许迅
详细
发明人: 许迅,柯潇,郑颖,罗德伦,邬智刚
申请人: 上海市第一人民医院,成都康弘药业集团股份有限公司
申请号: 201310323096.0
申请日期: 2013.07.29
摘要: 本发明涉及一类新的抑制血管新生的多肽及其应用。本发明还涉及所述多肽的制法和应用以及含所述多肽的药物组合物。本发明多肽具有多种优点,例如分子量小,可透过各种眼组织屏障;水溶性好,能在中性泪液、房水和玻璃体液中保持较高的浓度等。
作者: Luo, Dawei;Fan, Ying;Xu, Xun
出处: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2012 Vol.22 No.13 P4386-4390
摘要: Background: The accumulation of advanced glycated end products (AGEs) in retinal blood vessels is one of the major etiological factors contributing to ...
作者: Wang Ning;Zheng Zhi;Jin Hui-yi;Xu Xun
出处: CHINESE MEDICAL JOURNAL 2012 Vol.125 No.2 P287-292
摘要: Background Diabetic retinopathy (DR) is one of the most common complications of diabetes. Angiotensin-converting enzyme inhibitor is thought to play a ...
发明人: Xu Xun;Zheng Ying
申请人: SHANGHAI FIRST PEOPLE'S HOSPITAL
申请号: US201214370114
申请日期: 2012.10.29
摘要: Provided is a polypeptide having angiogenesis inhibiting activity. The polypeptide is derived from Placenta Growth Factor-1. Also provided are a deriv ...
作者: 唐敏,傅扬,富名水 (上海交通大学附属第一人民医院眼科 (200080))
出处: 中华眼外伤职业眼病杂志 2012 第34卷 第3期 P188-192
关键词: Ahmed青光眼引流阀 小梁切除术 巩膜扣带术 青光眼
作者: Zheng, Ying;Gu, Qing;Xu, Xun
出处: ACTA OPHTHALMOLOGICA 2012 Vol.90 No.7 PE512-E523
摘要: Purpose: To evaluate the effect of ZY1, a novel 21-amino acid peptide from human placenta growth factor-1 (PlGF-1), against ocular neovascularization, ...
作者: Wang Haiyan;Gu Qing;Xu Xun
出处: Chinese Medical Journal 2012 Vol.125 No.13 P2310-2315
摘要: Background Methanesulfonic acid sodium salt (Dipyrone), an antipyretic and analgesic drug, has been demonstrated to improve cerebral ischemia through ...
作者: Jun LI,Shu-zhi ZHAO,Pei-pei WANG,Song-ping YU,Zhi ZHENG,Xun XU (Department of Ophthalmology,Shanghai First People\'s Hospital Affiliated Shanghai Jiao Tong University,Shanghai 200080,China;Department of Ophthalmology,Lishui City Center Hospital,Lishui 323000,China)
出处: 中国药理学报(英文版) 2012 第8期 P1030-1036
关键词: diabetic;retinopathy;hyperglycemia;retinal;M(u)iler;cells;intracellular;Ca2+;CaMKII;CREB
作者: Zhang, Zhi-Hua;Liu, Hai-Yun;Wimpissinger, Barbara;Avitabile, Teresio;Xu, Xun;Liu, Kun
出处: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 2013 Vol.251 No.3 P681-688
摘要: Transconjunctival sutureless vitrectomy is appealing to vitreoretinal surgeons around the world. However, its use versus 20-gauge vitreoretinal surger ...
作者: Zou, Haidong;Liu, Haiyun;Xu, Xun;Zhang, Xi
出处: QUALITY OF LIFE RESEARCH 2013 Vol.22 No.6 P1507-1514
摘要: To assess the time trade-off (TTO) utility values in patients with persistent visually disabling vitreous floaters (DVF) and to determine the reliabil ...