作者： Zhao S.;Mei K.;Qian L.;Yang Y.;Liu W.;Huang Y.;Zhang C.;Sun X.;Liu C.;Li B.;Gao F.;Cai J.;Ni J. （a Department of Radiation Medicine, Second Military Medical University, Shanghai, PR China b Department of Hematology, Navy General Hospital, Beijng, PR China c Department of Diving Medicine, Second Military Medical University, Shanghai, PR China d Zhejiang Provincial Center for Disease Control and Prevention, Zhejiang, PR China e Department of Radiology, Shanghai First People's Hospital, Shanghai, PR China f Sanhu Zhao and Ke Mei contributed equally to this work null Corresponding Author Dr. Jianming Cai and Dr. Jin Ni Department of Radiation Medicine, Faculty of Naval Medicine, Second Military Medical University, Xiangyin Road, 200433, Shanghai (PR China) Tel. +86-21-81871101, Fax +86-21-81871101 E-Mail cjm882003@yahoo.com.cn (Cai JM) and E-Mail nijin2006@yahoo.com.cn (Ni J)）

出处： Cellular Physiology and Biochemistry 2013 Vol.32 No.3 P549-560

关键词： Aplastic anemia;Hydrogen-rich solution;Peripheral blood;Bone marrow;Cytokine

摘要： Background: Aplasitc anemia (AA) is a bone marrow failure syndrome characterized by an immune-mediated destruction of hematopoietic stem cells. Though ...

作者： Zhou, Shuyan;Min, Xue;Dou, Hongjing;Sun, Kang;Chen, Chun-Yen;Chen, Chao-Tsen;Zhang, Zhaofeng;Jin, Yuqing;Shen, Zunli （1 The State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China 2 Department of Chemistry, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei, 10617 Taiwan, Republic of China 3 Department of Plastic and Reconstructive Surgery, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, P. R. China）

出处： Chemical Communications 2013 Vol.49 No.82 P9473-9475

摘要： Glucose-responsive nanogels based on dextran and poly(3-acrylamidophenylboronic acid) (PAAPBA) were fabricated by a facile self-assembly assisted (SAA ...

作者： Li, Q (Li, Qin);Xu, Y (Xu, Yuan);Li, XY (Li, Xiao-yu);Guo, YK (Guo, Yan-kun);Liu, GL (Liu, Gao-lin) （;[ 1 ] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 1, Dept Pharm, Shanghai 200080, Peoples R China）

出处： ACTA PHARMACOLOGICA SINICA 2013 Vol.34 P67

关键词： Rho-kinase;TAC;MI;myocardial fibrosis;TGF-beta 1-TAK1

作者： Liu, Y (Liu, Yan);Liu, H (Liu, Heng);Meyer, C (Meyer, Christoph);Li, J (Li, Jun);Nadalin, S (Nadalin, Silvio);Konigsrainer, A (Koenigsrainer, Alfred);Weng, HL (Weng, Honglei);Dooley, S (Dooley, Steven);ten Dijke, P (ten Dijke, Peter) （;[ 1 ] Heidelberg Univ, Med Fac Mannheim, Sect Mol Hepatol, Dept Med 2, D-68167 Mannheim, Germany [ 2 ] Leiden Univ, Med Ctr, Dept Mol Cell Biol, Canc Genom Ctr Netherlands, NL-2300 RC Leiden, Netherlands [ 3 ] Leiden Univ, Med Ctr, Ctr Biomed Genet, NL-2300 RC Leiden, Netherlands [ 4 ] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 1, Dept Gastroenterol, Shanghai 200080, Peoples R China [ 5 ] Univ Tubingen Hosp, Dept Gen Visceral Surg & Transplantat, D-72076 Tubingen, Germany [ 6 ] Univ Med Ctr Hamburg Eppendorf, Dept Hepatobiliary Surg & Visceral Transplantat, D-20246 Hamburg, Germany）

出处： JOURNAL OF BIOLOGICAL CHEMISTRY 2013 Vol.288 No.42 P30708-30719

关键词： ERK;Jak Kinase;Jun N-terminal Kinase (JNK);MAP Kinases (MAPKs);PI 3-kinase (PI3K);SMAD Transcription Factor;Liver Fibrosis

摘要： In fibrotic liver, connective tissue growth factor (CTGF) is constantly expressed in activated hepatic stellate cells (HSCs) and acts downstream of TG ...

作者： Liu, H (Liu, Hui);Zhu, JY (Zhu, Jingyi);Zhao, JL (Zhao, Jinglong);Zhang, GX (Zhang, Guixiang);Shi, XY (Shi, Xiangyang) （;[ 1 ] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Shanghai 201620, Peoples R China [ 2 ] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 1, Dept Radiol, Shanghai 200080, Peoples R China）

出处： JOURNAL OF CONTROLLED RELEASE 2013 Vol.172 No.1 PE37-E38

关键词： Computed tomography;PAMAM dendrimer;Gold nanoparticles;Targeting;Cancer cells

作者： Xie, H (Xie, Hui);Tan, JT (Tan, Jiu-ting);Wang, RL (Wang, Rui-lan);Meng, XX (Meng, Xiao-Xiao);Tang, X (Tang, Xue);Gao, S (Gao, Shan) （;[ 1 ] Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 1, Intens Care Unit, Shanghai 0086201620, Peoples R China）

出处： EXPERIMENTAL BIOLOGY AND MEDICINE 2013 Vol.238 No.9 P1062-1068

关键词： Paraquat;pulmonary fibrosis;epithelial-mesenchymal transition;hypoxia-inducible factor 1 alpha;transforming growth factor beta 1

摘要： It is commonly accepted that epithelial-mesenchymal transition contributes to fibrotic remodeling, but the molecular pathways involved in paraquat (PQ ...

作者： Tang, J (Tang, Jing);Heise, T (Heise, Tilman);Zhang, J (Zhang, Jian);Liu, GL (Liu, Gao-lin) （;[ 1 ] Shandong Jiaotong Univ, Sch Med, Shanghai Peoples Hosp 1, Dept Pharm, Shanghai 200080, Peoples R China [ 2 ] Med Univ S Carolina, Dept Biochem & Mol Biol, Charleston, SC 29425 USA [ 3 ] Shanghai Jiao Tong Univ, Dept Pathophysiol, Chinese Minist Educ, Key Lab Cell Differentiat & Apoptosis,Sch Med, Shanghai 200025, Peoples R China）

出处： ACTA PHARMACOLOGICA SINICA 2013 Vol.34 P132-133

关键词： human La protein;casein kinase II;hepatitis B virus;phosphorylation

作者： Jinbao Qin;Kangan Li;Chen Peng;Xiangxiang Li;Jiaying Lin;Kaichuang Ye;Xinrui Yang;Qingsong Xie;Zunli Shen;Yuqing Jin;Mier Jiang;Guixiang Zhang;Xinwu Lu （a Department of Vascular Surgery, Shanghai Ninth People's Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200011, PR China; b Department of Radiology, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, 100 Haining Road, Shanghai 200080, PR China; c College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, PR China; d Clinic for Gynecology, Charite-Universitatsmedizin Berlin, Berlin 12203, Germany; e Department of Neurosurgery, Cixi Municipal People's Hospital, Zhejiang Province 315300, PR China; f Department of Plastic and Reconstructive Surgery, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200080, PR China; g Vascular Center of Shanghai JiaoTong University, Shanghai 200011, PR China）

出处： Biomaterials 2013 Vol.34 No.21 P4914-4925

关键词： Cell;tracking;Adipose-derived;stem;cells;(ADSCs);Limb;ischemia;Iron;oxide;nanoparticles;Magnetic;resonance;imaging;(MRI)

摘要： Adipose-derived stem cells (ADSCs) exhibit tremendous potential for repair of ischemic diseases. However, studies on the fate, migration, differentiat ...

作者： Qian Chen;Kangan Li;Shihui Wen;Hui Liu;Chen Peng;Hongdong Cai;Mingwu Shen;Guixiang Zhang;Xiangyang Shi （a State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China; b Department of Radiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, PR China; c College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, PR China; d CQM-Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal）

出处： Biomaterials 2013 Vol.34 No.21 P5200-5209

关键词： Dendrimers;Gold;nanoparticles;Gadolinium;Cancer;cells;CT;imaging;MR;imaging

摘要： We report the synthesis and characterization of folic acid (FA)-modified multifunctional dendrimer-entrapped gold nanoparticles (Au DENPs) loaded with ...

作者： Wen, Shihui;Li, Kangan;Cai, Hongdong;Chen, Qian;Shen, Mingwu;Huang, Yunpeng;Peng, Chen;Hou, Wenxiu;Zhu, Meifang;Zhang, Guixiang( guixiangzhang@sina.com);Shi, Xiangyang( xshi@dhu.edu.cn) （1 College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, PR China 2 Department of Radiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, PR China 3 State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai 201620, PR China 4 CQM-Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal）

出处： Biomaterials 2013 Vol.34 No.5 P1570-1580

关键词： Dendrimers;Gold nanoparticles;Gadolinium;PEGylation;CT imaging;MR imaging

摘要： We report the synthesis, characterization, and utilization of gadolium-loaded dendrimer-entrapped gold nanoparticles (Gd–Au DENPs) for dual mode compu ...