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作者： Li, Jia;Lin, Li-hui;Wang, Juan;Peng, Xia;Liu, Ya-nan;Xiao, Jun-hua;Zhou, Yu-xun;Li, Li （1 Department of Laboratory Medicine, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai China 2 Institute of Biological Sciences and Biotechnology, Donghua University, Shanghai China）
出处： Analytical & Bioanalytical Chemistry 2013 Vol.405 No.4 P1353-1360
关键词： Fluorescent universal primers;Gene expression profiling;IL-4/IL-13 pathway;Multiplex competitive RT-PCR;Real-time PCR
摘要： We established a novel gene expression analysis platform, Multiplex Competitive RT-PCR Using Fluorescent Universal Primers (MCF-PCR), to study multi-g ...
作者： Tingwen Weng;Devine, Erin E;Hongming Xu;Zhisong Yan;Pin Dong （1 Department of Cardiology, Huadong Hospital, Fudan University, Shanghai 200040, People\'s Republic of China 2 Department of Surgery-Division of Otolaryngology- Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA 3 Department of Otolaryngology- Head and Neck Surgery, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, 100th Haining Road, Shanghai 200080, People\'s Republic of China 4 Tongzhou Hospital, Department of Otolaryngology, Nantong, Jiangsu 226300, People\'s Republic of China 5 Department of Otolaryngology- Head and Neck Surgery, Shanghai First People\'s Hospital, Shanghai Jiao Tong University, Shanghai 200080, People\'s Republic of China）
出处： Lipids in Health & Disease 2013 Vol.12 No.1 P1-6
关键词： Cholesterol;Low Density Lipoprotein Cholesterol;Sudden Hearing Loss;Triglycerides
摘要： Background: Pathological levels of blood lipids could be one of the causes of sudden sensorineural hearing loss (SSNHL). The objective of this manuscr ...
作者： Chen, Dawei;Fan, Junwei;Guo, Feng;Qin, Shengying;Wang, Zhaowen;Peng, Zhihai （1 1 Department of General Surgery, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China 2 2 Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Bio-X Institutes, Ministry of Education, Shanghai Jiao Tong University; Shanghai Genomepilot Institutes for Genomics and Human Health, Shanghai, China）
出处： PLoS ONE 2013 Vol.8 No.8 P1-5
关键词： Biochemistry;Biology;Clinical genetics;Clinical immunology;Cytokines;Drug metabolism;Drugs and devices;Genetic association studies;Genetic polymorphism;Genetics;Human genetics;Immune system;Immunologic subspecialties;Medicine;Metabolism;Personalized medicine;Pharmacogenetics;Pharmacokinetics;Population genetics;Research Article;Transplantation
摘要： Background: Tacrolimus is the first-line immunosuppressant after organ transplantation. It is mainly metabolized by cytochrome P450, family 3, subfami ...
作者： Zhi Zhang;Guang Chu;Rui-Xing Yin （1 Department of Cardiology, Shanghai First People\'s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, People\'s Republic of China 2 Department of Cardiology, Institute of Cardiovascular Diseases, The First Affiliated Hospital, Guangxi Medical University, Nanning 530021, Guangxi, People\'s Republic of China）
出处： Lipids in Health & Disease 2013 Vol.12 No.1 P1-10
摘要： Background: The apolipoprotein M (APOM) T-778C gene polymorphism has been associated with serum lipid levels and the risk of coronary artery disease ( ...
作者： Bin Hu;Xiaohui Tian;Jie Sun;Xiangjun Meng （1 Department of Gastroenterology, Shanghai First People\'s Hospital, School of Medicine, Shanghai Jiaotong University, 100 Haining Road, Shanghai 200080, China 2 Department of Gastroenterology, Shanghai Sixth People\'s Hospital, School of Medicine, Shanghai Jiaotong University, 600 Yishan Road, Shanghai 200233, China）
出处： International Journal of Molecular Sciences 2013 Vol.14 No.12 P23559-23580
关键词： biomarkers;detection;diagnosis;hepatocellular carcinoma
摘要： The clinical value of Serum alpha-fetoprotein (AFP) to detect early hepatocellular carcinoma (HCC) has been questioned due to its low sensitivity and ...
作者： Zhu, Hong;Qian, Jin;Wang, Wenqiu;Yan, Quan;Xu, Ying;Jiang, Yuan;Zhang, Lei;Lu, Fengqing;Hu, Weiting;Zhang, Xi;Wang, Fenghua;Sun, Xiaodong （1 1 Department of Ophthalmology, Shanghai First People’s Hospital, School of Medicine, Shanghai JiaoTong University, Eye Research Institute of Shanghai JiaoTong University, Shanghai, China 2 2 Department of Ophthalmology, No.3 People’s Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China 3 3 Eye Research Institute of Shanghai JiaoTong University, Shanghai, China 4 4 Shanghai Key Laboratory of Fundus Disease, Shanghai, China）
出处： PLoS ONE 2013 Vol.8 No.3 P1-7
关键词： Apoptotic signaling;Apoptotic signaling cascade;Biology;Gene expression;Genetics;Genetics and Genomics;Medicine;Molecular Biology;Molecular cell biology;Ophthalmology;Research Article;Retinal disorders;Signal transduction;Signaling cascades;Signaling in cellular processes
摘要： Background: Apoptosis of photoreceptors plays a critical role in the vision loss caused by retinal detachment (RD). Pharmacologic inhibition of photor ...
作者： Chen, Lei;Lu, Jing;Zhang, Jian;Feng, Kai-Rui;Zheng, Ming-Yue;Cai, Yu-Dong （1 2 College of Information Engineering, Shanghai Maritime University, Shanghai, China 2 3 Drug Discovery and Design Center (DDDC), Shanghai Institute of Materia Medica, Shanghai, China 3 4 Department of Ophthalmology, Shanghai First People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China 4 5 Simcyp Limited, Blades Enterprise Centre, Sheffield, United Kingdom 5 1 Institute of Systems Biology, Shanghai University, Shanghai, China）
出处： PLoS ONE 2013 Vol.8 No.2 P1-9
关键词： Applied chemistry;Biochemistry;Biology;Biotechnology;Chemical properties;Chemistry;Drug discovery;Drug information;Drug interactions;Drugs and devices;Medicine;Pharmacology;Predictive toxicology;Research Article;Toxicology
摘要： Toxicity is a major contributor to high attrition rates of new chemical entities in drug discoveries. In this study, an order-classifier was built to ...
作者： Shen, Xiao-yong;Lu, Fan-zhen;Wu, Yun;Zhao, Li-ting;Lin, Zhi-feng （1 1 Department of Thoracic Surgery, The Huadong Hospital, Shanghai Fudan University, Shanghai, China 2 2 Department of Thoracic Surgery, Shanghai First Peoples\' Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China）
出处： PLoS ONE 2013 Vol.8 No.8 P1-7
关键词： Biology;Cancer treatment;Cancers and neoplasms;Chemotherapy and drug treatment;Clinical genetics;Clinical research design;Diagnostic medicine;Epidemiology;Genetic polymorphism;Genetics;Lung and intrathoracic tumors;Medicine;Meta-analyses;Non-small cell lung cancer;Oncology;Population genetics;Research Article;Systematic reviews
摘要： Introduction: X-ray repair cross-complementing protein 3 (XRCC3) is an essential gene involved in the double-strand break repair pathway. Published ev ...
作者： Bao, Wei;Qiu, Haifeng;Yang, Tingting;Luo, Xin;Zhang, Huijuan;Wan, Xiaoping （1 1 Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 2 Department of Obstetrics and Gynecology, Shanghai First People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China 3 3 Department of the Centre of Research Laboratory, International Peace Maternity and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China 4 4 Department of Pathology, International Peace Maternity and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China）
出处： PLoS ONE 2013 Vol.8 No.7 P1-17
关键词： Antiapoptotic signaling;Apoptotic signaling;Basic cancer research;Biology;Cadherins;Cancer risk factors;Cancers and neoplasms;Cell adhesion;Cell death;Endometrial carcinoma;Gynecologic cancers;Gynecological tumors;Medicine;Membrane receptor signaling;Metastasis;Molecular cell biology;Obstetrics and gynecology;Oncology;Ovarian cancer;Research Article;Signal transduction;Signaling cascades;Signaling in cellular processes;Signaling pathways;Tyrosine kinase signaling cascade
摘要： Mechanisms governing the metastasis of endometrial carcinoma (EC) are poorly defined. Recent data support a role for the cell surface receptor tyrosin ...
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