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陈莲华

麻醉科

职称:主任医师、博导

陈莲华所有成果
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[外文期刊] Effect of Inhibiting p38 on HuR Involving in β-AChR Post-transcriptional Mechanisms in Denervated Skeletal Muscle.

作者:Hong Wang;Xiao Zhao;Wang Yun;Lian-Hua Chen;Shi-Tong Li (Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 20080, China. Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 20080, China. lishitong77@163.com.)

出处:Cellular and molecular neurobiology 2019

关键词:Acetylcholine receptors;Denervation;Human antigen R;Post-transcriptional mechanisms;p38 inhibitor

摘要:Previous studies reported that RNA-binding protein human antigen R (HuR) mediates changes in the stability of AChR β-subunit mRNA after skeletal muscl ...

作者:Yun Wang;Hong Wang;Huijuan Wang;Xiao Zhao;Shitong Li;Lianhua Chen (Department of Anesthesiology, Shanghai General Hospital of Nanjing Medical University, Shanghai 201620, China.)

出处:Annals of translational medicine 2019

关键词:Positive end-expiratory pressure (PEEP);dead space to tidal volume ratio (VD/VT);intrapulmonary shunt;pulmonary dynamic compliance (pulmonary Cdyn)

摘要:Background: The intraoperative lung protective effect of mechanical ventilation of different positive end-expiratory pressure (PEEP) levels on patient ...

作者:Huang, LN (Huang, Lina);Chen, LH (Chen, Lianhua);Qiu, YM (Qiu, Yimin);Li, ST (Li, Shitong) (;[ 1 ] Shanghai Jiao Tong Univ, Sch Med, Affiliated Peoples Hosp 1, Dept Anesthesiol, Shanghai 201620, Peoples R China)

出处:INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 2018

关键词:Streptozotocin;diaphragm;extensor digitorum longus;soleus;diabetes

摘要:The study aimed to investigate the changes induced by diabetes in diaphragm (DIA), extensor digitorumlongus (EDL), and soleus (SOL) contractility and ...

作者:Fu, Danyun;Liu, Haitong;Li, Shitong;Chen, Lianhua;Yao, Junyan

出处:FRONTIERS IN NEUROSCIENCE 2017

摘要:Background: In our previous study, we found that regional administration of delta-opioid peptide [D-Ala(2), D-Leu(5)] enkephalin (DADLE) could provide ...

[外文期刊] Evoked electromyography to rocuronium in orbicularis oris and gastrocnemius in facial nerve injury in rabbits

作者:Xing, Yian;Chen, Lianhua;Li, Shitong

出处:JOURNAL OF SURGICAL RESEARCH 2013

摘要:Background: Muscles innervated by the facial nerve show different sensitivities to muscle relaxants than muscles innervated by somatic nerves, especia ...

作者:Xu, Jing;Yao, Zheng;Li, Shaoqing;Chen, Lianhua

出处:CLINICAL AND INVESTIGATIVE MEDICINE 2013

摘要:Background: The most important consideration for administration of anesthesia in upper airway surgery is maintenance of a patient\'s airway for optima ...

作者:王慧娟,张怡,王赟,陈莲华,李士通 (上海交通大学附属第一人民医院麻醉科)

出处:上海医学 2016

关键词:SLIPA喉罩  潮气量  动脉血-呼气末二氧化碳分压差

摘要:目的观察采用SLIPA喉罩通气时,两种潮气量下的动脉血二氧化碳分压(paCO2)与呼气末二氧化碳分压(paCO2)的差值(ps-esCO2),探讨SLIPA喉罩通气时以petCO2预测paCO2的准确性和不同潮气量对准确性的影响。方法选择择期行平卧位下肢手术的患者40例,美国麻醉医师协会(ASA)分 ...

作者:徐典,魏薇,连明,陈莲华,李士通 (上海交通大学附属第一人民医院麻醉科)

出处:上海医学 2019

关键词:正压呼吸;单肺通气;动态顺应性;肺内分流;氧合;靶控通气

摘要:目的评价依据肺动态顺应性(Cdyn)调节呼气末正压(PEEP)减少单肺通气肺内分流,改善氧合的效应。方法选取上海交通大学附属第一人民医院择期行胸外科手术需单肺通气(OLV)的患者30例,随机分为试验组和对照组,每组15例。试验组将4 cmH 2 O(1 cmH 2 O=0.098 kPa)作为初始P ...

作者:黄勇,吴爽,李士通,魏薇,陈莲华 (上海交通大学附属第一人民医院麻醉科;复旦大学附属中山医院麻醉科)

出处:国际麻醉学与复苏杂志 2019

关键词:面肌;骨骼肌;面神经;诱发肌电位;罗库溴铵;烟碱型乙酰胆碱受体

摘要:目的研究面神经支配的肌肉和肢体神经支配的肌肉对罗库溴铵的敏感性是否存在差异,探讨不同肌肉对罗库溴铵的敏感性差异是否与烟碱型乙酰胆碱受体(nicotinic acetylcholine receptor,nAChR)亚基有关,同时探索不同肌肉nAChR的表达差异是否与聚集蛋白(agrin)/低密度脂蛋 ...

作者:赵晓,黄施伟,王兆民,陈莲华,李士通 (上海交通大学附属第一人民医院麻醉科)

出处:上海医学 2014

关键词:机械通气  喉罩  平卧位  截石位  呼吸动力学

摘要:目的比较喉罩通气下平卧位与截石位手术患者的呼吸动力学监测指标,验证不同手术体位对喉罩通气效果的影响。方法选择全身麻醉下行择期手术的患者60例,年龄20~65岁,美国麻醉医师学会(ASA)分级Ⅰ或Ⅱ级。根据手术体位分为平卧位组和截石位组,每组30例。分别于麻醉绣导前(T0)和喉罩置入1min(T1)、 ...