics and Gynecology Hospital, Fudan University, 419 Fang Xie Road, Shanghai 200011, China）

出处： Oncology Reports 2012 Vol.27 No.6 P1918-1924

关键词： Gonadotrophin;Nuclear factor-erythroid 2;Ovarian epithelial carcinoma;Reactive oxygen species;Sex-steroid hormones

摘要： Aberrant nuclear factor-erythroid 2 (NRF2) expression correlates with tumor development. We investigated NRF2 expression in ovarian epithelial carcino ...