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  • Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma

  • 【作者】Yang, Hao;Zhu, Rongxuan;Zhao, Xiaoping;Liu, Liu;Zhoul, Zhaoli;Zhao, Li;Liang, Beibei;Ma, Wenjing;Zhao, Jian;Liu, Jianjun;Huang, Gang
  • 【出处】ONCOGENE
  • 【年份】2019
  • 【卷号】Vol.38 No.25
  • 【页码】4915-4931
  • 【ISSN】0950-9232
  • 【分类号】616.994
  • 【摘要】Tumor cells undergo a metabolic shift in order to adapt to the altered microenvironment, although the underlying mechanisms have not been fully explored. HnRNP A1 is involved in the alternative splicing of the pyruvate kinase (PK) mRNA, allowing tumor cel
  • 【文献类型】外文期刊

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