作者： Mengqing,Zhang ;Chao,Li ;Fang,Zhang ;Xiaoxiao,Han ;Qinglu,Yang ;Tuo,Lin ;Huichang,Zhou ;Min,Tang ;Jungui,Zhou ;Hongling,Shi ;Yanping,Hui ;Mingfeng,Xiong ;Ling,Pang ;Baolan,Wang ;Zhen,Feng ;Zhanfei,Li ;Changbing,Cao ;Xiao,Lu ;Yuanyuan,Ding ;Shukun,Shen ;Zhengyue,Xu ;Fan,Yu ;Chen,Chen ;Ling,Meng ;Guiqing,Liao ;Jinxin,Zhang ;Ayodele,Sasegbon ;Zulin,Dou （Department of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, No. 600, Tianhe Road, Guangzhou, 510630, Guangdong, China. \'(1)\' ; Department of Rehabilitation Medicine, Guangzhou First People\'s Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China. [2] ; Department of Rehabilitation Medicine, The First People\'s Hospital of Foshan, Foshan, Guangdong, China. [3] ; Department of Neurological Rehabilitation Medicine, Ningbo Rehabilitation Hospital, Ningbo, Zhejiang, China. [4] ; Department of Rehabilitation Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangzhou, Guangdong, China. [5] ; Department of Rehabilitation Medicine, Third People\'s Hospital of Yunnan Province, Kunming, Yunnan, China. [6] ; Department of Rehabilitation Medicine, The Second Affiliated Hospital, Xi\'an Jiaotong University School of Medicine, Xi\'an, Shanxi, China. [7] ; Department of Rehabilitation Medicine, First Affiliated Hospital of Army Medical University, Chongqing, China. [8] ; Department of Rehabilitation Medicine, China-Japan Union Hospital of Jilin University, Jilin, Changchun, China. [9] ; Department of Rehabilitation Medicine, The First Affiliated Hospital of Xinjiang University and Xinjiang Medical University, Urumqi, Xinjiang, China. [10] ; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. [11] ; Department of Rehabilitation Medicine, Affiliated Hospital of Qingdao University, Qingdao, Shandong, China. [12] ; Department of Rehabilitation Medicine, Fujian Longyan Longgang Hospital, Longyan, Fujian, China. [13] ; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. [14] ; Department of Rehabilitation Medicine, Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [15] ; Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [16] ; Department of Rehabilitation Medicine, Qinghai Provincial People\'s Hospital, Xining, Qinghai, China. [17] ; Department of Rehabilitation Medicine, Shanghai General Hospital, Shanghai, China. [18] ; Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China. [19] ; Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. [20] ; Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China. [21] ; Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China. [22] ; Division of Diabetes, Endocrinology and Gastroenterology, Faculty of Biology, Medicine and Health, Centre for Gastrointestinal Sciences, School of Medical Sciences, The University of Manchester, Clinical Sciences Building, Salford Royal NHS Foundation Trust, Manchester, UK. [23] ; Department of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen University, No. 600, Tianhe Road, Guangzhou, 510630, Guangdong, China. douzul@163.com. [24]）

出处： Dysphagia

关键词： Chinese elderly;Comorbidity;Deglutition;Deglutition disorders;Dysphagia;Epidemiology

摘要： To determine the prevalence of dysphagia among an older population and patients with stroke, head and neck cancers (HNCs) or neurodegenerative disease ...

作者： Beibei,Jiang ;Ning,Guo ;Yinghui,Ge ;Lu,Zhang ;Matthijs,Oudkerk ;Xueqian,Xie （Radiology Department \'(1)\' ; Shanghai General Hospital [2] ; Shanghai Jiao Tong University School of Medicine [3] ; Haining Rd.100 [4] ; Shanghai 200080 [5] ; China. [6] ; Shukun (Beijing) Technology Co [7] ; Ltd. [8] ; Jinhui Bd [9] ; Qiyang Rd [10] ; Beijing 100102 [11] ; Central China Fuwai Hospital [12] ; Fuwai Avenue 1 [13] ; Zhengzhou 450046 [14] ; Institute for DiagNostic Accuracy [15] ; Prof. Wiersma Straat 5 [16] ; 9713GH Groningen [17] ; The Netherlands. [18] ; University of Groningen [19] ; Faculty of Medical Sciences [20] ; 9700AB Groningen [21]）

出处： The British journal of radiology P20190812

摘要： In this review, we describe the technical aspects of artificial intelligence (AI) in cardiac imaging, starting with radiomics, basic algorithms of dee ...

作者： Zhongquan Zhou;Songwen Chen;Zhiming Tian;Shibing Deng;Xuying Yi;Shaning Yang;Xuexin Yang;Lijun Jin;Wanqing Shi （Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, Shanghai General Hospital, Shanghai 200000, China Department of Cardiology, First School of Clinical Medicine College, Yangtze University, Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China The First Hospital of Jingzhou City, The Interventional Center, Jingzhou 434000, China）

出处： Acta Biochimica et Biophysica Sinica

关键词： hypoxia-inducible factor-1;cardiomyocytes;hypoxia;miR-20b-5p;NF-κB

摘要： Chronic hypoxia is a common inducer of end-stage cardiovascular disease. In cells under hypoxia, the hypoxia-inducible factor-1 (HIF-1) plays a vital ...

作者： Shuyu,Xiong ;Xiangui,He ;Bo,Zhang ;Junjie,Deng ;Jingjing,Wang ;Minzhi,Lv ;Jianfeng,Zhu ;Haidong,Zou ;Xun,Xu （Department of Preventative Ophthalmology \'(1)\' ; Shanghai Eye Disease Prevention and Treatment Center [2] ; Shanghai Eye Hospital [3] ; Shanghai [4] ; China; Department of Ophthalmology [5] ; Shanghai Key Laboratory of Ocular Fundus Disease [6] ; Shanghai General Hospital [7] ; Shanghai Engineering Center for Visual Science and Photomedicine [8] ; Shanghai Jiao Tong University [9] ; China. [10] ; China. Electronic address: xianhezi@163.com. [11]）

出处： American journal of ophthalmology

摘要： To clarify the changing characteristics of choroidal thickness over time within different age ranges and among different refractive statuses of childr ...

作者： Xieyi Yao¹;Chong Chen¹;Jian Zhang¹;Yupeng Xu¹;Shuyu Xiong¹;Qing Gu¹;Xun Xu¹CA1;Yan Suo² （1 a Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;b National Clinical Research Center for Eye Diseases, Shanghai, China;c Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China;d Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China;e Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China; 2 a Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;b National Clinical Research Center for Eye Diseases, Shanghai, China;c Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai, China;f Shanghai Eye Diseases Prevention and Treatment Center/Shanghai Eye Hospital, Shanghai, China）

出处： Current Eye Research

关键词： Peptide;neurotrypsin;kringle;NT/K-CFY;neovascularization

摘要： Purpose : To assess the anti-neovascularization effect of a novel peptide NT/K-CFY derived from the kringle domain of neurotrypsin. Materials and M ...

作者： Cai-Guo Yu;Fang-Fei Wei;Zhen-Yu Zhang;Lutgarde Thijs;Wen-Yi Yang;Blerim Mujaj;Ying-Mei Feng;José Boggia;Harry A. Roels;Harry A. J. Struijker-Boudier;Tim S. Nawrot;Peter Verhamme;Jan A. Staessen （Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; ; Department of Endocrinology, Beijing Luhe Hospital and, Key Laboratory of Diabetes Prevention and Research, Capital Medical University, Beijing, China; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; ; Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Department of Endocrinology, Beijing Luhe Hospital and, Key Laboratory of Diabetes Prevention and Research, Capital Medical University, Beijing, China; Unidad de Hipertensión Arterial, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium; Department of Pharmacology, Maastricht University, Maastricht, The Netherlands; Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium; Centre for Molecular and Vascular Biology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium; ; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands）

出处： Blood Pressure

关键词： arterial stiffness;central blood pressure;central hemodynamics;lead;environmental medicine

摘要： Purpose: Arterial stiffness predicts cardiovascular complications. The association between arterial stiffness and blood lead (BL) remains poorly docum ...

作者： X. Zhu;Y. Xu;X. Xu;J. Zhu;X. He;L. Lu;H. Zou （Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China;Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China;Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China;Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China;Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China;Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China;Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China;Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China）

出处： Diabetic Medicine

摘要： Aim To translate the Compliance with Annual Diabetic Eye Exams Survey (CADEES) into Chinese, allowing assessment of its reliability and validity, and ...

作者： Xin-Yun Zhang;Jian-Wen Sun;Zhong-Ling Qiu;Yang Wang;Xiao-Yue Chen;Jin-Hua Zhao;Quan-Yong Luo （1.Department of Nuclear Medicine,Shanghai Jiao Tong University Affiliated Sixth People’s Hospital,Shanghai,China;2.Department of Nuclear Medicine,Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai,China）

出处： Endocrine P1-12

关键词： Differentiated thyroid carcinoma;Distant metastases;Multiple distant organ system metastases;Radioactive iodine therapy;Overall survival

摘要： Objectives For patients with differentiated thyroid carcinoma (DTC), distant metastases are commonly identified in the lungs and bones. However, they ...

作者： Kun,Wang ;Jiaxing,Sun ;Wei,Gao ;Rongzhang,Chen ;Xiaodong,Wu ;Yanan,He ;Qian,Guo ;Xin,Zhang ;Qiang,Li （Department of Pulmonary and Critical Care Medicine \'(1)\' ; Shanghai General Hospital [2] ; Shanghai Jiao Tong University School of Medicine [3] ; Shanghai [4] ; 201620 [5] ; China; Department of Pulmonary and Critical Care Medicine [6] ; Shanghai East Hospital [7] ; Tongji University [8] ; 200120 [9] ; China. [10] ; People\'s Liberation Army Joint Logistic Support Force 920th Hospital [11] ; China. Electronic address: derekzhang2008@163.com. [12] ; China. Electronic address: liqressh1962@163.com. [13]）

出处： Cryobiology

关键词： Animal model;Chronic obstructive pulmonary disease;Cryo-balloon;Targeted lung denervation

摘要： Targeted lung denervation (TLD) is a pulmonary interventional procedure for COPD that aims to disrupt parasympathetic nerve input to the lung to reduc ...

作者： Miao,Yu ;Zhi-Xiao,Fang ;Wei-Wei,Wang ;Ying,Zhang ;Zhi-Lei,Bu ;Meng,Liu ;Xin-Hua,Xiao ;Zi-Lu,Zhang ;Xing-Ming,Zhang ;Yang,Cao ;Ying-Ying,Wang ;Hu,Lei ;Han-Zhang,Xu ;Yun-Zhao,Wu ;Wei,Liu ;Ying-Li,Wu （Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. \'(1)\' ; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic MedicineChemical Biology Division of Shanghai Universities E-Institutes, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. [2] ; Department of Hematology, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. [3] ; Department of Transfusion Medicine, Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. [4] ; Department of Hematology, The Third Affiliated Hospital of Soochow University, The First People\'s Hospital of Changzhou, Changzhou, 213003, China. [5] ; Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. bsjys@shsmu.edu.cn. [6] ; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic MedicineChemical Biology Division of Shanghai Universities E-Institutes, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. wuyingli@shsmu.edu.cn. [7]）

出处： Acta pharmacologica Sinica

关键词： AML;AMPKα;Compound C;FLT3-ITD;USP10;Wu-5;crenolanib;metformin

摘要： The kinase FLT3 internal tandem duplication (FLT3-ITD) is related to poor clinical outcomes of acute myeloid leukemia (AML). FLT3 inhibitors have prov ...