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作者: 顾本宏,胡剑麟,李君,欧珠罗布,刘晓强 (上海交通大学医学院附属同仁医院泌尿外科;上海交通大学附属第一人民医院男性健康评估中心;西藏阜康医院妇产儿童院区生殖医学中心;西藏大学高原医学中心;天津医科大学总医院)
出处: 高原科学研究 2021
关键词: 高原;低氧;精子;DFI;生育力;性激素
摘要: 目的:探讨移居高原汉族、世居高原藏族和平原汉族男性精液参数特征,分析高原低氧环境对男性生精功能的影响。方法:从不育门诊收集非无精子症男性3 872例,其中移居汉族1 126例,世居藏族1 094例,平原汉族1 652例;行精液常规、精子形态学、精子运动轨迹分析,并分别对686 606例男性行精子DN ...
作者: 匡祎,张凡,李刚,杜联芳,史秋生 (上海交通大学附属第一人民医院超声科)
出处: 临床超声医学杂志 2021
关键词: 超声检查;造影剂;肾上腺肿瘤,良恶性;鉴别诊断
摘要: 目的探讨超声造影增强特征对肾上腺肿瘤良恶性的鉴别诊断价值。方法选取经病理证实的肾上腺肿瘤患者50例(良性29例,恶性21例),均行常规超声及超声造影检查,重点观察并记录肿瘤的超声造影增强特征,包括:增强时相、增强顺序、增强模式、增强程度,并比较其差异。绘制受试者工作特征(ROC)曲线,计算超声造影增 ...
作者: 江鑫辉,郑丽,杜联芳,吴蓉,李朝军,胡文洁,李凡 (上海市宝山区中西医结合医院超声科;上海交通大学附属第一人民医院超声科)
出处: 临床超声医学杂志 2021
关键词: 超声检查;造影剂;睾丸肿瘤;肿瘤样病变;鉴别诊断
摘要: 目的分析成人睾丸肿瘤和肿瘤样病变的常规超声和超声造影特征,探讨超声造影对其的鉴别诊断价值。方法回顾性分析经手术病理证实的睾丸肿瘤、肿瘤样病变患者(睾丸肿瘤组26例、肿瘤样病变组14例)的常规超声和超声造影检查资料,比较两种疾病的影像学特征,分析超声造影对其的诊断效能。结果睾丸肿瘤组、肿瘤样病变组的病 ...
作者: 姚晖,袁伟杰 (上海交通大学附属第一人民医院护理部;上海交通大学附属第一人民医院肾内科)
出处: 中国血液净化 2021
摘要: 腹膜透析相关性腹膜炎(peritoneal dialysis associated peritonitis,PDAP)是腹膜透析的主要并发症'(1)'。多杀巴斯德菌[2](pasteurella multocida)为革兰氏阴性杆菌的一种,是常存在于猫狗等家畜和野生动物上呼吸道的正常菌群,人类可通过 ...
作者: 韩明丽1,史秋生2,陈红燕1,朱慧1,杜联芳2,王栋华1 (1 复旦大学附属闵行医院上海市闵行区中心医院超声科; 2 上海交通大学附属第一人民医院超声科)
出处: 临床超声医学杂志 2021
关键词: 超声检查;造影剂;混合瘤;Warthin瘤;涎腺
摘要: 目的总结涎腺混合瘤与Warthin瘤的超声造影特征,分析二者的差异。方法回顾性分析我院经手术病理证实的17个涎腺混合瘤和16个Warthin瘤的超声造影特征。结果混合瘤超声造影表现以同进(76.5%)、向心性(64.7%)、不均匀性(76.5%)、低增强(70.6%)为主,增强后边界多清晰(88.2 ...
作者: Miao Yu,Zhi-xiao Fang,Wei-wei Wang,Ying Zhang,Zhi-lei Bu,Meng Liu,Xin-hua Xiao,Zi-lu Zhang,Xing-ming Zhang,Yang Cao,Ying-ying Wang,Hu Lei,Han-zhang Xu,Yun-zhao Wu,Wei Liu,Ying-li Wu (Shanghai General Hospital;Hongqiao International Institute of Medicine;Department of Hematology;Department of Transfusion Medicine;Department of Hematology)
出处: 中国药理学报(英文版) 2021
关键词: AML;Wu-5;crenolanib;USP10;FLT3-ITD;AMPKα;Compound;C;METFORMIN
摘要: The kinase FLT3 internal tandem duplication(FLT3-ITD)is related to poor clinical outcomes of acute myeloid leukemia(AML).FLT3 inhibitors have provided ...
作者: YAO Yan,LIU Hua Min,FENG Xia,LI Dong,ZHOU Yong,ZHANG Zhi Hui (Department of Cardiology,Beijing Anzhen Hospital,Capital Medical University;Department of Epidemiology,School of Public Health,Southern Medical University;School of Public Health,Shandong First Medical University & Shandong Academy of Medical Sciences;Clinical Research Institute,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine;Department of Cardiology,the Third Xiangya Hospital of Central South University)
出处: 生物医学与环境科学(英文版) 2021
摘要: Pregnancy is always associated with several important physiological changes in women,including sex hormone levels,glycolipid metabolism,and oxidative ...
作者: 李小强1,李英凤1,郁敏1,邓静静1,孙静1,宋梦园1,唐裕丹1,聂志文2,杜光烨3 (1 上海市第一人民医院宝山分院病理科; 2 上海市第一人民医院宝山分院检验科; 3 上海交通大学医学院附属第九人民医院病理科)
出处: 诊断病理学杂志 2021 第28卷 第1期 P9-13
关键词: 白血病;B前淋巴细胞;脾脏组织学特点;临床病理分析;R-EPOCH方案
摘要: 目的探讨1例以自发性脾破裂的B细胞前淋巴细胞性白血病(B-PLL)的临床病理特征,进行鉴别诊断、治疗和预后评估。方法回顾性分析1例上海市第一人民医院宝山分院以自发性脾脏破裂的B-PLL大体形态和镜下特点、免疫表型、细胞遗传学及分子生物学特征,与外周血涂片、骨髓涂片和骨髓活检结果相互印证,并复习相关文 ...
作者: Bing-rong Li,Shi-yun Shao,Long Yuan,Ru Jia,Jian Sun,Qing Ji,Hua Sui,Li-hong Zhou,Yi Zhang,Hui Liu,Qi Li,Yan Wang,Bi-meng Zhang (Department of Acupuncture and Moxibustion,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine;Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function,Fudan University;Academy of Integrative Medicine,Shanghai University of Traditional Chinese Medicine,Department of Medical Oncology & Cancer Institute of Integrative Medicine,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine)
出处: Journal of Integrative Medicine 2021 第19卷 第2期 P144-157
关键词: Chemotherapy;Intestinal;mucositis;Moxibustion;Rats;Microbiome;NLRP3
摘要: Objective:The present study investigated how mild moxibustion treatment affects the intestinal Microbiome and expression of NLRP3-related immune facto ...
作者: Fang-fang Li,Yu-lai Liang,Xiao-shuai Han,Ya-na Guan,Jian Chen,Ping Wu,Xian-xian Zhao,Qing Jing (Department of Cardiology,Shanghai General Hospital,School of Medicine,Shanghai JiaoTong University,Hongkou District,Shanghai 200080,China;Key Laboratory of Stem Cell Biology,Shanghai Jiao Tong University School of Medicine(SJTUSM)&Shanghai Institutes for Biological Sciences(SIBS),Chinese Academy of Sciences(CAS),Shanghai 200031,China;CAS Key Laboratory of Tissue Microenvironment and Tumor,Shanghai Institutes for Biological Sciences,University of Chinese Academy of Sciences,Chinese Academy of Sciences(CAS),Shanghai 200031,China;Key Laboratory of Stem Cell Biology,Shanghai Jiao Tong University School of Medicine(SJTUSM)&Shanghai Institutes for Biological Sciences(SIBS),Chinese Academy of Sciences(CAS),Shanghai 200031,China;National Facility for Protein Science,Shanghai 201210,China;Department of Cardiology,Changhai Hospital,Shanghai 200433,China;Key Laboratory of Stem Cell Biology,Shanghai Jiao Tong University School of Medicine(SJTUSM)&Shanghai Institutes for Biological Sciences(SIBS),Chinese Academy of Sciences(CAS),Shanghai 200031,China;CAS Key Laboratory of Tissue Microenvironment and Tumor,Shanghai Institutes for Biological Sciences,University of Chinese Academy of Sciences,Chinese Academy of Sciences(CAS),Shanghai 200031,China)
出处: 中国药理学报(英文版) 2021 第42卷 第3期 P414-421
关键词: purinergic;signaling;P2y12;primitive;hematopoiesis;erythropoiesis;Gata1;Zebrafish
摘要: In the past two decades,purinergic signaling has emerged as a key regulator of hematopoiesis in physiological and pathological conditions.ADP receptor ...
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