【作者单位】1 State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai, China 2 College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, China 3 Department of Orthopedics, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China 4 Department of Radiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China 5 Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China
【出处】Advanced Healthcare Materials
【年份】2014
【卷号】Vol.3 No.10
【页码】1522
【关键词】multiwalled carbon nanotubes;polyethyleneimine;PEGylation;blood pool MR imaging;tumor MR imaging
【ISSN】2192-2640
【摘要】Long-circulating multifunctional Gd(III)-loaded multiwalled carbon nanotubes (MWCNTs) modified with polyethylene glycol are designed and synthesized by W. Zhu, X. Shi, and colleagues on page 1568. The formed MWCNTs are water-dispersible, stable, and have good cytocompatibility and antifouling property. With the low r 2 /r 1 relaxivity ratio and relatively long blood circulation time, the multifunctional MWCNTs are able to be used as a platform for enhanced blood pool and tumor MR imaging.
