作者： Jingxiang Zhang，Xia Sheng，Quanju Ding，Yujun Wang，Jiwei Zhao，Jingfa Zhang^3,4 （¹Department of Ophthalmology, People’s Hospital of Huangdao District；²Department of Urology, People’s Hospital of Huangdao District；³Department of Ophthalmology, Shanghai General Hospital(Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine；⁴National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases）

出处： Neural Regeneration Research 2025

摘要： Subretinal fibrosis is the end-stage sequelae of neovascular age-related macular degeneration. It causes local damage to photoreceptors, retinal pigme ...

作者： Yisheng Chen¹，Zhongcheng Fan²，Zhiwen Luo¹，Xueran Kang³，Renwen Wan¹，Fangqi Li¹，Weiwei Lin⁴，Zhihua Han⁵，Beijie Qi¹，Jinrong Lin¹，Yaying Sun¹，Jiebin Huang，Yuzhen Xu⁷，Shiyi Chen¹ （¹Department of Sport Medicine, Huashan Hospital, Fudan University；²Department of Orthopedic Surgery, Hainan Province Clinical Medical Center, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine；³Department of Basic Medicine,Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University；⁴Department of Neurosurgery, Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University；⁵Department of Orthopedics, Shanghai General Hospital,School of Medicine Shanghai Jiao Tong University；⁶Department of Infectious Diseases, Children’s Hospital of Fudan University, National Children’s Medical Center；⁷Department of Rehabilitation, The Second Affiliated Hospital of Shandong First Medical University）

出处： Neural Regeneration Research 2025

摘要： Recent research has demonstrated the impact of physical activity on the prognosis of glioma patients,with evidence suggesting exercise may reduce mort ...

作者： Xiaoyu Zhang，Yuqi Liu，Fangxia Xu，Chengcheng Zhou，Kaimei Lu，Bin Fang，Lijuan Wang，Lina Huang，Zifeng Xu （Department of Anesthesiology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University；Department of Anesthesiology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University；Shanghai Key Laboratory of Embryo Original Diseases）

出处： Neural Regeneration Research 2025

关键词： dorsal root ganglion；heterogeneous nuclear ribonucleoprotein F；neuropathic pain；protein arginine methyltransferase-6；sensory neurons

摘要： Protein arginine methyltransferase-6 participates in a range of biological functions, particularly RNA processing, transcription, chromatin remodeling ...

作者： 段诣¹，林江涛¹，岳江²，李媛媛¹，廖静涵¹，孙颖¹，汪权¹，段友容¹，李朝军³ （¹State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University；²Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University；³Department of Ultrasound, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University）

出处： Science China(Materials) 2025

摘要： 动脉粥样硬化仍然是全球发病率和死亡率的主要原因,斑块内新生血管形成显著促进了动脉粥样硬化的进展和不稳定性.血管内皮生长因子A (VEGFA)通过诱导内皮细胞增殖和迁移,刺激斑块中异常微血管的生长.色素上皮衍生因子(PEDF)能够高效抑制VEGFA依赖的新生血管形成.本研究介绍了一种由泊洛沙姆407( ...

作者： Xin Shi，Wei-Jun Wang，Ying Fan，Hai-Yun Liu，Hong Wang，Yu-Hui Chen，Ao Rong，Zhi-Feng Wu，Xun Xu，Kun Liu （Department of Ophthalmology, Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases；Shanghai Jieshi Medical Technology Co.Ltd.；Department of Ophthalmology, Tongji Hospital, School of Medicine, Tongji University；Department of Ophthalmology, Wuxi No.2 People’s Hospital (Jiangnan University Medical Center, JUMC)）

出处： International Journal of Ophthalmology 2024

关键词： perfluoro-n-octane；vitreoretinal surgery；intraocular tamponade；ophthalmic surgery；retinal detachment

作者： 李赞¹，吴秋雪^2,3，卫真真¹，阎旻宇³，隋华¹，汤庆丰^1,4 （¹上海市第一人民医院嘉定医院；²南京中医药大学无锡附属医院；³上海中医大学；⁴上海交通大学医学院附属瑞金医院南翔分院）

出处： 现代肿瘤医学 2024

关键词： 左金丸；胃癌；肿瘤耐药；组蛋白乙酰化

摘要： 目的:探讨左金丸逆转胃癌顺铂耐药的作用机制。方法:体外实验采用人胃癌细胞株SGC-7901及人胃癌顺铂耐药细胞株SGC-7901/DDP,CCK-8法检测细胞增殖率；免疫蛋白印迹法和实时荧光定量PCR法（qRT-PCR）检测左金丸干预后各组基因蛋白表达量；同时构建RTKN基因慢病毒载体转染的胃癌细胞 ...

作者： 顾秋云 （上海市第一人民医院）

出处： 祝您健康 2024

作者： 周兴梅，王小琴 （上海市第一人民医院护理部）

出处： 保健与生活 2024

作者： 笃铭丽¹，朱丽²，陈松文¹，方芳¹ （¹上海市第一人民医院；²复旦大学附属中山医院）

出处： 上海护理 2024

关键词： 心脏介入；专科护士；核心能力；问卷；信度；效度

摘要： 目的 对心脏介入专科护士核心能力自评问卷进行信效度检验。方法 应用心脏介入专科护士核心能力自评问卷，于2022年11月，在全国范围内对534名心脏介入专科护士进行测评，并分析问卷的信效度。结果 心脏介入专科护士核心能力自评问卷包括5个维度45个条目。探索性因子分析累计方差贡献率为71.447%，各条 ...

作者： 吴国庆，汪子栋，赵永波，唐银杉，孟泽宇，刘浩天，王忠义，李志刚 （北京中医药大学针灸推拿学院；上海市第一人民医院神经内科；浙江大学医学院附属第二医院中医康复科；黑龙江中医药大学第二临床医学院；黑龙江中医药大学药学院）

出处： 环球中医药 2024

关键词： 针刺；针刺量效关系；针刺量；针刺效；量效关系影响因素；针刺量化；针刺仿真

摘要： 针刺量效关系研究旨在于阐述针刺量与针刺效的核心内涵,明晰针刺量中刺激量与接受量的分类以及不同刺激量的量化和规范方法;进而分析针刺量效关系的影响因素,研究单一因素与综合因素在同一疾病或不同疾病的最佳刺激参数,从而以疾病和穴位为基础探求针刺量效关系的核心规律,以获取针刺量效关系的更优刺激参数,优化疾病的 ...