你好,欢迎访问上海交通大学附属第一人民医院公济文库!
  • MicroRNA (ribonucleic acid) specific expression profile and application thereof

  • 【作者】ZHIHAI PENG;ZHONGBO HAN;JUNWEI FAN
  • 【年份】2011
  • 【卷号】SHANGHAI FIRST PEOPLE S HOSPITAL
  • 【页码】CN102586412;|2012.07.18
  • 【ISSN】CN2011100219053
  • 【分类号】C12Q1/68
  • 【摘要】The invention belongs to the fields of biological and medical examination, and relates to microRNA (ribonucleic acid) specific expression profile and clinical application thereof. Tumor recurrence after liver transplantation for liver cancer can be judged by five miRNAs or comprehensive indexes of the microRNA specific expression profile, accuracy rate reaches 77%, further, tumor recurrence and prognosis conditions of an integral case group can be judged, tumor recurrence and prognosis conditions can also be judged for patients after Milan delamination of the patients by the aid of the 5 miRNAs or the comprehensive indexes, accordingly, the microRNA specific expression profile can be used for screening patients with high tumor recurrence risks after clinical liver transplantation for liver cancer, assists in judging prognosis and realizing early diagnosis of recurrence, and provides a basis for early intervention treatment and implementation of individualized treatment.
  • 【文献类型】外文专利

  • 进入大医系统查看更多信息