作者： Yong Huang;Yian Xing;Hong Wang;Lianhua Chen;Shitong Li （¹Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Scientific Reports 2017

摘要： Previous research has indicated that differences in sensitivities to muscle relaxants exist between facial nerve- and somatic nerve-innervated muscles ...

作者： Junjie Hang;Peng Xue;Haiyan Yang;Shaobo Li;Donghui Chen;Lifei Zhu;Weiyi Huang;Shujuan Ren;Yue Zhu;Liwei Wang （¹Department of Medical Oncology and Pancreatic Cancer Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, New Songjiang Road 650, Shanghai, 201620, China;²Shanghai Key laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai, 201620, China;³Department of Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Pujian Road 160, Shanghai, 200120, China;⁴Pathology Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Road 100, Shanghai, 200080, China）

出处： Scientific Reports 2017

摘要： Although previous studies demonstrated that elevated C-reactive protein to albumin ratio (CAR) predicted poor prognosis in various solid tumors, littl ...

作者： Hai Hu;Ting Han;Meng Zhuo;Lei-lei Wu;Cuncun Yuan;Lixia Wu;Wang Lei;Feng Jiao;Li-Wei Wang （¹Department of Medical Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 650 New Songjiang Road, Shanghai, 201620, China;²Shanghai Key Laboratory of Pancreatic Disease, Shanghai, 201620, China;³School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 201620, China;⁴Department of Pathology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620, P.R. China）

出处： Scientific Reports 2017

摘要： Cyclooxygenase-2 (COX-2) was stated to be overexpression in various human malignancies associating with angiogenesis, metastasis and chemoresistence. ...

作者： Ting Wang;Qiujing Yu;Jingjie Li;Bin Hu;Qin Zhao;Chunmin Ma;Wenhua Huang;Lingang Zhuo;Houqin Fang;Lujian Liao;Y. Eugene Chin;Yuhui Jiang （¹The Institute of Cell Metabolism, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, 200080, China;²Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200080, China;³Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, China;⁴Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, 320 Yueyang Road, 200031, China）

出处： Nature Cell Biology 2017

摘要： Chromatin-associated fumarase (FH) affects histone methylation via its metabolic activity. However, whether this effect is involved in gene transcript ...

作者： Chao Liu;Hyowon Choi;Zariel I. Johnson;Jiwei Tian;Irving M. Shapiro;Makarand V. Risbud （¹Department of Orthopaedic Surgery and Graduate Program in Cell and Developmental Biology, Thomas Jefferson University, Philadelphia, PA, USA;²Department of Orthopaedics, The Central Hospital of Songjiang District, Shanghai, China;³Department of Orthopaedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China）

出处： Scientific Reports 2017

摘要： Nucleus pulposus (NP) cells reside in a physiologically hyperosmotic environment within the intervertebral disc. TonEBP/NFAT5 is an osmo-sensitive tra ...

作者： Zhiye Wu;Guoqin Chen;Jianwu Zhang;Yongquan Hua;Jinliang Li;Bei Liu;Anqing Huang;Hekai Li;Minsheng Chen;Caiwen Ou （¹Department of Cardiology, Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China;²Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China;³Cardiovascular Medicine Department of Central Hospital of Panyu District, Guangzhou, 510280, China;⁴Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China;⁵Department of Cardiology, Shanghai general hospital, Shanghai, 200000, China）

出处： Scientific Reports 2017

摘要： The effect of transplanted rat mesenchymal stem cells (MSCs) can be reduced by extracellular microenvironment in myocardial infarction (MI). We tested ...

作者： Zelin Cui;Xiaokui Guo;Ke Dong;Yan Zhang;Qingtian Li;Yongzhang Zhu;Lingbing Zeng;Rong Tang;Li Li （¹Department of Laboratory Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;²Department of Immunology and Microbiology, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China;³Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China）

出处： Scientific Reports 2017

摘要： Staphylococcus phages of the Myoviridae family have a wide host range and potential applications in phage therapy. In this report, safety assessments ...

作者： Maimaiti Yisireyili;Motoharu Hayashi;Hongxian Wu;Yasuhiro Uchida;Koji Yamamoto;Ryosuke Kikuchi;Mohammad Shoaib Hamrah;Takayuki Nakayama;Xian Wu Cheng;Tadashi Matsushita;Shigeo Nakamura;Toshimitsu Niwa;Toyoaki Murohara;Kyosuke Takeshita （¹Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan;²Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;³Department of Blood Transfusion, Nagoya University Hospital, Nagoya, Japan;⁴Department of Clinical Laboratory, Nagoya University Hospital, Nagoya, Japan;⁵Department of Blood Transfusion, Aichi Medical University Hospital, Nagakute, Japan;⁶Department of Pathology, Nagoya University Hospital, Nagoya, Japan;⁷Faculty of Health and Nutrition, Shubun University, Ichinomiya, Aichi, Japan）

出处： Scientific Reports 2017

摘要： Chronic stress is closely linked to the metabolic syndrome, diabetes, hyperuricemia and thromboembolism, but the mechanisms remain elusive. We reporte ...

作者： Shuyu Xiong;Xiangui He;Junjie Deng;Minzhi Lv;Jiali Jin;Sifei Sun;Chunxia Yao;Jianfeng Zhu;Haidong Zou;Xun Xu （¹Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, 200040, China;²Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200080, China;³School of Public Health, Fudan University, Shanghai, 200032, China;⁴Jiading Center for Disease Prevention and Control, Shanghai, 201901, China;⁵Songjiang Center for Disease Prevention and Control, Shanghai, 201620, China）

出处： Scientific Reports 2017

摘要： The purpose of the cross-sectional study is to describe the values and distribution of choroidal thickness and to explore its related factors, especia ...

作者： Tao Chen;Jingjie Li;Meidong Xu;Qin Zhao;Yingyong Hou;Liqing Yao;Yunshi Zhong;Ping-Chieh Chou;Wei Zhang;Pinghong Zhou;Yuhui Jiang （¹Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China;²The Institute of Cell Metabolism, Shanghai Key Laboratory of Pancreatic disease, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 201620, China;³Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China;⁴Department of Cancer Biology, Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Winston-Salem, NC, 27157, USA）

出处： Nature Communications 2017

摘要： EGFR signaling is implicated in NF-κB activation. However, the concrete mechanisms by which the core transducer of NF-κB signaling pathway, RelA/p65 i ...