作者：Chen, Binbin ;Zhang, Yi ;Chen, Lianhua ;Huang, Shiwei ;Li, Shitong ;Yao, Junyan （1 Department of Anesthesiology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处：PLoS ONE 2013

关键词：Anesthesiology;Animal models;Animal models of disease;Animal types;Biology;Clinical research design;Medicine;Model organisms;Neurology;Neuropharmacology;Neurosurgical care;Research Article;Small animals;Spinal cord diseases;Spinal cord injury;Veterinary science

摘要：Background: The β2 adrenergic receptor (β2AR) plays an important role in ischemia-reperfusion (I/R) injury in various organs. Recently, a selective β2 ...

作者：Yu, Fujun;Chen, Bicheng;Dong, Peihong;Zheng, Jianjian （a Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China; b Department of Gastroenterology, Songjiang Hospital Affiliated Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, 201600, China; c Department of Gastroenterology, Shanghai Songjiang Hospital Affiliated to Nanjing Medical University, Nanjing, 210029, China; d Key Laboratory of Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China）

出处：MOLECULAR THERAPY 2017

关键词：DNA methylation;DNA methyltransferase;DNMT;homeobox transcript antisense RNA;HOTAIR;microRNA-29b;phosphatase and tensin homolog deleted on chromosome 10;PTEN

摘要：Homeobox transcript antisense RNA (HOTAIR), as a long intergenic non-coding RNA (lincRNA), is upregulated in various cancers and involved in diverse c ...

作者：Cheng QJ;Huang SG;Chen YZ;Lin JT;Zhou X;Chen BY;Feng YL;Ling X;Sears MR （Department of Pulmonary Disease, Ruijin Hospital, Shanghai Jiao Tong University, No.150 Wu Yi Road, Shanghai, 200025, China. chengqijian@aliyun.com.;Department of Pulmonary Disease, Ruijin Hospital, Shanghai Jiao Tong University, No.150 Wu Yi Road, Shanghai, 200025, China. huangshaoguang@vip.163.com.;Capital Institute of Pediatrics, Beijing, China. chenyuzhi@gmail.com.;Department of Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China. jiangtao_l@263.net.;Department of Respiratory Medicine, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China. xzhou53@163.com.;Department of Respiratory Disease, Tianjin Medical University General Hospital, Tianjin, China. cbynew@126.com.;Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China. fengyulin1115@126.com.;Medical and Regulatory Affairs, AstraZeneca China, Shanghai, 201203, China. Xia.Ling@astrazeneca.com.;Michael G DeGroote School of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada. searsm@mcmaster.ca.）

出处：BMC Pulm Med 2016

摘要：BACKGROUND: As- needed formoterol can effectively relieve asthma symptoms. Since budesonide/ formoterol is available as maintenance and reliever thera ...

作者：Yuchen Bai;Xiaoxia Chen;Likun Hou;Jun Qian;Tao Jiang;Caicun Zhou;Maciej Ciebiada （1 Department of General and Oncological Pulmonology, University Clinical Hospital Norbert Barlicki, Medical University of Lodz, Lodz 50243, Poland, 2 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China, 3 Department of Medical Oncology, 4 Department of Pathology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China, 5 Department of Medical Oncology, Suzhou Cancer Center, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215000, China,）

出处：Cancer Biol Med 2018

关键词：Non-small cell lung cancer;EGFR mutation;PD-L1;CD8;survival

摘要：Objective: Epidermal growth factor receptor (EGFR) activation was reported to upregulate programmed death-ligand 1 (PD-L1) expression in lung cancer c ...

作者：Zhang C;Chen B;Guo A;Zhu Y;Miller JD;Gao S;Yuan C;Kutschke W;Zimmerman K;Weiss RM;Wehrens XH;Hong J;Johnson FL;Santana LF;Anderson ME;Song LS （Division of Cardiovascular Medicine, Department of Internal Medicine (C.Z., B.C., A.G., Y.Z., S.G., W.K., R.M.W., F.L.J., M.E.A., L.-S.S.) and Department of Molecular Physiology and Biophysics (M.E.A.), University of Iowa Carver College of Medicine, Iowa City, IA; Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai, China (Y.Z., J.H.); Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN (J.D.M.); Department of Pharmacology, College of Basic Medicine, Anhui Medical University, Hefei, China (S.G.); Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, WA (C.Y., L.F.S.); Department of Veterans Affairs Medical Center, Iowa City, IA (K.Z.); and Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX (X.H.T.W.).;）

出处：Circulation 2014

摘要：BACKGROUND: Cardiac dysfunction in failing hearts of human patients and animal models is associated with both microtubule densification and transverse ...

作者：Gu, Yu-Qian¹;Yang, Zi-Li¹;Cao, Rong²;Zhong, Ke¹;Chen, Bin³ （1 College of Environmental Science and Engineering, Donghua University, Shanghai; 201620, China (2 Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai; 201620, China (3 Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing; 100029, China）

出处：Zhongguo Huanjing Kexue/China Environmental Science 2020

摘要：To prevent the excessive growth of molds and bacteria in the air-conditioning system (ACs), the inhibiting effects on common molds and bacteria in ACs ...

作者：Zhong, Xiaoming;Chen, Bin;Yang, Zhiwen （Department of Pharmacy, Songjiang Hospital Affiliated Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China; Jiangxi Province Tumor Hospital, Nanchang, China; Surgery Department, First Affiliated Hospital of Gannan Medical University, Gannan Medical University, Ganzhou, China）

出处：Cellular Physiology and Biochemistry 2018

摘要：In the original article by Zhong et al., entitled "The Role of Tumor-Associated Macrophages in Colorectal Carcinoma Progression" [Cell Physiol Biochem ...

作者：Zhang, CM (Zhang, Caimei)¹;Chen, BY (Chen, Biyi)¹;Wang, YH (Wang, Yihui)^1,2;Guo, A (Guo, Ang)¹;Tang, YQ (Tang, Yiqun)^1,3;Khataei, T (Khataei, Tahsin)¹;Shi, Y (Shi, Yun)¹;Kutschke, WJ (Kutschke, William J.)¹;Zimmerman, K (Zimmerman, Kathy)⁴;Weiss, RM (Weiss, Robert M.)¹ （a Division of Cardiovascular Medicine, Department of Internal Medicine, Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, United States; b Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai, China; c Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, China; d Department of Veterans Affairs Medical Center, Iowa City, IA, United States; e Department of Pathophysiology, School of Medicine, Shenzhen University, Shenzhen, China; f Department of Surgery, Ohio State University Medical Center, Columbus, OH, United States）

出处：Journal of Molecular and Cellular Cardiology 2017

关键词：Calcium;Cardiomyocytes;Excitation-contraction coupling;MG53 (or TRIM72);Sodium-calcium exchanger;T-tubules

摘要：The cardiac transverse (T)-tubule membrane system is the safeguard for cardiac function and undergoes dramatic remodeling in response to cardiac stres ...

作者：Wang, Yihui, MS;Chen, Biyi, MD;Huang, Chun-Kai, MS;Guo, Ang, PhD;Wu, Jennifer, BS;Zhang, Xiaoming, MD, PhD;Chen, Rong, MS;Chen, Cheng, MS;Kutschke, William, MS;Weiss, Robert M., MD;Boudreau, Ryan L., PhD;Margulies, Kenneth B., MD;Hong, Jiang, MD, PhD;Song, Long-Sheng, MD （Affiliations 1 Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China. 2 Division of Cardiovascular Medicine, Department of Internal Medicine & François M. Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine; Iowa City, Iowa. 3 Department of Veterans Affairs Medical Center, Iowa City, Iowa. 4 Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.）

出处：JACC: Basic to Translational Science 2018

关键词：CAPN1-OE, calpain-1 overexpressing; E-C coupling, excitation-contraction coupling; EF, ejection fraction; IP, intraperitoneally; ISO, isoproterenol; JP2, junctophilin-2; JP2-OE, junctophilin-2 overexpressing; LV, left ventricle/ventricular; MI, myocardial infarction; RV, right ventricular; SR, sarcoplasmic reticulum; T-tubule, transverse tubule; T-tubules; TAB, transverse aortic banding; TTpower, strength of regularity of the T-tubule system; WT, wild-type; calcium; calpain; excitation-contraction coupling; heart failure.

摘要：Heart failure remains a major cause of morbidity and mortality in developed countries. There is still a strong need to devise new mechanism-based trea ...

作者：陈蓓熙 （上海市第一人民医院宝山分院急诊科）

出处：特别健康(下半月) 2014

关键词：急诊  优质护理  体会

摘要：目的 ：探讨急诊开展优质护理服务的方法及效果。方法：转变观念，强化服务意识及技能；优化就诊流程；加强护理风险管理，完善急诊病人的转运交接；简化护理文件书写；完善护理绩效分配。结果：开展优质护理后，病人满意度从 85.8%提高至94.5%，提高了护理质量。结论：急诊开展优质护理服务，提高了病人满意度， ...