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作者: Zhongquan Zhou;Songwen Chen;Zhiming Tian;Shibing Deng;Xuying Yi;Shaning Yang;Xuexin Yang;Lijun Jin;Wanqing Shi (Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, Shanghai General Hospital, Shanghai 200000, China Department of Cardiology, First School of Clinical Medicine College, Yangtze University, Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China The First Hospital of Jingzhou City, The Interventional Center, Jingzhou 434000, China)

出处: Acta Biochimica et Biophysica Sinica

关键词: hypoxia-inducible factor-1;cardiomyocytes;hypoxia;miR-20b-5p;NF-κB

摘要: Chronic hypoxia is a common inducer of end-stage cardiovascular disease. In cells under hypoxia, the hypoxia-inducible factor-1 (HIF-1) plays a vital ...

作者: Yingying Zhang;Xingjing Li;Mudan He;Guoqing Zhang;Wuping Bao;Xia Fei;Xue Zhang;Min Zhang;Pengyu Zhang (a Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China b Department of Respiratory Medicine, The Shanghai First People’s Hospital of Baoshan Branch, Shanghai, China)

出处: Biomedicine & Pharmacotherapy Vol.133 P111018

作者: Federico Corvi;Li Su;Srinivas R. Sadda (1 Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA 2 Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA 3 Eye Clinic, Department of Biomedical and Clinical Science “Luigi Sacco”, Sacco Hospital, University of Milan, Milan, Italy 4 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of medicine, Shanghai, China)

出处: Eye Vol.35 No.1 P110-120

摘要: The advent of optical coherence tomography angiography (OCTA) has allowed a qualitative and quantitative analysis of the retinal vasculature and the c ...

作者: Federico Corvi;Li Su;Srinivas R. Sadda (1 Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA 2 Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA 3 Eye Clinic, Department of Biomedical and Clinical Science “Luigi Sacco”, Sacco Hospital, University of Milan, Milan, Italy 4 Department of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of medicine, Shanghai, China)

出处: Eye Vol.35 No.1 P110-120

摘要: The advent of optical coherence tomography angiography (OCTA) has allowed a qualitative and quantitative analysis of the retinal vasculature and the c ...

作者: Zi Wang;Yunke Bi (National Key Laboratory of Science and Technology on Micro/Nano Fabrication, Shanghai Jiao Tong University, Shanghai, 200240 China;Department of Neurosurgery, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 201620 China)

出处: Electroanalysis

关键词: hydrogen peroxide;electrochemical sensor;porous silicon;metal-assisted chemical etching;hierarchical structure

摘要: Three‐dimensional porous silicon framework (3D‐pSi) integrated with various nanostructures is highly potential for functional devices usage such as mi ...

作者: Jianhua Ma;Bin Zhang;Jianing Hou;Yongde Peng (Department of Endocrinology, Nanjing First Hospital, Nanjing, China Lilly China Drug Development and Medical Affairs Center, Shanghai, China Department of Endocrinology and Metabolism, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, China)

出处: Diabetes Therapy

关键词: Dulaglutide;East Asian patients;Type 2 diabetes

摘要: Introduction This subgroup analysis assessed the efficacy and safety of once weekly dulaglutide 1.5 mg and 0.75 mg in East Asian patients with type 2 ...

作者: Fan Yu;Zhong-Sen Le;Li-Hua Chen;Hong Qian;Bo Yu and Wen-Hua Chen (Department of Rehabilitation, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. * Fan Yu and Zhong-sen Le should be regarded as co-first authors. Search for more papers by this author ; Department of Neurosurgery, Fuyang Hospital of Anhui Medical University, Fuyang, China. * Fan Yu and Zhong-sen Le should be regarded as co-first authors. Search for more papers by this author ; Department of Rehabilitation, Shanghai Fifth Rehabilitation Hospital, Shanghai, China. Search for more papers by this author ; Department of Rehabilitation, Shanghai Fifth Rehabilitation Hospital, Shanghai, China. Search for more papers by this author ; Address correspondence to: Dr. Bo Yu, Department of Rehabilitation, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100, Haining Road, Shanghai 200080, China E-mail Address: bobby_jtu@163.com Department of Rehabilitation, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. Search for more papers by this author ;and Dr. Wen-hua Chen, Department of Rehabilitation, Shanghai General Hospital, Shanghai Jiao Tong University, No. 100, Haining Road, Shanghai 200080, China E-mail Address: chen.wh@163.com Department of Rehabilitation, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. Search for more papers by this author)

出处: Journal of Computational Biology Vol.0 No.0

关键词: Gene Ontology;miRNA-target;Parkinson\'s disease;pathway;protein–protein interaction;rotenone

摘要: To explore the expression changes of genes and the pathological processes-related genetic information in Parkinson\'s disease (PD) model induced by ro ...

作者: Kaichun Wang;Chao Gu;Daode Hu (Department of Clinical Pharmacology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;Department of Clinical Pharmacology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;Department of Clinical Pharmacology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;Daode Hu, Department of Clinical Pharmacology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.)

出处: British Journal of Clinical Pharmacology

关键词: anticancer drugs;chemotherapy;drug safety;pharmacovigilance

摘要: TS‐1, an effective anticancer drug that consists of tegafur, gimeracil and oteracil, has been increasingly used for the treatment of many types of can ...

作者: Yumeng Cao;Xia Chen;Yuqi Liu;Xingyi Zhang;Yun Zou;Jinbao Li (Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China)

出处: Inflammation Research

关键词: PIM1;Acute lung injury;Pulmonary microvascular endothelial cells;ELK3;ICAM1

摘要: Objective The dysfunction of pulmonary microvascular endothelial cells (PMVECs) is one of the critical characteristics of acute lung injury/acute res ...

作者: Dao-Nan Chen;Jiang Du;Yun Xie;Ming Li;Rui-Lan Wang;Rui Tian (Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China)

出处: International Urology and Nephrology

关键词: AKI;Potassium;Sodium

摘要: Purpose Acute kidney injury (AKI) is a common organ dysfunction in ICU and up to now there is no good way to predict the AKI progression and patient ...

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