作者： Wang, Hong;Yuan, Qingqing;Sun, Min;Niu, Minghui;Wen, Liping;Fu, Hongyong;Zhou, Fan;Chen, Zheng;Yao, Chencheng;Hou, Jingmei;Shen, Ruinan;Lin, Qisheng;Liu, Wenjie;Jia, Ruobing;Li, Zheng;He, Zuping （a State Key Laboratory of Oncogenes and Related Genes, Renji- Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China; b Department of Andrology, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai, 200080, China; c Shanghai Institute of Andrology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Shangdong Road, Shanghai, 200001, China; d Shanghai Key Laboratory of Assisted Reproduction and Reproductive Genetics, Shanghai, 200127, China; e Shanghai Key Laboratory of Reproductive Medicine, Shanghai, 200025, China）

出处： SCIENTIFIC REPORTS 2017 Vol.7

关键词： GERMLINE STEM-CELLS;ANDROGEN RECEPTOR;NEUROTROPHIC FACTOR;FUNCTIONAL MATURATION;SIGNALING PATHWAYS;DROSOPHILA OVARY;GROWTH-FACTOR;SELF-RENEWAL;MICE LACKING;SPERMATOGENESIS

摘要： Sertoli cells are essential for regulating normal spermatogenesis. However, the mechanisms underlying human Sertoli cell development remain largely el ...

作者： Wang, J.;Liu, X.;Yan, C.;Liu, J.;Wang, S.;Hong, Y.;Gu, A.;Zhao, P. （a Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; b Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; c Xuzhou Maternity and Child Health Care Hospital, Xuzhou Medical University, Xuzhou, China; d Department of Intensive Care Unit, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; e State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; f Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China）

出处： OncoTargets and Therapy 2017 Vol.10 P4251-4260

关键词： Apoptosis;Glioblastoma;Invasion;LEF1-AS1;LncRNA;Proliferation

摘要： Objectives: The long-noncoding RNAs (lncRNAs) are identified as new crucial regulators of diverse cellular processes in glioblastoma (GBM) tissues. Ho ...

作者： Xiuxiu Li;Jun Wen;Jingjing Jiang;Xin Zhao;Tingting Zhou;Guorong Fan （1 Shanghai Key Laboratory for Pharmaceutical Metabolite Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China 2 Department of Pharmaceutical Analysis, School of Pharmacy, Second Military Medical University, No. 325 Guohe Road, Shanghai 200433, China 3 Department of Pharmaceutical Analysis, School of Pharmacy, China Pharmaceutical University, No. 24 Tong Jia Xiang, Nanjing 210009, China 4 Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, No. 100 Haining Road, Shanghai 200025, China 5 School of Medicine, Tongji University, No. 1239 Siping Road, Shanghai 200092, China）

出处： Molecules 2017 Vol.22 No.5 P693

关键词： chlorin e6-C15-monomethyl ester;HPLC-UV;pharmacokinetics;photosensitizer

摘要： Chlorin e6-C15-monomethyl ester (CMME) is a novel photosensitizer, which is synthetized from the degradation products of silkworm excrement. Preclinic ...

作者： Jie-wen Lei;Xiao-yu Ji;Jun-feng Hong;Wan-bin Li （Jie-wen Lei ( Eastern Hepatobiliary Surgery Hospital (EHBH), Second Military Medical University, Department of Ultrasound, Shanghai, China) ; Xiao-yu Ji ( Second Military Medical University, People’s Liberation Army Military Academy, Shanghai, China) ; Jun-feng Hong ( Eastern Hepatobiliary Surgery Hospital (EHBH), Second Military Medical University, Department of Ultrasound, Shanghai, China) FuZhou General Hospital (Dongfang Hospital), Xiamen University, Department of Ultrasound, Fuzhou, China) ; Wan-bin Li ( Shanghai First People’s Hospital, Department of Ultrasound, Shanghai, China)）

出处： BMC Gastroenterology 2017 Vol.17 No.1 P1-7

关键词： Hepatocellular carcinoma;Hepatectomy;Posthepatectomy liver failure;Liver stiffness measurement;Hepatitis B

摘要： Background It is essential to accurately predict Postoperative liver failure (PHLF) which is a life-threatening complication. Liver hardness measureme ...

作者： Huanqiang Zhao, Fupin Hu, Han Yang, Baixing Ding, Xiaogang Xu, Chunyan He, Zelin Cui, Wen Shu, Qingzhong Liu （Affiliations 1 Department of Clinical Laboratory, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. 2 Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.）

出处： Future microbiology 2017 Vol.12 No.13 P1181-1199

关键词： SprC;Staphylococcus aureus;iTRAQ;proteomics;sRNA.

摘要： Aim: To explore the complete gene networks regulated by small RNA SprC and its targets in Staphylococcus aureus. Materials & methods: The isobaric tag ...

作者： Yang, Bin;Li, Zheng-Liang;Gao, Yi;Yang, Ya-Ying;Zhao, Wei （a Medical Imaging Department, First Affiliated Hospital, Dali University, Dali, Spain; b Department of Cardiology, Shanghai General Hospital, China; c Medical Imaging Department, First Affiliated Hospital, Kunming Medical University, Kunming, China）

出处： MEDICINE 2017 Vol.96 No.11

关键词： CARE kV;chest;iterative reconstruction;radiation dosage;tomograph;x-ray computed

摘要： Background: To investigate the radiation dose and image quality for iterative reconstruction combined with the CARE kV technique in chest computed tom ...

作者： Ding, X.;Xu, Y.;Wang, Y.;Li, X.;Lu, C.;Su, J.;Ma, Y.;Chen, Y.;Yin, Y.;Zhang, L.;Wu, Y.;Jin, Y.;Zheng, L.;Xu, S.;Zhu, X.;Ma, J.;Yu, L.;Jiang, J.;Zhao, N.;Yan, Q.;Greenberg, A.S.;Huang, Q.;Ren, Q.;Sun, H.;Gu, M.;Zhao, L.;Huang, Y.;Wu, Y.;Qian, C.;Peng, Y. （a Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, 100 Haining Rd, Shanghai, 200080, China; b Obesity and Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, United States; c Department of Internal Medicine, Sijing Hospital, 389 Sitong Rd, Shanghai, 201601, China; d Department of Chronic Disease Prevention and Control, Sijing Community Health Service Center of Songjiang District, 108 North Jiangchuan Rd, Shanghai, 201601, China; e Shanghai Pudong New Area Center for Disease Control and Prevention, 3039 Zhangyang Rd, Shanghai, 200136, China; f Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA 02111, United States）

出处： International Journal of Endocrinology 2017 Vol.2017

摘要： The mechanisms facilitating hypertension in diabetes still remain to be elucidated. Nonalcoholic fatty liver disease (NAFLD), which is a higher risk f ...

作者： Xin Zhao;Jingjing Jiang;Guang Yang;Jie Huang;Guoping Yang;Guangwei He;Zhaoxing Chu;Taijun Hang;Guorong Fan （1 Department of Pharmaceutical Analysis, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China 2 Shanghai Key Laboratory for Pharmaceutical Metabolite Research, School of Pharmacy, Second Military Medical University, Shanghai 200433, China 3 Center of Clinical Pharmacology, Third Xiangya Hospital, Central South University, Changsha 410013, Hunan, China 4 Hefei Institute of Pharmaceutical Industry Co., Ltd.,Wenshan Road, Hefei 230601, China 5 Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, No. 100 Haining Road, Shanghai 200080, China 6 Laboratory of Drug Metabolism & Pharmacokinetics, School of Medicine, Tongji University, No. 1239 Siping Road, Shanghai 200092, China）

出处： Molecules 2017 Vol.22 No.3 P494

关键词： human urine;macroporous resin;metabolite;online SPE-HPLC-MSn;PHPLC;Pyragrel

摘要： Pyragrel, a new anticoagulant drug, is derived from the molecular combination of ligustrazine and ferulic acid. Pyragrel showed significant inhibitory ...

作者： Yang, Guang;Zhao, Xin;Fan, Guorong （1 Department of Pharmaceutical Analysis, School of Pharmacy, Second Military Medical University, No. 325 Guohe Road, Shanghai 200433, PR China 2 No.208 Hospital of Chinese People’s Liberation Army, Changchun 130062, PR China 3 Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, No. 100 Haining Road, Shanghai 200025, PR China 4 Department of Pharmaceutical Analysis, School of Pharmacy, China Pharmaceutical University, No. 24 Tong Jia Xiang, Nanjing 210009, PR China 5 Shanghai Key Laboratory for Pharmaceutical Metabolite Research, School of Pharmacy, Second Military Medical University, No. 325 Guohe Road, Shanghai 200433, PR China 6 School of Medicine, Tongji University, No. 1239 Siping Road, Shanghai 200092, PR China）

出处： Journal of Chromatography A 2017 Vol.1518 P34-45

关键词： CAD charged aerosol detection;Chemometrics;Fingerprint;HCA Hierarchical Cluster Analysis;Hierarchical Cluster Analysis;M. biondii Magnolia biondii Pamp;Magnolia biondii Pamp.;PCA Principal Component Analysis;Principal Component Analysis;PSE pressurized solvent extraction;SA Similarity Analysis;SI Similarity Index;Similarity Analysis

摘要： Chromatographic fingerprint analysis has been widely used in quality control of herbal medicines, and Similarity Analysis (SA) as a well-established m ...

作者： Qin Jiang;Zimiao Luo;Yongzhi Men;Peng Yang;Haibao Peng;Ranran Guo;Ye Tian;Zhiqing Pang;Wuli Yang; （Affiliations 1 State Key Laboratory of Molecular Engineering of Polymers & Department of Macromolecular Science, Fudan University, Shanghai, 200433, PR China. 2 Key Laboratory of Smart Drug Delivery, Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, 201203, PR China. 3 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200433, PR China. 4 Key Laboratory of Smart Drug Delivery, Ministry of Education & PLA, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, 201203, PR China. Electronic address: zqpang@fudan.edu.cn. 5 State Key Laboratory of Molecular Engineering of Polymers & Department of Macromolecular Science, Fudan University, Shanghai, 200433, PR China. Electronic address: wlyang@fudan.edu.cn.）

出处： Biomaterials 2017 Vol.143 P29-45

关键词： Melanin nanoparticles;Photoacoustic imaging;Photothermal therapy;Red blood cells

摘要： Photothermal therapy (PTT) has represented a promising noninvasive approach for cancer treatment in recent years. However, there still remain challeng ...