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  • Toosendanin demonstrates promising antitumor efficacy in osteosarcoma by targeting STAT3

  • 【作者】Zhang, T.;Li, J.;Yin, F.;Lin, B.;Wang, Z.;Xu, J.;Wang, H.;Zuo, D.;Wang, G.;Hua, Y.;Cai, Z.
  • 【出处】ONCOGENE
  • 【年份】2017
  • 【卷号】Vol.36 No.47
  • 【页码】6627-6639
  • 【ISSN】0950-9232
  • 【分类号】616.994
  • 【摘要】Signal transducer and activator of transcription 3(STAT3) is an emerging target for cancer therapy. In this study, we identify Toosendanin (TSN) is an effective inhibitor of STAT3, leading to the impediment of various oncogenic processes in osteosarcoma.
  • 【文献类型】外文期刊

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