作者： Wang, Wei ;Liu, Zhihong ;Qu, Ping ;Zhou, Zhengdong ;Zeng, Yigang ;Fan, Jie ;Liu, Yong ;Guo, Yifeng ;Qiu, Jianxin （1 1 Department of Urology, Shanghai First People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China 2 2 Department of Urology, The Fourth Affiliated Hospital of Nantong University (Yancheng First People’s Hospital), Jiangsu, China）

出处： PLoS ONE 2013 Vol.8 No.5 P1-10

关键词： Biochemistry;Biology;Bladder cancer;Bladder cancer and urothelial neoplasias of the urinary tract;Cancer genetics;Cancers and neoplasms;Enzyme classes;Enzymes;Genetics;Genitourinary tract tumors;Ligases;Medicine;Metabolism;Oncology;Protein metabolism;Research Article;Surgery;Surgical oncology;Urology

摘要： Regulator of Cullins-1 (ROC1) is a key subunit in the Cullin-RING ligase (CRL) protein complex. Overexpression of ROC1 protein is associated with tumo ...

作者： Zeng, Hui ;Sun, Mengxiong ;Zhou, Chenghao ;Yin, Fei ;Wang, Zhuoying ;Hua, Yingqi ;Cai, Zhengdong （1 1 Department of Orthopedics, Shanghai First People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 2 Department of Orthopedics, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China 3 3 The Advanced Institute of Translational Medicine, Tongji University, Shanghai, China）

出处： PLoS ONE 2013 Vol.8 No.10 P1-11

关键词： Research Article

摘要： We investigated the antitumor effect and mechanism of hematoporphyrin monomethyl ether-mediated photodynamic therapy (HMME-PDT) in sarcomas. Intracell ...

作者： Xiao-yong Shen;Zhi-feng Lin;Qiang Lin( xklinqiang@hotmail.com);Zhen Ruan;Hai-long Huang;Chao-qiang Ju;Jin Wang （1 Department of Thoracic Surgery, Huadong Hospital, Shanghai Fudan University, Shanghai, China 2 Department of Thoracic Surgery, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai, China）

出处： Contemporary Oncology / Wspolczesna Onkologia 2013 Vol.17 No.2 P210-213

关键词： carcinoma;diagnosis;lung neoplasms;treatment

摘要： Sarcomatoid carcinoma (SC) is a rare primary-malignant tumor in which both carcinomatous and sarcomatous elements occur. It can occur in many differen ...

作者： Dong, S.H.;Chen, H.N.;Tian, J.W.;Xia, T.;Wang, L.;Zhao, Q.H.;Liu, C.Y. （a Department of Orthopaedics, Shanghai First People Hospital affiliated to Shanghai Jiaotong University, No. 100 Haining Road, 200080 Shanghai, China; b Department of Orthopaedics, Second Affiliated Hospital of Soochow University, No.1055 Sanxiang Road, 215004 Suzhou, China）

出处： Orthopaedics and Traumatology: Surgery and Research 2013 Vol.99 No.4 P405-411

关键词： Minimally invasive surgery Trans-muscular spatium approach;Pedicle screws;Spinal fractures

摘要： Objective: To compare the outcomes of minimally invasive percutaneous short-segment pedicle instrumentation (SSPI) with that of trans-spatium intermus ...

作者： Yang, Tingting ;Qiu, Haifeng ;Bao, Wei ;Li, Bilan ;Lu, Cong ;Du, Guiqiang ;Luo, Xin ;Wang, Lihua ;Wan, Xiaoping （1 1 Department of Obstetrics and Gynecology, Shanghai First People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 2 Department of Obstetrics and Gynecology, International Peace Maternity & Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China 3 3 Department of the Center of Research Laboratory, International Peace Maternity & Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： PLoS ONE 2013 Vol.8 No.6 P1-12

关键词： Basic cancer research;Biology;Cancer detection and diagnosis;Cancer treatment;Cancers and neoplasms;Endometrial carcinoma;Epigenetic therapy;Epigenetics;Gene expression;Gene function;Genetics;Gynecologic cancers;Gynecological tumors;Medicine;Metastasis;Obstetrics and gynecology;Oncology;Research Article;Tumor physiology

摘要： Objective: EFEMP1, the epidermal growth factor–containing fibulin-like extracellular matrix protein 1, functions as an oncogene or a tumor suppressor ...

作者： Li, Bi-Qing ;Huang, Tao ;Zhang, Jian ;Zhang, Ning ;Huang, Guo-Hua ;Liu, Lei ;Cai, Yu-Dong （1 2 Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, P. R. China 2 3 Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York City, New York, United States of America 3 4 Department of Ophthalmology, Shanghai First People\'s Hospital Affiliated to Shanghai Jiaotong University, Shanghai, P. R. China 4 5 Department of Biomedical Engineering, Tianjin University, Tianjin Key Lab of BME Measurement, Tianjin, P. R. China 5 1 Institute of Systems Biology, Shanghai University, Shanghai, P. R. China）

出处： PLoS ONE 2013 Vol.8 No.5 P1-8

关键词： Algorithms;Applied mathematics;Autosomal dominant;Biology;Clinical genetics;Clinical research design;Computational biology;Computer science;Genetics;Hereditary nonpolyposis colorectal cancer;Human genetics;Mathematics;Medicine;Research Article;Statistical methods;Statistics;Systems biology

摘要： Colorectal cancer can be grouped into Dukes A, B, C, and D stages based on its developments. Generally speaking, more advanced patients have poorer pr ...

作者： Zhao, Qing‐hua;Wang, Shou‐guo;Liu, Shao‐xian;Li, Ji‐peng;Zhang, Yong‐xing;Sun, Zhong‐yi;Fan, Qi‐ming;Tian, Ji‐wei （1 Department of Orthopaedics, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiaotong University, China 2 Department of Orthopaedics, Huai\'an First People\'s Hospital, Nanjing Medical University, Huai\'an China 3 Department of Orthopaedic Surgery, YanTaiShan Hospital, Yantai ShanDong China 4 Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People\'s Hospital, Shanghai JiaoTong University School of Medicine, China）

出处： FEBS Journal 2013 Vol.280 No.22 P5801-5814

关键词： adipogenesis;C/ EBPα;C/EBP;epigenetics;osteogenesis;PPAR;PPARγ

摘要： The balance between osteogenesis and adipogenesis of bone marrow stromal cells is impaired in many human diseases. Knowledge of how to fine-tune this ...

作者： Meng XX;Wang RL;Gao S;Xie H;Tan JT;Qian YB （Affiliation 1 Department of Critical Care Medicine, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 201620, China.）

出处： World Journal Of Emergency Medicine 2013 Vol.4 No.2 P133-137

关键词： A549 cell;Oxidative stress;Paraquat;Ulinastatin

摘要： Background: Ulinastatin (UTI) is a urinary trypsin inhibitor extracted and purified from urine of males. This study aimed to explore the effects of UT ...

作者： Ma, YH (Ma, Yuhang)¹;Yang, C (Yang, Cheng)²;Tao, YM (Tao, Yimin)^2,3;Zhou, H (Zhou, Hu)^2,3;Wang, YF (Wang, Yufan)¹ （1 Department of Endocrinology and Metabolism, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai China 2 Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China 3 CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai China）

出处： FEBS Journal 2013 Vol.280 No.22 P5668-5681

关键词： clinical application;diabetic nephropathy;diabetic retinopathy;proteomics;translational research

摘要： Diabetic microangiopathy has become a heavy social burden worldwide, but at present it is still difficult to predict and diagnose this ailment at an e ...

作者： Li-jie Gu;Yu-ran Zhang;Wei-jie Yuan;Ling Wang;Zheng Zhang;Lei Chen;Jing Wang;Sheng Chen （Department of Nephrology, Shanghai First People\'s Hospital Affiliated Shanghai Jiaotong University, Shanghai 200080, China.）

出处： Zhonghua nei ke za zhi 2013 Vol.52 No.6 P453-458

摘要： OBJECTIVE: To evaluate intradialytic blood pressure variability (BPV) in patients on maintenance hemodialysis (MHD), and to investigate the correlated ...