【摘要】The invention, belonging to the field of biomedicine and bio-polymer material, particularly relates to an anti-benign and malignant biliary stricture drug eluting stent and a preparation method thereof. The stent is prepared by coating a biodegradable polymer layer containing anti-malignant biliary stricture drug mitomycin or/and paclitaxel on the inner surface and outer surface of a bare bile duct stent. Clinical outcomes show that the anti-benign and malignant biliary stricture drug eluting stent of the invention has good radial supporting performance, can prevent benign and malignant biliary proliferation and stricture from occlusion and keep the bile duct smooth, has good biocompatibility, and generates almost no internal inflammation. Simultaneously, mitomycin or/and paclitaxel slowly released by the polymer layer can resist benign and malignant biliary proliferation and stricture, and prevent aggravation of biliary obstruction caused by bile duct proliferation and then stricture after stent implantation.
