作者： Di Pan  ¹, Pan Li  ², Xiaoling Dai  ³, Shiyun Xie  ² （Affiliations ¹ Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. hp031031@163.com. ² Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. ³ Shanghai Putuo Traditional Chinese Medicine Hospital, Shanghai, China.）

出处： Reproductive sciences (Thousand Oaks, Calif.) 2024

关键词： 25-hydroxyvitamin D;Causal relationship;Endometriosis;Endometriosis of ovary;Mendelian randomization.

摘要： Numerous studies have demonstrated a correlation between serum 25-hydroxyvitamin D (25OHD) and endometriosis. However, the precise nature of this asso ...

作者： Binqiang Xu  ¹, Yang Fu  ², Nuoming Yin  ², Wenfei Qin  ³, Zehua Huang  ², Wei Xiao  ³, Huizhen Huang  ⁴, Qixiang Mei  ², Junjie Fan  ⁵, Yue Zeng  ⁵, Chunlan Huang  ⁵ （Affiliations ¹ Department of Gastroenterology, Shanghai Key Laboratory of Pancreatic Diseases, Shanghai JiaoTong University School of Medicine, Shanghai, China. ² Shanghai Key Laboratory of Pancreatic Disease, Shanghai Key Laboratory of Pancreatic Disease, Shanghai JiaoTong University School of Medicine, Shanghai, China. ³ Department of Gastroenterology, University of Shanghai for Science and Technology, Shanghai, China. ⁴ Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai, China. ⁵ Department of Gastroenterology, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.）

出处： American journal of physiology. Gastrointestinal and liver physiology 2024

关键词： Bacteroides thetaiotaomicron;Faecalibacterium prausnitzii;fecal microbiota transplantation;gut microbiota;inflammatory bowel disease.

摘要： Fecal microbiota transplantation (FMT) is a promising therapy for inflammatory bowel disease (IBD) via rectifying gut microbiota. The aim of this stud ...

作者： Enjun He ^{#  1}, Haitao Sui ^{#  2}, Hongjie Wang ^{#  1}, Xiang Zhao  ³, Weihong Guo  ¹, Zhicheng Dai  ¹, Zhenkai Wu  ⁴, Kai Huang  ⁵, Qinghua Zhao  ⁶ （Affiliations ¹ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ² Department of Orthopaedics, Dongying People's Hospital, Dongying, Shandong, China. ³ Department of Surgery of Spine and Spinal Cord, People's Hospital of Henan University, Henan Provincial People's Hospital, Henan, Zhengzhou, China. ⁴ Department of Pediatric Orthopaedics, Shanghai Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁵ Department of Orthopedics, Zhabei Central Hospital of Jing'an District, Shanghai, China. 13817784210@163.com. ⁶ Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. qinghua.zhao@shgh.cn.）

出处： Stem cell reviews and reports 2024

关键词： Aging;BMSCs;IL-19;Osteoporosis;sFRP1.

摘要： Background: Cellular senescence is an important process related to the pathogenic mechanism of different disorders, especially bone loss. During senes ...

作者： Zeyu Wang  ¹, Xue Wang  ², Xinyue Dai  ¹, Tianming Xu  ³, Xiaoqin Qian  ⁴, Meiqi Chang  ⁵, Yu Chen  ^{1   6} （Affiliations ¹ Materdicine Lab, School of Life Sciences, Shanghai University, Shanghai, 200444, P. R. China. ² Department of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, P. R. China. ³ Department of Orthopedics, 905th Hospital of PLA Navy, Naval Medical University, Shanghai, 200050, P. R. China. ⁴ Department of Ultrasound Medicine, Northen Jiangsu People's Hospital, Yangzhou, Jiangsu, 225009, P. R. China. ⁵ Laboratory Center, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, P. R. China. ⁶ Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Institute of Shanghai University, Wenzhou, Zhejiang, 325088, P. R. China.）

出处： Advanced materials (Deerfield Beach, Fla.) 2024

关键词： apoptosis;calcium overload;catalytic biomaterials;ferroptosis;nanozyme;ultrasound.

摘要： The introduction of glucose oxidase, exhibiting characteristics of glucose consumption and H₂ O₂ production, represents an emerg ...

作者： De-Wei An  ^{1   2   3}, Yu-Ling Yu  ^{2   3}, Azusa Hara  ⁴, Dries S Martens  ⁵, Wen-Yi Yang  ⁶, Yi-Bang Cheng  ¹, Qi-Fang Huang  ¹, Kei Asayama  ^{2   7}, Katarzyna Stolarz-Skrzypek  ⁸, Marek Rajzer  ⁸, Peter Verhamme  ⁹, Tim S Nawrot  ^{3   5}, Yan Li  ¹, Jan A Staessen  ^{1   2   10} （Affiliations ¹ Department of Cardiovascular Medicine, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. ² Non-Profit Research Association Alliance for the Promotion of Preventive Medicine. ³ Research Unit Environment and Health, KU Leuven Department of Public Health and Primary Care, University of Leuven, Leuven, Belgium. ⁴ Division of Drug Development and Regulatory Science, Faculty of Pharmacy, Keio University, Japan. ⁵ Center for Environmental Sciences, Hasselt University, Hasselt, Belgium. ⁶ Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ⁷ Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan. ⁸ First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University, Kraków, Poland. ⁹ Center for Molecular and Vascular Biology, KU Leuven Department of Cardiovascular Sciences. ¹⁰ Biomedical Sciences Group, Faculty of Medicine, University of Leuven, Leuven, Belgium.）

出处： Journal of hypertension 2024

摘要： Objectives: We undertook time-stratified analyses of the National Health and Nutrition Examination Survey in the US to assess time trends (1999-2020) ...

作者： Yan Hu  ¹, Xiaoqun Li  ², Xiao Chen  ¹, Sicheng Wang  ³, Liehu Cao  ⁴, Hao Zhang  ¹, Yunfei Zhang  ⁵, Zhiwei Wang  ⁶, Baoqing Yu  ⁷, Peijian Tong  ⁸, Qiang Zhou  ⁹, Feng Niu  ¹⁰, Weiguo Yang  ¹¹, Wencai Zhang  ¹², Shijie Chen  ¹³, Qiang Yang  ¹⁴, Tao Shen  ¹⁵, Peng Zhang  ¹⁶, Yong Zhang  ⁵, Jun Miao  ¹⁴, Haodong Lin  ¹⁷, Jinwu Wang  ¹⁸, Lei Wang  ¹⁹, Xin Ma  ²⁰, Hongjian Liu  ²¹, Ilia Stambler  ^{22   23}, Long Bai  ²⁴, Han Liu  ²⁴, Yingying Jing  ²⁴, Guohui Liu  ²⁵, Xinglong Wang  ²⁶, Dongliang Wang  ¹, Zhongmin Shi  ²⁰, Robert Chunhua Zhao  ^{23   27}, Jiacan Su  ^{1   24} （Affiliations ¹ Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. ² First Affiliated Hospital of Naval Medical University, Shanghai, China. ³ Shanghai Zhongye Hospital, Shanghai, China. ⁴ Luodian Hospital, Baoshan District, Shanghai, China. ⁵ Tangdu Hospital Air Force Medical University, Xi'an, China. ⁶ Eastern Hepatobiliary Surgery Hospital, Shanghai, China. ⁷ Shanghai Pudong New Area People's Hospital, Shanghai, China. ⁸ Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou, China. ⁹ Third Affiliated Hospital of Chongqing Medical University, Chongqing, China. ¹⁰ First Bethune Hospital of Jilin University, Changchun, China. ¹¹ HKU Li Ka Shing Faculty of Medicine, Hongkong, China. ¹² First Affiliated Hospital of Jinan University, Guangzhou, China. ¹³ Third Xiangya Hospital of Central South University, Changsha, China. ¹⁴ Tianjin Hospital, Tianjin, China. ¹⁵ Shengjing Hospital of Chinese Medical University, Shenyang, China. ¹⁶ Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China. ¹⁷ Shanghai General Hospital, Shanghai, China. ¹⁸ Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ¹⁹ Ruijin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, China. ²⁰ Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China. ²¹ First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. ²² Department of Science, Technology and Society, Bar Ilan University, Ramat Gan, Israel. ²³ International Society on Aging and Disease, Bryan, TX, USA. ²⁴ Institute of Translational Medicine, Shanghai University, Shanghai, China. ²⁵ Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ²⁶ Department of Pharmacology & Toxicology, University of Arizona, Tucson, USA. ²⁷ Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.）

出处： Aging and disease 2024

摘要： Osteoporotic fractures are the most severe complications of osteoporosis, characterized by poor bone quality, difficult realignment and fixation, slow ...

作者： Yun Zhang  ¹, Ge Tian  ¹, Xueni Sun  ¹, Xiaoli Yang  ¹, Yi Zhang  ¹, Wenqing Tan  ¹, Liangwei Duan  ², Shunxiang Gao  ³, Junping Yu  ^{4   5} （Affiliations ¹ Laboratory of Infection and Immunology, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, People's Republic of China. ² Laboratory of Infection and Immunology, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, People's Republic of China. duanliangwei@xxmu.edu.cn. ³ Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People's Republic of China. shunxianggao@163.com. ⁴ Laboratory of Infection and Immunology, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, People's Republic of China. yujp@wh.iov.cn. ⁵ CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, People's Republic of China. yujp@wh.iov.cn.）

出处： Mikrochimica acta 2024

关键词： S. aureus;Chicken IgY;Specificity;Wheat germ agglutinin.

摘要： A novel colorimetric platform was designed for the determination of S. aureus by utilizing a dual-recognition strategy, where wheat germ agglutinin (W ...

作者： Jie Mei  ^{1   2}, Yun Cai  ³, Rui Xu  ^{1   2}, Qing Li  ⁴, Jiahui Chu  ^{1   2}, Zhiwen Luo  ⁵, Yaying Sun  ⁶, Yuxin Shi  ⁷, Junying Xu  ⁷, Di Li  ⁸, Shuai Liang  ⁷, Ying Jiang  ⁹, Jiayu Liu  ⁹, Zhiwen Qian  ³, Jiaofeng Zhou  ¹⁰, Mengyun Wan  ¹⁰, Yunlong Yang  ¹¹, Yichao Zhu  ¹⁰, Yan Zhang  ^{3   9}, Yongmei Yin  ^{1   12} （Affiliations ¹ Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, P. R. China. ² The First Clinical Medicine College, Nanjing Medical University, Nanjing, Jiangsu, P. R. China. ³ Departments of Gynecology, Wuxi Maternal and Child Health Care Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, P. R. China. ⁴ Departments of Oncology, Xuzhou Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, P. R. China. ⁵ Department of Sports Medicine, Huashan Hospital Affiliated to Fudan University, Shanghai, P. R. China. ⁶ Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China. ⁷ Departments of Oncology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, P. R. China. ⁸ Shanghai Outdo Biotech Co., Ltd., National Engineering Center for Biochip, Shanghai, P. R. China. ⁹ Departments of Gynecology, Wuxi Maternity and Child Health Care Hospital, Affiliated Women's Hospital of Jiangnan University, Wuxi, Jiangsu, P. R. China. ¹⁰ Department of Physiology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, P. R. China. ¹¹ Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, P. R. China. ¹² Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Personalized Cancer Medicine, Nanjing Medical University, Nanjing, Jiangsu, P. R. China.）

出处： Cancer communications (London, England) 2024

关键词： collagen deposition;immune infiltration;immunotherapy;pan‐cancer;tumor microenvironment.

摘要： Background: Immune checkpoint blockade (ICB) has revolutionized the treatment of various cancer types. Despite significant preclinical advancements in ...

作者： 陆方林 （上海市第一人民医院心血管外科）

出处： 中国心血管病研究 2024

关键词： 三尖瓣关闭不全；经导管三尖瓣置换；经导管三尖瓣修复；三尖瓣关闭不全综合征

摘要： 三尖瓣关闭不全（tricuspid regurgitation,TR）是最常见的心脏瓣膜疾病之一，患者基数庞大。疾病的隐匿性使得TR患者长期未受到重视，但随着严重TR患者表现出累及全身多脏器的临床症状、较差的生活质量以及较低的生存率，TR逐步受到关注。当前对重度TR的药物治疗效果不佳，且患者常常由于 ...

作者： 周致远^1,2，陈家浩³，宋泓辰¹，杨博宇¹ （¹首都医科大学附属北京友谊医院泌尿外科；²上海市浦东新区公利医院神经外科；³上海交通大学附属第一人民医院泌尿外科）

出处： 中华肿瘤防治杂志 2024

关键词： 前列腺癌；纳米硒；氧化应激；硒化镉；前列腺特异性抗原

摘要： 目的 对含硒纳米材料在前列腺癌诊疗中的研究进展进行综述分析，为其临床应用提供参考思路。方法 以“硒、纳米硒、前列腺癌”为关键词，检索PubMed和CNKI期刊全文数据库1970-01-01-2023-12-31发表的相关文献。纳入标准：（1）有硒或含硒纳米材料参与的临床研究；（2）包括前列腺癌化疗、 ...