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作者: Jian Zhang,Shu-Yan Tang,Xiao-Bin Zhu,Peng Li,Jian-Qi Lu,Jiang-Shan Cong,Ling-Bo Wang,Feng Zhang,Zheng Li (Obstetrics and Gynecology Hospital,NHC Key Laboratory of Reproduction Regulation(Shanghai Institute of Planned Parenthood Research),School of Life Sciences,Fudan University,Shanghai 200011,China;Department of Andrology,Center for Men\'s Health,Urologic Medical Center,Shanghai General Hospital,Shanghai Jiao Tong University,Shanghai 200000,China;Department of Research Institute,Reproduction Medical Center,The First Hospital of Lanzhou University,Lanzhou 730000,China)

出处: 亚洲男性学杂志(英文版) 2021 第23卷 第3期 P288-293

关键词: idiopathic;hypogonadotropic;hypogonadism;maternal;inheritance;oligogenic;inheritance;whole;exome;sequencing

摘要: Dozens of genes are associated with idiopathic hypogonadotropic hypogonadism(IHH)and an oligogenic etiology has been suggested.However,the associated ...

作者: Lehao Ren,Wanju Zhang,Jing Zhang,Jiaxiang Zhang,Huiying Zhang,Yong Zhu,Xiaoxiao Meng,Zhigang Yi,Ruilan Wang (Department of Emergency and Critical Care Medicine,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine;Department of Critical Care Medicine,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology;Microbiology Laboratory,Shanghai Municipal Centre for Disease Control and Prevention;Department of Pathology,Zhongshan Hospital,Fudan University;Department of Pathogen Diagnosis and Biosafety,Shanghai Public Health Clinical Center,Fudan University)

出处: Virologica Sinica 2021 第36卷 第6期 P1532-1542

摘要: Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their replication. In this study, we ob ...

作者: Yan Tan,Yang Guo,Amanda B Reed-Maldonado,Zheng Li,Guiting Lin,Shu-Jie Xia,Tom F Lue (Knuppe Molecular Urology Laboratory,Department of Urology,School of Medicine,University of California,San Francisco,CA 94143,USA;Department of Andrology,Renmin Hospital,Hubei University of Medicine,Shiyan 442000,China;Hubei Key Laboratory of Embryonic Stem Cell Research,Hubei University of Medicine,Shiyan 442000,China;Department of Andrology,Renmin Hospital,Hubei University of Medicine,Shiyan 442000,China;Knuppe Molecular Urology Laboratory,Department of Urology,School of Medicine,University of California,San Francisco,CA 94143,USA;Department of Urology,Tripler Army Medical Center,Honolulu,HI 96859,USA;Department of Urology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200080,China;Knuppe Molecular Urology Laboratory,Department of Urology,School of Medicine,University of California,San Francisco,CA 94143,USA)

出处: 亚洲男科学杂志(英文版) 2021 第23卷 第6期 P602-610

关键词: cellular;signaling;pathway;low-intensity;pulsed;ultrasound;mechanism;mechanotransduction;stem;cells

摘要: Low-intensity pulsed ultrasound(LIPUS)is a promising therapy that has been increasingly explored in basic research and clinical applications.LIPUS is ...

作者: 顾本宏,胡剑麟,李君,欧珠罗布,刘晓强 (上海交通大学医学院附属同仁医院泌尿外科;上海交通大学附属第一人民医院男性健康评估中心;西藏阜康医院妇产儿童院区生殖医学中心;西藏大学高原医学中心;天津医科大学总医院)

出处: 高原科学研究 2021

关键词: 高原;低氧;精子;DFI;生育力;性激素

摘要: 目的:探讨移居高原汉族、世居高原藏族和平原汉族男性精液参数特征,分析高原低氧环境对男性生精功能的影响。方法:从不育门诊收集非无精子症男性3 872例,其中移居汉族1 126例,世居藏族1 094例,平原汉族1 652例;行精液常规、精子形态学、精子运动轨迹分析,并分别对686 606例男性行精子DN ...

作者: 匡祎,张凡,李刚,杜联芳,史秋生 (上海交通大学附属第一人民医院超声科)

出处: 临床超声医学杂志 2021

关键词: 超声检查;造影剂;肾上腺肿瘤,良恶性;鉴别诊断

摘要: 目的探讨超声造影增强特征对肾上腺肿瘤良恶性的鉴别诊断价值。方法选取经病理证实的肾上腺肿瘤患者50例(良性29例,恶性21例),均行常规超声及超声造影检查,重点观察并记录肿瘤的超声造影增强特征,包括:增强时相、增强顺序、增强模式、增强程度,并比较其差异。绘制受试者工作特征(ROC)曲线,计算超声造影增 ...

作者: 江鑫辉,郑丽,杜联芳,吴蓉,李朝军,胡文洁,李凡 (上海市宝山区中西医结合医院超声科;上海交通大学附属第一人民医院超声科)

出处: 临床超声医学杂志 2021

关键词: 超声检查;造影剂;睾丸肿瘤;肿瘤样病变;鉴别诊断

摘要: 目的分析成人睾丸肿瘤和肿瘤样病变的常规超声和超声造影特征,探讨超声造影对其的鉴别诊断价值。方法回顾性分析经手术病理证实的睾丸肿瘤、肿瘤样病变患者(睾丸肿瘤组26例、肿瘤样病变组14例)的常规超声和超声造影检查资料,比较两种疾病的影像学特征,分析超声造影对其的诊断效能。结果睾丸肿瘤组、肿瘤样病变组的病 ...

作者: 姚晖,袁伟杰 (上海交通大学附属第一人民医院护理部;上海交通大学附属第一人民医院肾内科)

出处: 中国血液净化 2021

摘要: 腹膜透析相关性腹膜炎(peritoneal dialysis associated peritonitis,PDAP)是腹膜透析的主要并发症'(1)'。多杀巴斯德菌[2](pasteurella multocida)为革兰氏阴性杆菌的一种,是常存在于猫狗等家畜和野生动物上呼吸道的正常菌群,人类可通过 ...

作者: 韩明丽1,史秋生2,陈红燕1,朱慧1,杜联芳2,王栋华1 (1 复旦大学附属闵行医院上海市闵行区中心医院超声科; 2 上海交通大学附属第一人民医院超声科)

出处: 临床超声医学杂志 2021

关键词: 超声检查;造影剂;混合瘤;Warthin瘤;涎腺

摘要: 目的总结涎腺混合瘤与Warthin瘤的超声造影特征,分析二者的差异。方法回顾性分析我院经手术病理证实的17个涎腺混合瘤和16个Warthin瘤的超声造影特征。结果混合瘤超声造影表现以同进(76.5%)、向心性(64.7%)、不均匀性(76.5%)、低增强(70.6%)为主,增强后边界多清晰(88.2 ...

作者: Miao Yu,Zhi-xiao Fang,Wei-wei Wang,Ying Zhang,Zhi-lei Bu,Meng Liu,Xin-hua Xiao,Zi-lu Zhang,Xing-ming Zhang,Yang Cao,Ying-ying Wang,Hu Lei,Han-zhang Xu,Yun-zhao Wu,Wei Liu,Ying-li Wu (Shanghai General Hospital;Hongqiao International Institute of Medicine;Department of Hematology;Department of Transfusion Medicine;Department of Hematology)

出处: 中国药理学报(英文版) 2021

关键词: AML;Wu-5;crenolanib;USP10;FLT3-ITD;AMPKα;Compound;C;METFORMIN

摘要: The kinase FLT3 internal tandem duplication(FLT3-ITD)is related to poor clinical outcomes of acute myeloid leukemia(AML).FLT3 inhibitors have provided ...

作者: YAO Yan,LIU Hua Min,FENG Xia,LI Dong,ZHOU Yong,ZHANG Zhi Hui (Department of Cardiology,Beijing Anzhen Hospital,Capital Medical University;Department of Epidemiology,School of Public Health,Southern Medical University;School of Public Health,Shandong First Medical University & Shandong Academy of Medical Sciences;Clinical Research Institute,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine;Department of Cardiology,the Third Xiangya Hospital of Central South University)

出处: 生物医学与环境科学(英文版) 2021

摘要: Pregnancy is always associated with several important physiological changes in women,including sex hormone levels,glycolipid metabolism,and oxidative ...

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