作者： 倪秀石¹，吴方²，宋娟^3,4，安丽娜¹，蒋倩雯²，白婷婷²，王建业⁵，于普林⁵，张存泰⁶，吴锦晖^3,4，中华医学会老年医学分会 （¹上海交通大学附属第一人民医院老年医学科；²上海交通大学医学院附属瑞金医院老年病科；³四川大学华西医院老年医学中心；⁴国家老年疾病临床医学研究中心；⁵北京医院 国家老年医学中心 中国医学科学院老年医学研究院；⁶华中科技大学同济医学院附属同济医院老年病科）

出处： 中华老年医学杂志 2022

关键词： 认知障碍；评估

摘要： 认知障碍是指因各种原因导致的不同程度的一个或多个认知域功能损害。认知障碍在老年人群中患病率高、危险因素多、病因复杂、危害性极大。对老年人进行认知障碍的早期筛查、早期诊断、早期干预具有重要意义, 但目前我国对老年认知障碍的识别率低、漏诊率高、评估不规范。本共识综合国内外常用的认知功能评估量表, 旨在推 ...

作者： Huanyu Gu;Yi Duan;Shanshan Li;Qin Wang;Wen Zhen;Wei Zhang;Yingying Zhang;Min Jiang;Chun Wang （Affiliations ¹ Department of Geriatrics, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China. ² Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China. ³ School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.）

出处： Acta biochimica et biophysica Sinica 2022

关键词： Smad3;Smad7;cardiac fibrosis;miR-96-5p;myocardial infarction.

摘要： Fibrotic remodelling contributes to heart failure in myocardial infarction. MicroRNAs (miRNAs) play a crucial role in myocardial fibrosis. However, cu ...

作者： Zhen-Xiong Zhao;|Yan-Qiu Zhang;|Hui Sun;|Zi-Qi Chen;|Jin-Jia Chang;|Xin Wang;|Xu Wang;|Cong Tan;|Shu-Juan Ni;|Wei-Wei Weng;|Meng Zhang;|Lei Wang;|Dan Huang;|Yun Feng;|Wei-Qi Sheng;|Mi-Die Xu （Affiliations ¹ Department of Gastric Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. ² Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China. ³ Department of Gastrointestinal Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. ⁴ Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. ⁵ Institute of Pathology, Fudan University, Shanghai, 200032, China. ⁶ Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200080, China. ⁷ Department of Gastroenterology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China. yun.feng2@shgh.cn. ⁸ Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China. shengwq@shca.org.cn. ⁹ Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. shengwq@shca.org.cn. ¹⁰ Institute of Pathology, Fudan University, Shanghai, 200032, China. shengwq@shca.org.cn. ¹¹ Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China. midiexu12@fudan.edu.cn. ¹² Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. midiexu12@fudan.edu.cn. ¹³ Institute of Pathology, Fudan University, Shanghai, 200032, China. midiexu12@fudan.edu.cn.）

出处： Acta pharmacologica Sinica 2022

关键词： IL-8;PI3K/AKT pathway;Vitamin D receptor;calcipotriol;cancer-associated fibroblasts;chemoresistance;gastric cancer;oxaliplatin;tumor microenvironment.

摘要： Activation of vitamin D receptor (VDR) in cancer-associated fibroblasts (CAFs) has been implicated in hesitating tumor progression and chemoresistance ...

作者： 束嘉俊，王智俊，朱亦丰，王丽佩，许冠吾 （上海市第一人民医院医保资金管理办公室）

出处： 中华医院管理杂志 2022

关键词： 疾病诊断相关分组；医院管理；社会网络分析；TOPSIS；熵权法

摘要： 目的明确我国医院在实施按疾病诊断相关分组（DRG）支付过程中需优先解决的管理问题, 为深化支付方式改革提供参考。方法以DRG、医院和管理等为检索词, 系统检索中国知网、万方数据库、PubMed、Embase和Web of Science从建库至2022年4月30日的文献资料, 从中提炼出DRG支付方 ...

作者： Zeng, Xiantao;Jin, Yinghui;Liu, Tongzu;Chen, Fangming;Ding, Degang;Fu, Meng;Gu, Xinquan;Han, Bangmin;Huang, Xing;Hou, Zhi;Hu, Wanli;Kang, Xinli;Li, Gonghui;Li, Jianxing;Li, Peijun;Liang, Chaozhao;Liu, Xiuheng;Liu, Zhiyu;Liu, Chunxiao;Liu, Jiumin;Luo, Guangheng;Luo, Yi;Qin, Weijun;Qiu, Jianhong;Qiu, Jianxin;Shang, Xuejun;Shi, Benkang;Sun, Fa;Tian, Guoxiang;Tian, Ye;Wang, Feng;Wang, Feng;Wang, Yinhuai;Wang, Yujie;Wang, Zhiping;Wang, Zhong;Wei, Qiang;Xiao, Minhui;Xu, Wanhai;Yi, Fa Xian;Zhu, Chaoyang;Zhuang, Qianyuan;Zhou, Liqun;Zou, Xiaofeng;Xing, Nianzeng;He, Dalin;Wang, Xinghuan （^aDepartment of Urology, Institute of Urology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China;^bCenter for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China;^cDepartment of Urology, Tianjin Third Central Hospital Affiliated To Nankai University, Tianjin, 300170, China;^dDepartment of Urology, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Zhengzhou, 450003, China;^eDepartment of Urology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China;^fDepartment of Urology, China-Japan Union Hospital of Jilin University, Changchun, 130033, China;^gDepartment of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China;^hDepartment of Urology, Qinghai University Affiliated Hospital, Xi’ning, 810012, China;ⁱDepartment of Urology, People’s Hospital of Hainan Province, Hainan Affiliated Hospital of Hainan Medical University Haikou, Haikou, 570311, China;^jDepartment of Urology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China;^kDepartment of Urology, General Hospital of Ningxia Medical University, Yinchuan, 750003, China;^lDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China;^mDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, 430060, China;ⁿDepartment of Urology, The Second Hospital of Dalian Medical University, Liaoning, Dalian, 116023, China;^oDepartment of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, 510282, China;^pDepartment of Urology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China;^qDepartment of Urology Surgery, Guizhou Province People’s Hospital, Guiyang, 550002, China;^rDepartment of Urology, Xijing Hospital of Air Force Military Medical University, Xi’an, 710032, China;^sDepartment of Urology, The 980St Hospital of the PLA Joint Logistics Support Force (Bethune International Peace Hospital of PLA), Shijiazhuang, 050082, China;^tDepartment of Urology, Tangdu Hospital, The Air Force Military Medical University, Xi’an, 710038, China;^uDepartment of Andrology, Jinling Hospital Affiliated to Nanjing University School of Medicine, Nanjing, 210002, China;^vDepartment of Urology, Qilu Hospital of Shandong University, Jinan, 250012, China;^wDepartment of Geriatrics, The Seventh Medical Center of Chinese, PLA General Hospital, Beijing, 100027, China;^xDepartment of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China;^yDepartment of Urology, People’s Hospital of Tibet Autonomous Region, Lhasa, 850000, China;^zDepartment of Urology, South China Hospital, Shenzhen University, Guangdong, Shenzhen, 518111, China;^aaDepartment of Urology, The Second Xiangya Hospital of Central South University, Changsha, 410011, China;^abDepartment of Urology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, China;^acDepartment of Urology, Institute of Urology, Lanzhou University Second Hospital, Key Laboratory of Urological Diseases in Gansu Province, Lanzhou, 730030, China;^adDepartment of Urology, Shanghai 9Th People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200011, China;^aeDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, 88 South Keyuan Road, Chengdu, 610041, China;^afDepartment of Urology, The First People’s Hospital of Yunnan Province, Kunming University of Science and Technology, Kunming, 650041, China;^agDepartment of Urology, The Fourth Hospital of Harbin Medical University, Heilongjiang Key Laboratory of Scientific Research in Urology, Harbin, 150001, China;^ahDepartment of Urology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010059, China;^aiDepartment of Urology, Huaihe Hospital of Henan University, Henan, Kaifeng, 475000, China;^ajDepartment of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China;^akDepartment of Urology, Peking University First Hospital, The Institute of Urology, Peking University, National Urological Cancer Center, Beijing, 100034, China;^alDepartment of Urology, First Affiliated Hospital of Gannan Medical University, Jiangxi, Ganzhou, 341000, China;^amDepartment of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China;^anDepartment of Urology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710061, China）

出处： Military Medical Research 2022

关键词： Benign prostatic hyperplasia;Guideline;Recommendation;Transurethral plasmakinetic resection of prostate;Treatment

摘要： Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, ...

作者： 王文雅，林江涛，刘春涛，唐华平，霍建民，顾玉海，刘荣玉，陈萍，袁雅冬，杨晓红，许建英，孙德俊，李娜嘉，姜淑娟，陈一强，王长征，杨岚，刘晓菊，杨冬，张伟，陈卓昌，林其昌，周建英，周新，胡成平，蒋萍，周玮，张捷，蔡绍曦，邱晨，黄茂，黄奕江，刘辉国 （中日友好医院呼吸与危重症医学科国家呼吸疾病临床研究中心；四川大学华西医院呼吸与危重症医学科；青岛市立医院呼吸与危重症医学科；哈尔滨医科大学第一附属医院呼吸科；青海省人民医院呼吸科；安徽医科大学第一附属医院呼吸与危重症医学科；北部战区总医院呼吸科；河北医科大学第二附属医院呼吸科；新疆维吾尔自治区人民医院呼吸与危重症医学科；山西白求恩医院呼吸与危重症医学科；内蒙古人民医院呼吸与危重症医学科；大庆油田总医院呼吸科；山东省人民医院呼吸与危重症医学科；广西医科大学第一附属医院呼吸内科；陆军医科大学新桥医院呼吸内科；西安交通大学附属第一医院呼吸与危重症医学科；兰州大学第一医院老年呼吸科；复旦大学附属中山医院呼吸内科；南昌大学第一附属医院呼吸内科；河南省人民医院呼吸内科；福建医科大学第一附属医院呼吸内科；浙江大学医学院附属第一医院呼吸内科；上海交通大学医学院附属上海市第一人民医院呼吸内科；中南大学湘雅医院呼吸与危重症医学科；天津市第一中心医院呼吸内科；宁夏医科大学总医院呼吸与危重症医学科；吉林大学第二医院呼吸与危重症医学科；南方科技大学附属南方医院呼吸与危重症医学科；暨南大学第二临床医学院深圳市人民医院呼吸与危重症医学科；南京医科大学附属第一医院呼吸与危重症医学科；海南省人民医院呼吸与危重症医学科；华中科技大学同济医学院附属同济医院呼吸内科；中国哮喘研究协作组）

出处： 中国呼吸与危重监护杂志 2022

关键词： 支气管哮喘；治疗依从性；哮喘控制；生活质量；肺功能

摘要： 目的 分析未控制的哮喘患者药物治疗依从性与肺功能、气道炎症水平、哮喘控制水平以及患者生活质量之间的关系,为改善患者依从性和提高哮喘控制水平提供依据。方法 以我国大陆28个省市32家三甲医院未达到哮喘控制且依从性差的哮喘患者作为研究对象,通过问卷调查的方式收集患者一般资料,所有患者均行肺功能、气道炎症 ...

作者： Wenmei Han;Wenli Wang;Jie Fan;Runping Jia;Xuchun Yang;Tong Wu;Qingsheng Wu （1. School of Chemical Science and Engineering, Shanghai Key Laboratory of Chemical Assessment and Sustainability, Institute of Advanced Study, Tongji University, Shanghai 200092, China; 2. College of Textile and Clothing Engineering, China National Textile and Apparel Council Key Laboratory of Natural Dyes, Soochow University, Suzhou 215123, China; 3. Department of Urology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, China; 4. School of Materials Science and Engineering, Shanghai Institute of Technology, Shanghai 201418, China）

出处： Green Energy&Environment 2022

关键词： Ag/ZnO hollow core-shell structures;antibiotics;gentamycin;synergistic sterilization;photodegradation

摘要： The massive use of antibiotics has led to the aggravation of bacterial resistance and also brought environmental pollution problems. This poses a grea ...

作者： Li, Sicong;Zhao, Ruiwei;Zou, Haidong （¹Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China ²Shanghai Eye Diseases Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China ³Fudan University, Shanghai, China ⁴Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China ⁵National Clinical Research Center for Eye Diseases, Shanghai 200080, China ⁶Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai 200080, China.）

出处： Chinese Medical Journal 2022

关键词： Artificial intelligence;Deep learning;Diabetic retinopathy

摘要： Diabetic retinopathy (DR) is an important cause of blindness globally, and its prevalence is increasing. Early detection and intervention can help cha ...

作者： Jian-Hong Wu;Dong-Ya Wang;Lu Sheng;Wei-Qing Qian;Shu-Jie Xia;Qi Jiang （¹Department of Urology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China ²Department of Urology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China ³Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China）

出处： Asian Journal of Andrology 2022

关键词： diabetes;endothelial nitric oxide synthase;erectile dysfunction;mesenchymal stem cells;vascular endothelial growth factor

摘要： Mesenchymal stem cells (MSCs) secrete various cytokines with angiogenic and neuroprotective effects. This study aimed to assess the effects of human u ...

作者： Chuan Huang;Yu-Lin Tang;Jian-Ling Hu;Wen-Jun Zhou;Zeng-Hui Huang;Xue-Feng Luo;Zheng Li;Wen-Bing Zhu （Affiliations ¹ Institute of Reproductive and Stem Cell Engineering, Basic Medicine College, Central South University, Changsha 410000, China. ² Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410000, China. ³ Department of Andrology, Center for Men's Health, Shanghai General Hospital, Shanghai Key Lab of Reproductive Medicine, Shanghai 200025, China.）

出处： Asian journal of andrology 2022

关键词： cryodamage;cryoprotectant;dry preservation;freezing and thawing;sperm cryopreservation.

摘要： In the 1960s, sperm cryopreservation was developed as a method to preserve fertility. Currently, techniques for the cryopreservation of human spermato ...