作者： 凌林，李岩，胡芳宝，窦红杰，王文 （上海交通大学附属第一人民医院急诊危重病科；上海市奉贤区中心医院重症医学科）

出处： 现代生物医学进展 2023

关键词： 劳力性热射病；TNF-α；HMGB1；CCL5；预后；影响因素；预测价值

摘要： 目的:探讨劳力性热射病(EHS)患者预后的影响因素,并分析入院时血清肿瘤坏死因子-α(TNF-α)、高迁移率族蛋白1(HMGB1)、CC类趋化因子5(CCL5)对该病患者死亡风险的预测价值.方法:选取2018年5月～2022年4月我院收治的50例EHS患者,入院时均以酶联免疫吸附试验完善血清TNF- ...

作者： Deng Zhenan¹，Jin Meiling¹⁰，Ou Changxing¹³，Jiang Wei¹⁵，Zhao Jianping¹⁰，Liu Xiaoxia¹⁰，Sun Shenghua¹⁰，Tang Huaping¹⁰，He Bei¹⁰，Cai Shaoxi¹⁰，Chen Ping¹⁰，Wu Penghui¹，Liu Yujing¹⁵，Kang Jian¹⁰，Zhang Yunhui¹⁰，Huang Mao¹⁰，Xu Jinfu¹⁰，Huang Kewu¹⁰，Li Qiang¹⁰，Zhang Xiangyan¹⁰，Fu Xiuhua¹⁰，Wang Changzheng¹⁰，Shen Huahao¹⁰，Zhu Lei¹⁰，Shi Guochao¹⁰，Qiu Zhongmin⁶⁵，Wen Zhongguang¹⁰，Wei Xiaoyang⁷¹，Gu Wei⁷³，Wei Chunhua¹⁰，Wang Guangfa¹⁰，Chen Ping¹⁰，Xie Lixin⁸³，Lin Jiangtao¹⁰，Tang Yuling¹⁰，Han Zhihai⁹⁰，Chung Kian Fan⁹²，Zhang Qingling¹，Zhong Nanshan¹ （¹Pulmonary and Critical Care Medicine；²Guangzhou Institute of Respiratory Health；³National Clinical Research Center for Respiratory Disease；⁴National Center for Respiratory Medicine；⁵State Key Laboratory of Respiratory Diseases；⁶The First Affiliated Hospital of Guangzhou Medical University；⁷Guangzhou；⁸Guangdong 510120；⁹China；¹⁰Department of Respiratory Medicine；¹¹Zhongshan Hospital；¹²Shanghai 200433；¹³Guangzhou Medical University；¹⁴Guangdong 510180；¹⁵AstraZeneca；¹⁶Shanghai 200085；¹⁷Tongji Hospital；¹⁸Tongji Medical College；¹⁹Huazhong University of Science and Technology；²⁰Wuhan；²¹Hubei 430030；²²Beijing Friendship Hospital；²³Capital Medical University；²⁴Beijing 100050；²⁵The Third Xiangya Hospital of Central South University；²⁶Changsha；²⁷Hunan 410013；²⁸Qingdao Municipal Hospital；²⁹Qingdao；³⁰Shandong 266001；³¹Peking University Third Hospital；³²Beijing 100191；³³Nanfang Hospital of Southern Medical University；³⁴Guangdong 510515；³⁵General Hospital of Northern Theater Command；³⁶Shenyang；³⁷Liaoning 110016；³⁸The First Hospital of China Medical University；³⁹Liaoning 110001；⁴⁰The First people’s Hospital of Yunnan Province；⁴¹Kunming；⁴²Yunnan 363880；⁴³The First Affiliated Hospital of Nanjing Medical University；⁴⁴Nanjing；⁴⁵Jiangsu 210029；⁴⁶Shanghai Pulmonary Hospital；⁴⁷Beijing Chao-Yang Hospital；⁴⁸Beijing 100020；⁴⁹Shanghai General Hospital；⁵⁰Shanghai 200080；⁵¹Guizhou Province People’s Hospital；⁵²Guiyang；⁵³Guizhou 550002；⁵⁴The Affiliated Hospital of Inner Mongolia Medical University；⁵⁵Huhhot；⁵⁶Inner Mongolia 010050；⁵⁷The Third Affiliated Hospital of Chongqing Medical University；⁵⁸Chongqing 401120；⁵⁹The Second Affiliated hospital of Zhejiang University School of Medicine；⁶⁰Hangzhou；⁶¹Zhejiang 310003；⁶²Ruijin Hospital；⁶³Shanghai Jiaotong University School of Medicine；⁶⁴Shanghai 200025；⁶⁵Department of Pulmonary and Critical Care Medicine；⁶⁶School of Medicine；⁶⁷Tongji University；⁶⁸Shanghai 200065；⁶⁹The First Affiliated Hospital of PLA General Hospital；⁷⁰Beijing 100048；⁷¹Department of Respiratory and Critical Care Medicine；⁷²The Eighth Medical Center of PLA General Hospital；⁷³Department of Respiratory；⁷⁴Nanjing First Hospital；⁷⁵Nanjing Medical University；⁷⁶Weifang Weien Hospital；⁷⁷Weifang；⁷⁸Shandong 261045；⁷⁹Peking University First Hospital；⁸⁰Beijing 100034；⁸¹The Second Xiangya Hospital of Central South University；⁸²Hunan 410011；⁸³College of Pulmonary and Critical Care Medicine；⁸⁴Chinese PLA General Hospital；⁸⁵Beijing 100853；⁸⁶China-Japan Friendship Hospital；⁸⁷Beijing 100029；⁸⁸The First Hospital of Changsha；⁸⁹Hunan 410005；⁹⁰Deparment of Pulmonary and Critical Care Medicine；⁹¹The Sixth Medical Center of PLA General Hospital；⁹²National Heart and Lung Institute；⁹³Imperial College London；⁹⁴London SW3；⁹⁵UK）

出处： 中华医学杂志英文版 2023

作者： 吕牧，楼利群，余娟娟，罗伊凡，黄宝珠，覃祚树，张箴波 （上海交通大学附属第一人民医院妇产科）

出处： 现代生物医学进展 2023

关键词： KANK1；子宫内膜癌；细胞周期；凋亡；细胞迁移

摘要： 目的：研究KANK1在子宫内膜癌中的表达以及对子宫内膜癌细胞增殖及迁移的影响。方法：（1）TCGA数据库分析KANK1在子宫内膜癌中的表达和生存期分析。（2）采用实时荧光定量聚合酶链反应验证转染KANK1质粒的效果。采用Ishikawa和ECC1这两种子宫内膜癌细胞来探讨KANK1对子宫内膜癌的细胞 ...

作者： Wei Yong¹，Zhou Genqing¹，Wu Xiaoyu¹，Lu Xiaofeng¹，Wang Xingjie⁶，Wang Bin⁸，Wang Caihong¹⁰，Shen Yahong¹²，Peng Shi¹，Ding Yu¹，Xu Juan¹，Cai Lidong¹，Chen Songwen¹，Yang Wenyi¹，Liu Shaowen¹ （¹Department of Cardiology；²Shanghai General Hospital；³Shanghai Jiao Tong University School of Medicine；⁴Shanghai 200080；⁵China；⁶Shihudang Community Health Care Center；⁷Shanghai 201604；⁸Dongjing Community Health Care Center；⁹Shanghai 201619；¹⁰Xinbang Community Health Care Center；¹¹Shanghai 201605；¹²Maogang Community Health Care Center；¹³Shanghai 201607）

出处： 中华医学杂志英文版 2023

关键词： Atrial fibrillation；Incidence；Predictor；Electrocardiogram

摘要： Background: China bears the biggest atrial fibrillation （AF） burden in the world. However, little is known about the incidence and predictors of AF. T ...

作者： 师晓琴，徐宵宵，何金，蒋立人，蔡毅然 （上海市第一人民医院病理科）

出处： 同济大学学报(医学版) 2023

关键词： 甲状腺乳头状癌；细针抽吸活检； BRAF； ARMS-PCR

摘要： 目的 评价以新鲜穿刺样本和经苏木精-伊红(HE)染色后的细胞样本作为甲状腺穿刺鼠类肉瘤滤过性毒菌致癌同源体B1(BRAF)基因V600突变检测样本的适用性。方法 收集370例甲状腺乳头状癌(papillary thyroid carcinoma, PTC)患者的临床资料,及术前细针穿刺(fine-n ...

作者： 喻蓉，沈崔琴，陈建雄，沙蕾，曹萌萌，杜联芳，李朝军 （上海市嘉定区南翔医院超声科；上海市第一人民医院嘉定医院超声科；福建医科大学附属闽东医院超声科；上海交通大学医学院附属第一人民医院超声医学科）

出处： 同济大学学报(医学版) 2023

关键词： 超声心动图；2型糖尿病； 高血压；环向应变； 二维斑点追踪技术

摘要： 目的 探讨2型糖尿病(T2DM)合并高血压患者左心室心肌环向应变与10年心血管病风险的关系。方法 收集T2DM患者83例,以是否合并高血压分为糖尿病组(DM组)和糖尿病合并高血压组(DM+HBP组),选取同期住院患者54例为对照组。依据Framingham危险评分量表计算危险评分(FRS)和10年心 ...

作者： Xiang Wang，Cheng Ding，Ziwen Zhang，Chunlin Li，Dongmiao Cao，Linjing Zhao，Guoying Deng，Yu Luo，Chunping Yuan，Jie Lu，Xijian Liu （School of Chemistry and Chemical Engineering, Shanghai Engineering Technology Research Center for Pharmaceutical Intelligent Equipment, Shanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science；Affiliated Sixth People’s Hospital, Shanghai JiaoTong University；Trauma Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine）

出处： Chinese Chemical Letters 2023

关键词： Self-cascade；reaction Starvation；therapy；Chemodynamic；therapy；Antitumor；Antibacterial；Wound；healing

摘要： Diabetic patients often have problems such as residual tumor and wound infection after tumor resection,causing severe clinical problems.It is urgent t ...

作者： Xu Hongjiao¹，Wang Zhaomin¹，Peng Zhongmei¹，Zhang Jianhai¹，Li Xiang¹，Liu Di¹，Qi Jie¹，Li Jinbao¹ （¹Department of Anesthesiology；²Shanghai Jiaotong University First People’s Hospital (Shanghai General Hospital)；³Shanghai 200080；⁴China）

出处： 中华医学杂志(英文版) 2023

作者： 谢林，吴凌恒，陈建雄，孙佳丽，陆敏，胡浩清，杜联芳，李朝军 （嘉定区中医医院超声科；上海市第一人民医院嘉定分院超声科；福建医科大学附属闽东医院超声科；嘉定区中心医院超声科；上海交通大学医学院附属第一人民医院超声医学科）

出处： 中国医学影像技术 2023

关键词： 高血压；心力衰竭,舒张期； 应变； 超声心动描记术

摘要： 目的 观察左心室心肌应变参数用于预测初诊及未经治疗高血压患者射血分数保留性心力衰竭(HFpEF)的价值。方法 纳入105例初诊或未经治疗原发性高血压伴HFpEF患者(HFpEF组)和131名健康志愿者(对照组),比较组间左心室结构、功能和心肌应变参数,包括舒张末期左心室内径(LVEDD)、收缩末期左 ...

作者： Jiao Feng¹，Cui Jiujie¹，Fu Deliang⁹，Li Qi¹，Wu Zheng¹⁵，Teng Zan¹，Zhang Hongmei²²，Zhou Jun²⁵，Zhang Zhihong²⁹，Chen Xiaobing¹，Zhou Yuhong²²，Li Yixiong³⁹，Mou Yiping⁴⁴，Qin Renyi⁵⁰，Sun Yongwei⁵⁰，Jin Gang⁵⁶，Cheng Yuejuan²²，Wang Jian⁶³，Ren Gang⁶⁶，Yue Jiang⁶⁹，Jin Guangxin⁷⁰，Xiao Xiuying¹，Wang Liwei¹ （¹Department of Oncology；²State Key Laboratory of Systems Medicine for Cancer；³Shanghai Cancer Institute；⁴Renji Hospital；⁵School of Medicine；⁶Shanghai Jiao Tong University；⁷Shanghai 200127；⁸China；⁹Department of Pancreatic Surgery；¹⁰Huashan Hospital；¹¹Fudan University；¹²Shanghai 200040；¹³Shanghai General Hospital；¹⁴Shanghai 200080；¹⁵Department of Hepatobiliary Surgery；¹⁶The First Affiliated Hospital of Xi’an Jiao Tong University；¹⁷Xi’an；¹⁸Shaanxi 710061；¹⁹The First Hospital of China Medical University；²⁰Shenyang；²¹Liaoning 110801；²²Department of Medical Oncology；²³The First Affiliated Hospital of Air Force Medical University；²⁴Shaanxi 710032；²⁵Department of Gastrointestinal Oncology；²⁶Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing)；²⁷Peking University Cancer Hospital and Institute；²⁸Beijing 100142；²⁹Department of Pathology；³⁰The First Affiliated Hospital of Nanjing Medical University；³¹Nanjing；³²Jiangsu 210029；³³The Affiliated Cancer Hospital of Zhengzhou University；³⁴Henan Cancer Hospital；³⁵Zhengzhou；³⁶Henan 450003；³⁷Zhongshan Hospital；³⁸Shanghai 200032；³⁹Department of General Surgery；⁴⁰Xiangya Hospital；⁴¹Central South University；⁴²Changsha；⁴³Hunan 410008；⁴⁴Department of Gastrointestinal and Pancreatic Surgery；⁴⁵Zhejiang Provincial People’s Hospital；⁴⁶Affiliated People’s Hospital；⁴⁷Hangzhou Medical College；⁴⁸Hangzhou；⁴⁹Zhejiang 310014；⁵⁰Department of Biliary-Pancreatic Surgery；⁵¹Affiliated Tongji Hospital；⁵²Tongji Medical College；⁵³Huazhong University of Science and Technology；⁵⁴Wuhan；⁵⁵Hubei 430030；⁵⁶Department of Hepatobiliary Pancreatic Surgery；⁵⁷Changhai Hospital；⁵⁸Naval Medical University；⁵⁹Shanghai 200433；⁶⁰Peking Union Medical College Hospital；⁶¹Chinese Academy of Medical Sciences and Peking Union Medical College；⁶²Beijing 100730；⁶³Department of Radiology；⁶⁴Shanghai Changzheng Hospital；⁶⁵Shanghai 200003；⁶⁶Department of Radiotherapy；⁶⁷Peking University Shougang Hospital；⁶⁸Beijing 100144；⁶⁹Department of Endocrinology and Metabolism；⁷⁰Department of Interventional Oncology）

出处： 中华医学杂志英文版 2023