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作者: Zhao, L., Zhu, J., Cheng, Y., Xiong, Z., Tang, Y., Guo, L., Shi, X.Email Author, Zhao, J.Email Author View Correspondence (jump link) (a Department of Nuclear Medicine, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200080, China b State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China c College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620, China d Experiment Center, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200080, China)

出处: ACS Applied Materials and Interfaces 2015 Vol.7 No.35 P19798-19808

关键词: Engineering controlled terms;Acetylation;Dendrimers;Diseases;Image processing;Particle beams;Photons;Propionic acid;Radioisotopes;Radiotherapy;Tomography;Tumors;Engineering uncontrolled terms;Chlorotoxin;Concentration ranges;Cytocompatibility;glioma;Metallopeptidases;Polyamidoamine dendrimers;Radiochemical purity;SPECT imaging;Engineering main heading;Single photon emission computed tomography;EMTREE drug terms;Chlorotoxin;dendrimer;gelatinase A;macrogol derivative;MMP2 protein, human;PAMAM Starburst;radioactive iodine;radiopharmaceutical agent;scorpion venom;EMTREE medical terms;animal;Bagg albino mouse;cell survival;chemistry;confocal microscopy;drug effects;female;glioma;human;metabolism;mortality;mouse;nude mouse;single photon emission computer tomography;survival rate;tumor cell line;MeSH;Animals;Cell Line, Tumor;Cell Survival;Dendrimers;Female;Glioma;Humans;Iodine Radioisotopes;Matrix Metalloproteinase 2;Mice;Mice, Inbred BALB C;Mice, Nude;Microscopy, Confocal;Polyethylene Glycols;Radiopharmaceuticals;Scorpion Venoms;Survival Rate;Tomography, Emission-Computed, Single-Photon

摘要: Chlorotoxin-conjugated multifunctional dendrimers labeled with radionuclide 131 I were synthesized and utilized for targeted single photon emission c ...

作者: Du, Yiheng;Wang, Yongchuan;Zhang, Fei;Wu, Wenbo;Wang, Wei;Li, Hao;Xia, Shujie;Liu, Haitao (Affiliations 1 Department of Urology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Rd, Shanghai, 200080, China. 2 Department of Urology, Weifang Hospital of Chinese Traditional Medicine, Weifang, 261041, China. 3 Department of Urology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Rd, Shanghai, 200080, China. liuhaitao4@163.com.)

出处: TUMOR BIOLOGY 2015 Vol.36 No.11 P8839-8844

关键词: Bladder cancer (BC); MMP9; WNT signaling; β-Catenin.

摘要: Bladder cancer (BC) is the most popular malignant urinary cancer, with the highest incidence and mortality of all genitourinary system tumors worldwid ...

作者: Ding, Honghua;Wang, Chungang (Affiliations 1 Department of Oncology, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. 2 Department of Radiation Oncology, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, 100 Haining Road, Shanghai, 200080, China. wangchungang_12@163.com.)

出处: TUMOR BIOLOGY 2015 Vol.36 No.9 P6759-6764

关键词: Colorectal cancer; Diphtheria toxin fragment A (DTA); Lgr5; Tumorigenesis.

摘要: The molecular regulation of the growth of colorectal cancer (CRC) cells is not completely understood. Here, we report expression of Lgr5, a stem cell ...

作者: Ding, X.;Zheng, X.;Xing, A.;Wang, D.;Qi, S.;Wu, Y.;Li, H.;Wu, S.;Hong, J. (From the Department of Endocrinology and Metabolism, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China. Department of Cardiology, Kailuan General Hospital, Hebei Union University, Tangshan, China, From the Department of Endocrinology and Metabolism, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China. Department of Cardiology, Kailuan General Hospital, Hebei Union University, Tangshan, China. Department of Cardiology, Bethune International Peace Hospital, Shijiazhuang, China and. Department of Internal Medicine, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China jhong.pku@163.com.)

出处: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE 2015 Vol.108 No.11 P885-890

关键词: Atrial Fibrillation;Diabetes Mellitus;Logistic regression;Predictive Factors

摘要: Background: The pathophysiological mechanisms for atrial fibrillation (AF) vulnerability in diabetic patients are largely unclear. Aim: To investigate ...

作者: Song, Weifeng;Wang, Lei;Wang, Liwei;Li, Qi (Affiliation 1 Department of Medical Oncology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai, 200080, China.)

出处: TUMOR BIOLOGY 2015 Vol.36 No.6 P4741-4745

关键词: Pancreatic ductal adenocarcinoma;FoxO1;miR-21

摘要: Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant primary tumors in humans, with extremely high lethality. Although great efforts h ...

作者: Lu, Qianyi;Lu, Li;Chen, Wei;Chen, Haibing;Xu, Xun;Zheng, Zhi (Affiliation 1 Department of Ophthalmology, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiaotong University, No.100 Haining Road, Shanghai, 200080, China.)

出处: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 2015 Vol.253 No.5 P669-680

关键词: Diabetic retinopathy (DR);Mammalian Diaphanous homolog 1 (mDia-1);Microvascular endothelial dysfunction (MVED);Profilin-1;RhoA

摘要: Diabetic retinopathy (DR) is a major cause of blindness in the working-age populations of developed countries, and effective treatments and prevention ...

作者: Wang, HR (Wang, Huiru)1,2;Yu, B (Yu, Bo)3;Chen, WH (Chen, Wenhua)3;Lu, YZ (Lu, Yingzhi)4;Yu, DH (Yu, Dinghai)2 (Affiliations 1 Department of Physical Education, Shanghai Jiaotong University, 1954 Huashan Road, Shanghai 200030, China ; School of Chinese Martial Arts, Shanghai University of Sports, 399 Changhai Road, Shanghai 200438, China. 2 Department of Rehabilitation, Shanghai First People\'s Hospital, Shanghai Jiaotong University, 100 Haining Road, Shanghai 200080, China. 3 School of Kinesiology, Shanghai University of Sports, 399 Changhai Road, Shanghai 200438, China. 4 School of Chinese Martial Arts, Shanghai University of Sports, 399 Changhai Road, Shanghai 200438, China.)

出处: Evidence-Based Complementary and Alternative Medicine 2015 Vol.2015 P379451

关键词: CONTROLLED-TRIAL;MINERAL DENSITY;EXERCISE;HEALTH;OSTEOPOROSIS;STRENGTH;RISK

摘要: Background. This study examined whether simplified Tai Chi resistance training is superior to traditional Tai Chi in slowing bone loss in postmenopaus ...

作者: Huang, Chen;Shen, Jia-Cheng;Zhang, Jing;Jiang, Tao;Wu, Wei-Dong;Cao, Jun;Huang, Ke-Jian;Qiu, Zheng-Jun (Department of General Surgery, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, 100 Haining Road, Shanghai, 200080, China; Department of General Surgery, Yancheng Third People\'s Hospital, Affiliated Yancheng Hospital, Southeast University Medical College, Yancheng, Jiangsu Province, 224001, China)

出处: WORLD JOURNAL OF GASTROENTEROLOGY 2015 Vol.21 No.48 P13532-13541

摘要: AIM: to assess the diverse immediate and long-term clinical outcomes, a retrospective comparison between laparoscopic and conventional operation was p ...

作者: Shi, Changgui;Yang, Chengwei;Gao, Rui;Yuan, Wen (Department of Spine Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China; Department of Spine Surgery, Lanzhou General Hospital of PLA, Lanzhou, China; Department of Orthopaedics, Shanghai First People\'s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China)

出处: WORLD NEUROSURGERY 2015 Vol.84 No.5 P1466-1472

摘要: OBJECTIVE: Postoperative delirium can occur following various types of surgeries. The specific risk factors for delirium following spinal surgery have ...

作者: Zhang, Qi-Sheng;Han, Bing;Xu, Jian-Hua (Affiliation 1 Qi-Sheng Zhang, Bing Han, Jian-Hua Xu, Peng Gao, Yu-Cui Shen, Digestive Endoscopy Center, Department of Gastroenterology and Hepatology, Branch of Shanghai First People\'s Hospital, Jiaotong University, Shanghai 200081, China.)

出处: WORLD JOURNAL OF GASTROENTEROLOGY 2015 Vol.21 No.15 P4715-4721

关键词: Adverse events; Antibiotic prophylaxis; Cefuroxime; Endoscopic mucosal resection; Endoscopic submucosal dissection.

摘要: Abstract Aim: To investigate the effect of prophylaxis with antibiotics on clinical adverse events in patients who underwent endoscopic submucosa ...

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