【摘要】The objective of this paper is to study the renal arteriovenous transit time (RAVTT) of ultrasound contrast agent (SonoVue) in healthy adults, and to discuss the value of RAVTT in evaluating renal function by comparing the time between patients with normal or abnormal renal function (2 stage of nephropathy). Sixty-nine patients were examined by baseline ultrasonography, and underwent contrast-enhanced ultrasonography, after injection of SonoVue into the ulnar vein, then the arrival time (AT) of the contrast echoes in the renal portal artery and renal portal vein was analyzed. There was no significant difference of RAVTT between healthy adult group and patients group with renal benign or malignant space-occupying lesion. However, RAVTT of patients with 2 stages of nephropathy was distinctively longer (4.39plusmn0.37 s) than that of the normal patients (P<0.05). RAVTTles4 s was found in all patients with normal renal function. RAVTT of SonoVue in healthy adults is (2.70plusmn0.16) s, which provides a reference for following study. RAVTT in patients group with 2 stage of nephropathy is (4.39plusmn0.37) s. Renal arteriovenous transit time measurement could be used to preliminarily evaluate renal function by offering volume and velocity information of renal blood flow
