作者： Yanrui Jin¹;Zhiyuan Li¹;Chengjin Qin¹CA1;Jinlei Liu¹;Yunqing Liu¹;Liqun Zhao²;Chengliang Liu¹CA2 （¹State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China;²Department of Cardiology, Shanghai First People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200080, China）

出处： Biomedical Signal Processing and Control 2023

关键词： Attention mechanism;Convolution neural network;ECG quality assessment;Long short-term memory neural network

摘要： ECG quality assessment is of great significance to reduce false alarms in automatic arrhythmia and other cardiovascular diseases diagnoses and reduce ...

作者： lei tang，guo-tong xu，jing-fa zhang （Department of Ophthalmology of Tongji Hospital Tongji Eye Institute Department of Regenerative Medicine and Department of Pharmacology Tongji University School of Medicine Shanghai China Department of Ophthalmology of Tongji Hospital Tongji Eye Institute Department of Regenerative Medicine and Department of Pharmacology Tongji University School of Medicine Shanghai China；Department of Ophthalmology Shanghai General Hospital (Shanghai First People’s Hospital) Shanghai Jiao Tong University Shanghai China Department of Ophthalmology Shanghai General Hospital (Shanghai First People’s Hospital) Shanghai Jiao Tong University Shanghai China；National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus Diseases Shanghai Engineering Center for Visual Science and Photomedicine Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases Shanghai China National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus Diseases Shanghai Engineering Center for Visual Science and Photomedicine Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases Shanghai China）

出处： Neural Regeneration Research 2023

关键词： anti-inflammation；therapy；anti-vascular；endothelial；growth；factor；diabetic；retinopathy；hyperreflectivity；foci；inflammation；inflammatory；cells；inflammatory；cytokines；leukostasis；microglia；Müller；cells

摘要： Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients ...

作者： Lei Tang  ¹, Guo-Tong Xu  ¹, Jing-Fa Zhang  ² （Affiliations ¹ Department of Ophthalmology of Tongji Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China. ² Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University; National Clinical Research Center for Eye Diseases; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai Engineering Center for Visual Science and Photomedicine; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.）

出处： Neural regeneration research 2023

关键词： Müller cells;anti-inflammation therapy;anti-vascular endothelial growth factor;diabetic retinopathy;hyperreflectivity foci;inflammation;inflammatory cells;inflammatory cytokines;leukostasis;microglia.

摘要： Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients ...

作者： 唐智，郎蕾，王任远，顾松 （东华大学机械工程学院；上海市第一人民医院创伤临床医学中心）

出处： 中国组织工程研究 2023

关键词： 拇外翻；有限元模型；生物力学分析；第1跖趾关节角；第1跖骨

摘要： 背景：有限元模型构建及生物力学分析使探究拇外翻足的形成及相关结构功能恢复成为可能。目的：建立负重中立位中度拇外翻足有限元模型，分析不同部位及大小的外力作用下第1跖趾关节角度的变化与对应骨骼应力分布情况。方法：选取1名女性中度拇外翻志愿者，采集CT影像数据，利用计算机三维成像技术进行三维有限元建模，验 ...

作者： Chao Zhong^1,2;Yueming Wu^1,2;Haodong Lin^3,4CA1;Runhui Liu^1,5,6CA2 （¹State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China;²C. Z. and Y. W. have equally contributed to the manuscript.;³Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;⁴Jiading Branch of Shanghai General Hospital, Shanghai, 201803, China;⁵Frontiers Science Center for Materiobiology and Dynamic Chemistry, Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism, Research Center for Biomedical Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China;⁶East China University of Science and Technology Shenzhen Research Institute, Shenzhen 518063, China）

出处： Composites Part B: Engineering 2023

摘要： Osteomyelitis is a major complication of orthopedic diseases with high recurrence and morbidity, along with long hospital stays and high medical costs ...

作者： Dan-Dan Liu¹，Chao-Yang Zhang^2,3，Jing-Ting Zhang^2,3，Li-Min Gu⁴，Guo-Tong Xu¹，Jing-Fa Zhang^2,3 （¹Department of Ophthalmology of Tongji Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine；²Department of Ophthalmology, Shanghai General HospitalShanghai First People's Hospital, Shanghai Jiao Tong University；³National Clinical Research Center for Eye Diseases,Shanghai Key Laboratory of Ocular Fundus Diseases,Shanghai Engineering Center for Visual Science and Photomedicine,Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases；⁴Department of Ophthalmology, Shanghai Aier Eye Hospital）

出处： Neural Regeneration Research 2023

关键词： diabetic；retinopathy；DNA；methylation；epigenetics；histone；modification；metabolic；memory；M⁶A；modification；non-coding；RNAs；review

摘要： Epigenetics focuses on DNA methylation, histone modification, chromatin remodeling, noncoding RNAs, and other gene regulation mechanisms beyond the DN ...

作者： Chong Chen  ¹, Guangyi Hu, Feng'e Chen, Kun Liu, Suqin Yu, Xun Xu （Affiliation ¹ Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.）

出处： Retina (Philadelphia, Pa.) 2023

摘要： Carbon fiber microelectrodes and carbon fiber composite minielectrodes (CFM/CFCM) have been generally used for measurements of nitric oxide (NO) conce ...

作者： 何明，胡艳艳，刘金涛，王丽慧，张国兵 （嘉兴市中医医院；上海市第一人民医院）

出处： 中国中医药科技 2023

关键词： 参芪救心散；急性ST段抬高型心肌梗死；PCI；心肌损伤；心功能

摘要： 目的：探讨参芪救心散对于经皮冠状动脉介入治疗(PCI)的急性ST段抬高型心肌梗死(STEMI)患者在疗效、心肌损伤及心功能方面的影响。方法：选取2020年1月—2020年12月本院收治的STEMI患者50例，随机数字表法分为观察组和对照组，每组25例。两组患者PCI前均给予西药负荷剂量，术后均给予西 ...

作者： 丁忠冰，王勇丽，李孝洁，鞠嫄，陈丽，万勤，黄昭鸣 （华东师范大学教育学部康复科学系；华东师范大学中国言语听觉康复科学与ICF应用研究院；上海市第一人民医院康复医学科；华东师范大学附属卢湾辅读实验学校）

出处： 听力学及言语疾病杂志 2023

关键词： 痉挛型脑瘫；实时言语重读训练法；言语流利性障碍；疗效

摘要： 目的 探讨实时言语重读训练治疗痉挛型脑瘫儿童言语流利性障碍的临床疗效。方法 选取2020年10月至2021年3月就诊且符合入选标准的44例5～7岁痉挛型脑瘫儿童为研究对象，按随机数表法分为观察组与对照组，每组22例。对照组进行常规言语康复训练，观察组在此基础上进行实时言语重读训练，每组患者共训练10 ...

作者： 杨涵，郭巧梅，王薛庆，舒文 （上海交通大学附属第一人民医院检验医学中心）

出处： 中国感染控制杂志 2023

关键词： 宏基因组；感染性疾病；性能评估；mNGS

摘要： 目的 对三家宏基因组测序(mNGS)平台开展性能评估。方法 三家平台(A、B和C)对18个参考品和8个临床标本进行mNGS，分析检测灵敏度、特异度、阴性预测值和阳性预测值。结果 A、B和C平台对于参考品的灵敏度分别为97.8%、100%、45.1%，特异度分别为50.0%、100%、100%，阴性预 ...