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作者: Jian,Zhang ;Meihua,Zhang ;Huijie,Zhao ;Xun,Xu (Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai 200080, China; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200080, China; National Clinical Research Center for Eye Diseases, Shanghai 20080, China; Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai 20080, China. \'(1)\' ; Maternal and Child Health Care Hospital of Shandong Province, Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Jinan 250002, PR China. [2] ; NCI-Frederick National Laboratory, Laboratory of Cellular and Development Signaling, Frederick, MD 21702, USA. Electronic address: huijie.zhao@nih.gov. [3] ; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai 200080, China; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200080, China; National Clinical Research Center for Eye Diseases, Shanghai 20080, China; Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai 20080, China. Electronic address: drxuxun@tom.com. [4])

出处: Biochimica et biophysica acta. Molecular basis of disease P165794

关键词: Disease gene;Laplacian heat diffusion;Proliferative diabetic retinopathy

摘要: Diabetic retinopathy is a common complication of diabetes mellitus that causes pathogenic damage to the retina. Particularly, the proliferative diabet ...

作者: Ting-Ting,Wu ;Te,Liu ;Xuan,Li ;Ya-Jing,Chen ;Tian-Jiao,Chen ;Xiao-Ying,Zhu ;Jiu-Lin,Chen ;Qing,Li ;Ye,Liu ;Ya,Feng ;Yun-Cheng,Wu (Department of Neurology \'(1)\' ; Shanghai General Hospital [2] ; Shanghai Jiao Tong University School of Medicine [3] ; Shanghai 200080 [4] ; P.R. China. [5] ; Shanghai Geriatric Institute of Chinese Medicine [6] ; Longhua Hospital [7] ; Shanghai University of Traditional Chinese Medicine [8] ; Shanghai [9] ; 200031 [10] ; P.R.China. [11] ; The State Key Laboratory of Medical Neurobiology [12] ; The Institutes of Brain Science and the Collaborative Innovation Center for Brain Science [13] ; Shanghai Medical College [14] ; Fudan University [15] ; 200032 [16])

出处: Human molecular genetics

摘要: It has been reported that abnormal epigenetic modification is associated with the occurrence of Parkinson\'s disease (PD). Here, we found that a Ten-E ...

作者: Fei,Lyu ;Hui-Xiang,Wang ;Chun,Bi ;Shu-Ming,Shen ;Qiu-Gen,Wang ;Xiao-Ming,Wu (Department of Orthopaedics, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China. \'(1)\' ; Department of Orthopaedic Traumatology, Trauma Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [2])

出处: Orthopaedic surgery

关键词: Case series;Functional outcome;Humeral shaft fracture;Shoulder dislocation;Surgery

摘要: To gain a better understanding of the traumatic mechanism and to develop appropriate treatment for dislocation of the shoulder joint with an ipsilater ...

作者: Zixiang,Geng ;Bimeng,Zhang (Department of Acupuncture-Moxibustion, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China. \'(1)\')

出处: Acupuncture in medicine : journal of the British Medical Acupuncture Society

作者: Depeng,Meng ;Yichen,Meng ;Bingyang,Li ;Guigang,Zeng ;Bin,Zhang ;Chunlin,Hou ;Haodong,Lin ;Yueping,Ouyang (Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, PR China. \'(1)\' ; Department of Rehabilitation, Changzheng Hospital, Second Military Medical University, Shanghai, PR China. [2] ; Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, PR China; Department of Orthopedics, Integrated Chinese and Western Medicine Hospital of Minhang District, Shanghai, PR China. [3] ; Department of Orthopedics Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, PR China. Electronic address: linhaodong1978@smmu.edu.cn. [4] ; Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, PR China. Electronic address: Oyaopin@aliyun.com. [5])

出处: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association

摘要: Comminuted patellar fractures are not rare, and the ideal treatment method remains controversial. The present study was conducted to evaluate effects ...

作者: Xianyu Fan;Ji Li;Shengyuan Wu;Jingjing Jiang;Jiajing Wang;Shuowen Wang;Yuefen Lou;Guorong Fan (Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P. R. China;Fan and Li contributed equally to this work.;Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P. R. China;School of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, P. R. China;Fan and Li contributed equally to this work.;Laboratory of Drug Metabolism &Pharmacokinetics, School of Medicine, Tongji University, Shanghai, P. R. China;Department of Pharmacy, Shanghai Fourth People\'s Hospital Affiliated to Tongji University School of Medicine, Shanghai, P. R. China;Shanghai Center for Drug Evaluation and Inspection, Shanghai, P. R. China;Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P. R. China;Department of Pharmacy, Shanghai Fourth People\'s Hospital Affiliated to Tongji University School of Medicine, Shanghai, P. R. China;Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P. R. China;Laboratory of Drug Metabolism &Pharmacokinetics, School of Medicine, Tongji University, Shanghai, P. R. China;Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, P. R. China;Prof. Guorong Fan, Department of Clinical Pharmacy, Shanghai General Hospital, No. 100 Haining Road, Shanghai 200080, P.R. China.)

出处: Journal of Separation Science

关键词: 9‐hydroxyrisperidone;capillary zone electrophoresis;field‐amplified sample injection;pharmacokinetics;risperidone

摘要: This article describes a method for the simultaneous quantitation of risperidone and its major metabolite, 9‐hydroxyrisperidone, in beagle dog plasma ...

作者: Zhong Zheng;Zhixian Yao MD;Ke Wu MD;Junhua Zheng MD (Department of Evidence‐based Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;Shanghai Medical Aid Team in Wuhan, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;Department of Evidence‐based Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;Shanghai Medical Aid Team in Wuhan, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;Department of Evidence‐based Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;Shanghai Medical Aid Team in Wuhan, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;Department of Evidence‐based Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;Shanghai Medical Aid Team in Wuhan, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China)

出处: Journal of Medical Virology

关键词: chest radiography;computed tomography;coronavirus disease 2019;coronavirus pneumonia;diagnosis;polymerase chain reaction

摘要: The rapid emergence of coronavirus disease 2019 (COVID‐19) has necessitated the implementation of diverse pandemic control strategies throughout the w ...

作者: Dong li Li;Lei Mao;Qing Gu;Fang Wei;Yuan-yuan Gong (Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 20080 ; National Clinical Research Center for Eye Diseases, Shanghai, China, 200080 ; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China, 200080 ; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China, 200080 ; Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China, 200080 Department of Ophthalmology, Huadong hospital Affiliated to Fudan University, 221 West YanAn Road, Shanghai, PR China, 200040 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 20080 ; National Clinical Research Center for Eye Diseases, Shanghai, China, 200080 ; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China, 200080 ; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China, 200080 ; Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China, 200080 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 20080 ; National Clinical Research Center for Eye Diseases, Shanghai, China, 200080 ; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China, 200080 ; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China, 200080 ; Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China, 200080 Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 20080 ; National Clinical Research Center for Eye Diseases, Shanghai, China, 200080 ; Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China, 200080 ; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China, 200080 ; Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China, 200080)

出处: Cutaneous and Ocular Toxicology

关键词: Autophagy status;Outer blood-retina barrier;Tight junction;Human retinal pigment epithelial cells;Quercetin

摘要: Age-related macular degeneration (AMD) is the primary cause of irreversible severe visual loss among the elderly globally. Oxidative stress acts as a ...

作者: Min Li;Yunjie Yu;Ying Yuan;Peng Wang;Xiaojun Hu;Chengcheng Zhu;Bilian Ke (Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University , Shanghai, China ;Department of Ophthalmology, Zhongshan Hospital affiliated with Fudan University , Shanghai, China. Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University , Shanghai, China ; Shanghai Key Laboratory of Fundus Disease , Shanghai, China; Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University , Shanghai, China ; Shanghai engineering center for visual science and photomedicine , Shanghai, China; Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University , Shanghai, China ; Shanghai engineering center for precise diagnosis and treatment of eye diseases , Shanghai, China; Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University , Shanghai, China ; National Clinical Research Center for Eye Diseases; Shanghai , China; Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University , Shanghai, China ; Shanghai Key Laboratory of Fundus Disease , Shanghai, China; Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University , Shanghai, China ; National Clinical Research Center for Eye Diseases; Shanghai , China;)

出处: Current Eye Research

关键词: Rete ridges;inflammatory cytokines;meibomian gland dysfunction;dry eye

摘要: Purpose To evaluate the morphology and function of rete ridges in eyelid margin and inflammatory cytokines in meibomian gland dysfunction (MGD) assoc ...

[外文期刊] Rationale and study design for ablation of paroxysmal atrial fibrillation guided by ablation index: a multi-center, prospective randomized trial (PAF-AI trial).
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作者: Ruhong,Jiang ;Minglong,Chen ;Jie,Fan ;Fu,Yi ;Anli,Tang ;Xingpeng,Liu ;Wenqing,Zhu ;Shaowen,Liu ;Xiaobo,Huang ;Weizhu,Ju ;Xi,Zhang ;Jie,Li ;Jiangui,He ;Liang,Shi ;Genqing,Zhou ;Yuegang,Wang ;Chenyang,Jiang (Department of Cardiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Road, Zhejiang, 310016, Hangzhou, People\'s Republic of China. \'(1)\' ; The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. [2] ; The First Peoples\' Hospital of Yunnan Province, Yunnan, China. [3] ; Xijing Hospital, Air Force Medical University, Xi\'an, China. [4] ; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. [5] ; Beijing Chaoyang Hospital affiliated to Capital Medical University, Beijing, China. [6] ; Zhongshan Hospital, Fudan University, Shanghai, China. [7] ; Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. [8] ; Nanfang Hospital, Southern Medical University, Guangzhou, China. [9] ; Department of Cardiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Road, Zhejiang, 310016, Hangzhou, People\'s Republic of China. cyjiang@zju.edu.cn. [10])

出处: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

关键词: Ablation index;Atrial fibrillation;Catheter ablation;Contact force;Radiofrequency ablation

摘要: Pulmonary vein isolation (PVI) has become the cornerstone of atrial fibrillation (AF) ablation, but long-term success rates remains suboptimal, due in ...

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