发明人： 史向阳，李丹，范钰，林丽洲，杜联芳

申请号： 201910141429.5

申请日期： 2019.02.26

摘要： 本发明涉及一种基于UTMD的双载药纳米平台及其制备方法和应用，包括：利用一步水热法合成碳点y‑CDs；在氨基末端的树状大分子上连接抗癌药物TPGS得到G5‑TPGS；将G5‑TPGS与y‑CDs通过非共价作用结合形成纳米杂化材料G5‑TPGS@y‑CDs；负载抗癌药物阿霉素DOX得到(G5‑TPGS ...

发明人： 史向阳，徐放，朱建志，张昌昌，孙文杰，杜联芳，林丽洲

申请号： 201910783699.6

申请日期： 2019.08.23

摘要： 本发明涉及一种负载二氧化锰和阿霉素的纳米水凝胶及其制备和应用，包括：聚N‑乙烯基己内酰胺纳米水凝胶负载二氧化锰和药物。本发明制备方法简单，产物易于纯化，成本低廉。制备的纳米水凝胶粒径较小，分布均匀，具有良好的水溶性、胶体稳定性和生物相容性。制备的纳米水凝胶可以作为核磁共振成像造影剂，结合超声靶向微泡 ...

作者： Du, Jing;Sun, Ying;Li, Feng-Hua;Du, Lian-Fang;Duan, You-Rong

出处： JOURNAL OF BIOSCIENCES 2017 Vol.42 No.2 P299-309

摘要： We investigated the efficacy and safety of ultrasound (US)-targeted microbubble (MB) destruction (UTMD)-enhanced delivery of monomethoxypoly(ethylene ...

作者： Li, Fan;Liu, Yang;Cai, Yingyu;Li, Xin;Bai, Min;Sun, Ting;Du, Lianfang

出处： ULTRASOUND IN MEDICINE AND BIOLOGY 2018 Vol.44 No.5 P1044-1052

摘要： This study investigated the impact of ultrasound (US) irradiation on the hepatic differentiation of human bone marrow mesenchymal stem cells (hBMSCs) ...

作者： Lin, Lizhou;Fan, Yu;Gao, Feng;Jin, Lifang;Li, Dan;Sun, Wenjie;Li, Fan;Qin, Peng;Shi, Qiusheng;Shi, Xiangyang;Du, Lianfang

出处： THERANOSTICS 2018 Vol.8 No.7 P1923-1939

摘要： Conventional chemotherapy of pancreatic cancer (PaCa) suffers the problems of low drug permeability and inherent or acquired drug resistance. Developm ...

作者： Xiao, Yunchao;Wang, Mengyuan;Lin, Lizhou;Du, Lianfang;Shen, Mingwu;Shi, Xiangyang

出处： ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2018 Vol.255

作者： Li, Zhao-jun;Du, Lian-fang;Qin, Yan;Liu, Ji-bin;Luo, Xiang-hong

出处： CURRENT MEDICAL SCIENCE 2018 Vol.38 No.4 P727-733

摘要： Renal transplant (RT) recipients have a high risk of developing cardiovascular diseases. However, the effects of renal transplantation on the developm ...

作者： Li, Zhaojun;Qin, Yan;Du, Lianfang;Luo, Xianghong

出处： BMC MEDICAL IMAGING 2018 Vol.18

摘要： Background: Renal transplantation can significantly improve the quality of life of patients with end stage renal disease (ESRD) who would otherwise re ...

作者： Bai, Min;Dong, Yang;Huang, Hui;Fu, Hao;Duan, Yourong;Wang, Qi;Du, Lianfang

出处： RSC ADVANCES 2019 Vol.9 No.10 P5682-5691

摘要： At present, the treatment of triple negative breast cancer (TNBC) is a worldwide problem, urgently requiring early precise diagnosis and effective tre ...

作者： Xiao, Yunchao;Wang, Mengyuan;Lin, Lizhou;Du, Lianfang;Shen, Mingwu;Shi, Xiangyang

出处： NANOMEDICINE 2019 Vol.14 No.2 P183-199

摘要： Aim: To develop a multifunctional nanofibrous mat-embedded microfluidic chip system for specific capture and intact release of circulating tumor cells ...