【摘要】The invention belongs to the biologic medicine filed and relates to a novel gene therapy compound preparation and the use and application method thereof. When adeno-associated virus is used as gene delivery carrier, a certain dose of adriamycin is combined in use, and obviously advances expression time of foreign gene mediated by adeno-associated virus, obviously increases the transfer efficiency and gene expression level, and prolongs expression time. The experiment result indicates that the compound preparation does not have obvious toxic and side effects on cells. The compound preparation and application method thereof can be used in instructing and assisting gene therapy for ophthalmopathy, genetic disease and tumor.
