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作者: Xiaorui Cao  1, Linli Xue  1, Xiuju Yu  1, Yi Yan  1, Jiayin Lu  1, Xiaomao Luo  1, Haidong Wang  1, Juan Wang  1   2 (Affiliations 1 College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi 030801, China. 2 Department of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China.)

出处: Aging 2024

关键词: exosomes;miR-140-5p;muscle injury repair;muscle satellite cells;regeneration.

摘要: Muscle satellite cells (SCs) play a crucial role in the regeneration and repair of skeletal muscle injuries. Previous studies have shown that myogenic ...

作者: Shengyong Diao  1, Ziting Yin  1, Xinjian Chen  1   2, Menghan Li  3, Weifang Zhu  1, Muhammad Mateen  1, Xun Xu  3, Fei Shi  1, Ying Fan  3 (Affiliations 1 MIPAV Lab, the School of Electronics and Information Engineering, Soochow University, Suzhou, China. 2 The State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China. 3 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: Medical physics 2024

关键词: adversarial learning;deep learning;retinal OCT image segmentation;unsupervised domain adaptation.

摘要: Background: Deep learning based optical coherence tomography (OCT) segmentation methods have achieved excellent results, allowing quantitative analysi ...

作者: Lijuan Huang1,2;Xueqing Bai2;Yan Xie2;Yunyu Zhou2;Jin Wu2;Ningdong Li1,2,3CA11Department of Ophthalmology, The Second Affiliated Hospital of Fujian Medical University, 362000, Quanzhou, China;2Department of Ophthalmology, Beijing Children’s Hospital, Capital Medical University, 100045, Beijing, China;3Department of Ophthalmology, Shanghai General Hospital, 200940, Shanghai, China)

出处: Orphanet Journal of Rare Diseases 2024

关键词: Congenital stationary night blindness;Myopia;Strabismus;Mutation

摘要: Background Congenital stationary night blindness (CSNB) is an inherited retinal disorder. Most of patients have myopia. This study aims to describe t ...

作者: Hang Zhao  1, Wenhua Li  2, Xin Zhou  3, Liang Pan  3, Yun Feng  4, Pingyu Gao  5, Jie Ji  6, Huanyan Zhang  6, Kai Zhao  3, Chi Wang  7, Zhanjun Lu  3   4 (Affiliations 1 Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, China. 2 Department of Gastroenterology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 3 Department of Gastroenterology, Jintan Hospital, Jiangsu University, Changzhou, China. 4 Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. 5 Pathology Center, Jintan Hospital, Jiangsu University, Zhenjiang, China. 6 Clinical Laboratory, Jintan Hospital, Jiangsu University, Zhenjiang, China. 7 Department of Precision Mechanical Engineering, Shanghai University, Shanghai, China.)

出处: Journal of innate immunity 2024

关键词: CXCL1;Colitis;Gut microbiota;Inflammation;Neutrophil.

摘要: Introduction: C-X-C motif chemokine ligand 1 (CXCL1) is a potent neutrophil chemoattractant that plays a pivotal role in recruiting neutrophils during ...

作者: Tianjiao Guo  1   2   3, Kun Liu  4   5   6, Haidong Zou  4   5   6, Xun Xu  4   5   6, Jie Yang  2, Qi Yu  4   5   6 (Affiliations 1 Institute of Medical Robotics, Shanghai Jiao Tong University, China. 2 Department of Automation, Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, China. 3 School of Biomedical Engineering, Shanghai Jiao Tong University, China. 4 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. 5 National Clinical Research Center for Eye Diseases, Shanghai, China. 6 Shanghai Clinical Research Center for Eye Diseases, China.)

出处: Digital health 2024

关键词: Color fundus photography;deep learning;image quality assessment;pre-diagnosis;screening.

摘要: Purpose: Color fundus photography is widely used in clinical and screening settings for eye diseases. Poor image quality greatly affects the reliabili ...

作者: Hongwei Shi  1, Xiaojing Hao  1, Yaqin Sun  1, Yating Zhao  1, Yue Wang  1, Xiaorui Cao  1, Zeen Gong  1, Shusen Ji  1, Jiayin Lu  1, Yi Yan  1, Xiuju Yu  1, Xiaomao Luo  1, Juan Wang  2, Haidong Wang  1 (Affiliations 1 College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, P.R. China. 2 Department of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P.R. China.)

出处: Acta physiologica (Oxford, England) 2024

关键词: AMPK;browning;exercise;extracellular vesicle;integrin αV;irisin.

摘要: Aim: Exercise can reduce body weight and promote white fat browning, but the underlying mechanisms remain largely unknown. This study investigated the ...

作者: Yanzheng Chen  1, Xueliang Zhang  1, Qing Wang  2, Chang Du  3   4, Chang-Ming Dong  1 (Affiliations 1 School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China. cmdong@sjtu.edu.cn. 2 Department of Stomatology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, P. R. China. 3 Clinical Cancer Institute, Center for Translational Medicine, Naval Military Medical University, Shanghai, 200433, P. R. China. cdu@shsci.org. 4 State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200240, P. R. China.)

出处: Biomaterials science 2024

摘要: Regulating the wound microenvironment to promote proliferation, vascularization, and wound healing is challenging for hemostats and wound dressings. H ...

作者: Shengzhou Li  1, Yiming Chen  2, Xiangqian Cao  1, Chenkai Yang  1, Wei Li  3, Bing Shen  1   4 (Affiliations 1 Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China. 2 Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China. 3 Department of Nanomedicine & Shanghai Key Lab of Cell Engineering, Naval Medical University, 200433, Shanghai, China. 4 Shanghai Tenth People's Hospital of Tongji University, 200072, Shanghai, China.)

出处: Nanomedicine (London, England) 2024

关键词: graft function evaluation;immunosuppressants;kidney transplantation;nanotechnology;organ preservation.

摘要: Kidney transplantation is a crucial treatment option for end-stage renal disease patients, but challenges related to graft function, rejection and imm ...

作者: S Y Zhao  1, H M Liu  2, Q Lu  3, X C Liu  1, J G Hong  4, E M Liu  5, Y X Zou  6, M Yang  7, Z M Chen  8, H L Zhang  9, D Y Zhao  10, X B Zhang  11, Y Yin  12, X Y Dong  3, X X Lu  13, J R Liu  1, L N Chen  2 (Affiliations 1 Department of No.2 Respiratory Medicine, Beijing Children's Hospital, Capital Medical University, National Clinical Research Center for Respiratory Diseases, National Center for Children's Health, Beijing 100045, China. 2 Department of Pediatric Pulmonology and Immunology, West China Second University Hospital, Sichuan University, Chengdu 610041, China. 3 Department of Pulmonology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China. 4 Department of Pediatrics, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200080, China. 5 Department of Respiratory, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. 6 Department of Pulmonology, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Machang Compus, Tianjin 300074, China. 7 Department of Pharmacy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China. 8 Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China. 9 Department of Pediatric Respiratory Medicine, the Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, China. 10 Department of Respiratory Medicine, Children's Hospital of Nanjing Medical University, Nanjing 210008, China. 11 Department of Respiratory Disease, Children's Hospital of Fudan University, Shanghai 201102, China. 12 Department of Respiratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China. 13 Department of Respiratory Medicine, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430015, China.)

出处: Zhonghua er ke za zhi = Chinese journal of pediatrics 2024

摘要: 2023年肺炎支原体肺炎(MPP)在全国流行,国家卫生健康委员会于2023年2月发布“儿童肺炎支原体肺炎诊治指南”,但在实施过程中仍需要根据目前MPP特点,对重要诊治环节更加具体地指导和建议,现对MPP早期诊断方法、重症MPP判断依据和预警指标、各类抗支原体药物适应证、大环内酯类药物无反应性处理原则 ...

作者: Shangbi Chen  1   2, Dewen Liu  1   2, Weiwei Chen  3, Huajiang Chen  1, Jiawei Li  2, Jinfang Wang  2 (Affiliations 1 Shanghai Xin Yue Lian Hui Electronic Technology Co. Ltd, Shanghai, P.R. China. 2 Inertial Technology Division, Shanghai Aerospace Control Technology Institute, Shanghai, P.R. China. 3 Department of Nursing, Shanghai General Hospital, Shanghai Jiao Tong University School of Nursing, Shanghai, P.R. China.)

出处: Beilstein journal of nanotechnology 2024

关键词: crack sensors;helical structure;polydimethylsiloxane (PDMS);ultrahigh sensitivity;ultrahigh stretchability.

摘要: The majority of crack sensors do not offer simultaneously both a significant stretchability and an ultrahigh sensitivity. In this study, we present a ...

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