作者： Ying, X.-J.;Dong, P.;Shen, B.;Wang, J.;Wang, S.;Wang, G. （Department of Otolaryngology-Head and Neck Surgery, Shanghai Jiao Tong University, Shanghai First People\'s Hospital, Shanghai 200080, China）

出处： JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 2011 Vol.137 No.11 P1661-1667

关键词： Laryngeal carcinoma;Meta-analysis;NAT2;Polymorphism;Risk;Susceptibility

摘要： N-acetyltransferase 2 (NAT2) plays an important role in the metabolism of various potential carcinogens, which can be subdivided into rapid and slow a ...

作者： Jin H.;Yang X.;Liu K.;Gu Q.;Xu X. （Department of Ophthalmology, Shanghai Jiaotong University, Shanghai First People\'s Hospital, No. 100 Haining Road, Shanghai 200080, China）

出处： FEBS Letters 2011 Vol.585 No.21 P3457-3464

关键词： Inflammation;Lipopolysaccharide;NF-κB;Peptide;Thrombomodulin;Uveitis

摘要： Thrombomodulin (TM) is a single-transmembrane glycoprotein receptor for thrombin, which is best known as a cofactor for thrombin-mediated activation o ...

作者： Li, Kang-an;Zhang, Rui-ming;Zhang, Feng;Zhao, Jing-long;Li, Yu-jie;Wang, Xi-fu;Zheng, Lin-feng;Hu, Yun-sheng;Zhang, Gui-xiang （a Department of Radiology, Shanghai First People\'s Hospital, Medical College, Shanghai Jiaotong University, Shanghai 200080, China; b Department of Radiology, Weifang Yidu Center Hospital, Qingzhou, Shandong Province 262500, China）

出处： MAGNETIC RESONANCE IMAGING 2011 Vol.29 No.8 P1101-1109

关键词： CSF;DCE-MRI;ELISA;Metastasis;VEGF;VX2

摘要： Objective: The objective was to analyze the correlation of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with vascular endothelial gr ...

作者： Chen, Y.-H.;Xu, X.;Sheng, M.-J.;Zheng, Z.;Gu, Q. （a Department of Ophthalmology, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai, China; b Department of Ophthalmology, Shanghai Tenth People\'s Hospital, Tongji University, Shanghai, China）

出处： Molecular Vision 2011 Vol.17 No.38-40 P332-340

关键词： ANGIOTENSIN-CONVERTING ENZYME;NITRIC-OXIDE;GROWTH-FACTOR;DIABETIC COMPLICATIONS;ESSENTIAL-HYPERTENSION;SUPEROXIDE-PRODUCTION;OXIDATIVE STRESS;IN-VIVO;ADMA;MECHANISM

摘要： Purpose: Asymmetric dimethylarginine (ADMA), an endogenous competitive inhibitor of nitric oxide synthase, is associated with impaired endothelial dys ...

作者： Zong, L.;Qu, Y.;Luo, X.;Zhu, Z.Y.;Zhang, S.;Su, Z.;Shan, J.C.;Gao, X.P.;Lu, L.G. （a Department of Gastroenterology, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai, China; b National-recognized Enterprise Technology Center, Chengdu Kanghong Pharmaceutical Group, Chengdu, Sichuan Province, China）

出处： JOURNAL OF DIGESTIVE DISEASES 2011 Vol.12 No.4 P295-301

关键词： Choleretic effect;Cholesterol 7α-hydroxylase;Farnesoid X receptor;Peppermint oil

摘要： OBJECTIVE: To investigate the choleretic effect and molecular mechanisms of action of peppermint oil (PO), the main component of Danshu capsules (Sich ...

作者： Cai X.;Xue P.;Gu M.;Hu J.;Gu H.;Yang H.;Wang L. （Department of Oncology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai 200080, China Department of Otolaryngology, Shanghai North City Hospital, Shanghai 200435, China）

出处： Chinese-German Journal of Clinical Oncology 2011 Vol.10 No.4 P235-239

关键词： creatinine clearance (Ccr);Cystatin C (Cys C);neoplasms;urinary micro-albumin (UMA)

摘要： Objective: Chemotherapy drugs such as platinum may cause damage to the renal function, creatinine clearance (Ccr), as a \'golden standard\' indicator ...

作者： Wen, Yu-Gang;Wang, Quan;Zhou, Chong-Zhi （a Department of General Surgery, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China; b Department of General Surgery, Ningxia Medical University, Affiliated Hospital, Yinchuan, Ningxia, China; c Department of Pathology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai, China）

出处： JOURNAL OF SURGICAL ONCOLOGY 2011 Vol.104 No.5 P516-524

关键词： differentially expressed gene;gastric carcinoma;Kallikrein-related peptidase 11;microarray;prognosis

摘要： Background and Objectives: It is important to identify and validate the differentially expressed genes in gastric cancer to screen diagnostic and/or p ...

作者： Chen, Y.-M.;Huang, X.-M.;Thompson, R.;Zhao, Y.-B. （a Department of Neurology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100 Haining Road, Shanghai 200080, China; b Del E Webb Center for Neuroscience, Aging and Stem Cell Research, Sanford-Burnham Medical Research Institute, La Jolla, CA, United States）

出处： JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 2011 Vol.39 No.5 P1946-1953

关键词： Efficacy;Escitalopram;Geriatric Depression;Randomized Controlled Trial;Safety;Selective Serotonin Reuptake Inhibitor (SSRI)

摘要： This study investigated the psychological characteristics and clinical features of 55 patients with geriatric depression, and evaluated the efficacy a ...

作者： Shen, C.;Hao, S.G.;Zhao, C.X.;Zhu, J.;Wang, C. （a Department of Haematology, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, 85 Wujin Road, Shanghai 200080, China; b Department of Haematology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China）

出处： JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 2011 Vol.39 No.3 P740-747

关键词： Acute Promyelocytic Leukaemia;Antitumour Immunity;Dendritic Cells;Exosomes;Vaccines

摘要： Exosomes are a family of bioactive vesicles and play important roles in antigen presentation. A recent phase I clinical trial with an exosome vaccine ...

作者： Wen Zeng;Rong Wan;Yuehuan Zheng;Shree Ram Singh;Yiyong Wei; （Department of Orthopaedics, Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China Department of Orthopaedics, Shanghai First People\'s Hospital, Shanghai Jiaotong University, Shanghai 200080, China Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD 21702, United States）

出处： Cancer Letters 2011 Vol.313 No.2 P129-136

关键词： Hypoxia;Hypoxia inducible factors;Bone tumor;Bone metastasis;Stem cells;Osteosarcoma

摘要： Normal oxygen level is critical for niches that together with other components of the niche play vital role in regulating stem or tumor cells behavior ...