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作者: Yiming Chen  1, Wenxu Tang  2, Yifan Wang  1   3, Ya Gao  1   3, Jiaqi Hu  2   4, Yixuan Lu  2, Long Meng  5, Hairong Zheng  5, Yi Feng  6, Liming Cheng  3, Wenyong Fan  7, Qian Cheng  8   9   10, Lei Xue  11   12 (Affiliations 1 Institute of Acoustics, School of Physics Science and Engineering, Tongji University, Shanghai, 200092, China. 2 State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Department of Physiology and Neurobiology, School of Life Sciences, Fudan University, Shanghai, 200438, China. 3 Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education, Department of Orthopedics, School of Medicine, Tongji Hospital affiliated to Tongji University, Tongji University, Shanghai, 200065, China. 4 Center for Rehabilitation Medicine, Department of Pain Management, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China. 5 Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. 6 Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China. 7 Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education, Department of Orthopedics, School of Medicine, Tongji Hospital affiliated to Tongji University, Tongji University, Shanghai, 200065, China. wyfan_tju@tongji.edu.cn. 8 Institute of Acoustics, School of Physics Science and Engineering, Tongji University, Shanghai, 200092, China. q.cheng@tongji.edu.cn. 9 Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education, Department of Orthopedics, School of Medicine, Tongji Hospital affiliated to Tongji University, Tongji University, Shanghai, 200065, China. q.cheng@tongji.edu.cn. 10 Frontiers Science Center for Intelligent Autonomous Systems, Shanghai, 201210, China. q.cheng@tongji.edu.cn. 11 State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Department of Physiology and Neurobiology, School of Life Sciences, Fudan University, Shanghai, 200438, China. lxue@fudan.edu.cn. 12 Research Institute of Intelligent Complex Systems, Fudan University, Shanghai, 200433, China. lxue@fudan.edu.cn.)

出处: Neuroscience bulletin 2025

关键词: Calcium Signaling;Neuronal Excitability;Surface Acoustic Wave;Synaptic Transmission;Ultrasound Neuromodulation.

摘要: Ultrasound neuromodulation shows promise for treating neurological disorders, but the underlying mechanisms remain unclear. Here, we developed an inte ...

作者: Shi-Yun Liu  1, Si-Yu Liu, Bang-Min Han, Shu-Jie Xia (Affiliation 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.)

出处: Asian journal of andrology 2025

关键词: acoustic effect;cellular signaling;erectile dysfunction;low-intensity pulsed ultrasound;mechanobiological transduction;tissue repair.

摘要: Low-intensity pulsed ultrasound (LIPUS) is a non-invasive sonodynamic therapy that has been approved by the U.S. Food and Drug Administration for clin ...

作者: Yajing Liu  1   2, Pengcheng Ye  3, Cijun Tang  1, Meiru Jiang  4, Yiru Shen  1, Xiangrui Wang  1, Lei Hou  1   4, Yupeng Zhao  1 (Affiliations 1 Department of Anesthesiology and Critical Care Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China. 2 Jinzhou Medical University, Jinzhou 121001, China. 3 Department of Anesthesiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China. 4 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.)

出处: Acta biochimica et biophysica Sinica 2025

关键词: CDDO-imidazolide;HMGB1;Nrf2;mitophagy;pyroptosis.

摘要: Accumulating evidence suggests that NLRP3-mediated alveolar macrophage (AM) pyroptosis and subsequent high mobility group box protein 1 (HMGB1) secret ...

作者: Cheng-Hao Zheng  1, Wen-Hao Wang, Shi-Yu Ji, Yi-Feng Jing, Bang-Min Han, Shu-Jie Xia, Xing-Jie Wang (Affiliation 1 Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200080, China.)

出处: Asian journal of andrology 2025

关键词: benign prostatic hyperplasia;inflammatory response;postoperative wound repair;type II 5α-reductase;urothelium regeneration.

摘要: Postoperative wound repair after transurethral resection of the prostate (TURP) in benign prostatic hyperplasia (BPH) patients is crucial for reducing ...

作者: Kangzhi Hu  1   2, Zhuang Yu  2, Yuan Yuan  3, Jing Yi  3, Jinbao Li  2, Minmin Zhu  3, Zhipeng Meng  4, Yongliang Liu  1, Dongwei Cao  5 (Affiliations 1 Department of Anesthesiology, The Affiliated Hongqi Hospital, Mudanjiang Medical University, Mudanjiang 157011, China; School of First Clinical Medical College, Mudanjiang Medical University, Mudanjiang 157011, China. 2 Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. 3 Department of Anesthesiology, Shanghai Pudong Hospital; Fudan University Pudong Medical Center, Shanghai 201399, China. 4 Department of Anesthesiology, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou 313000, China. 5 Department of General Practice, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai 201399, China.)

出处: Acta biochimica et biophysica Sinica 2025

关键词: AARS1;ACSL4;Ferroptosis;diabetic nephropathy;lactylation.

摘要: Diabetic nephropathy (DN) is one of the most severe complications associated with diabetes. Recent studies have demonstrated that lactate-mediated his ...

作者: Hao-Wei Bai  1, Na Li  1, Yu-Xiang Zhang  1, Jia-Qiang Luo  1, Ru-Hui Tian  1, Peng Li  1, Yu-Hua Huang  1, Fu-Rong Bai  1, Cun-Zhong Deng  1, Fu-Jun Zhao  1, Ren Mo  2, Ning Chi  2, Yu-Chuan Zhou  3   4, Zheng Li  1, Chen-Cheng Yao  1, Er-Lei Zhi  1 (Affiliations 1 Department of Andrology, The Center for Men's Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China. 2 Department of Urology, Inner Mongolia People's Hospital, Inner Mongolia Urological Institute, Hohhot 010017, China. 3 International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China. 4 Shanghai Key Laboratory of Embryo Original Diseases, Shanghai 200000, China.)

出处: Asian journal of andrology 2025

摘要: Nonobstructive azoospermia (NOA), one of the most severe types of male infertility, etiology often remains unclear in most cases. Therefore, this stud ...

作者: Jiangnan He1;Luyao Ye2;Hannan Xu2;Huanjie Yang3,4;Juan Shen3,5;Menghan Li2;Shijun Weng6;Dongyue Jiao7;Chen Chu1;Qijun Liao3;Haidong Zou1,2;Jianfeng Zhu1;Chenji Wang7CA;Xun Xu1,2CA1Department of Preventative Ophthalmology, Shanghai Eye Diseases Prevention &Treatment Center/Shanghai Eye Hospital, School of Medicine, Tongji University, National Clinical Research Center for Eye Diseases, Shanghai Engineering Research Center of Precise Diagnosis and Treatment of Eye Diseases , China;2Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Clinical Research Center for Eye Diseases, Shanghai Key Clinical Specialty, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine , China;3BGI Research , China;4College of Life Sciences, University of Chinese Academy of Sciences , China;5Institute of Metagenomics, Qingdao-Europe Advanced Institute for Life Sciences , BGI Research , China;6State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University , China;7State Key Laboratory of Genetic Engineering, MOE Engineering Research Center of Gene Technology, Shanghai Engineering Research Center of Industrial Microorganisms, School of Life Sciences, Fudan University , China)

出处: National Science Review 2025

作者: 王国栋 (上海交通大学附属第一人民医院神经内科)

出处: 科学画报 2024

摘要: 失眠的痛苦相信很多人都体验过,快速入睡、一夜安眠对某些人来说似乎已经成了一种奢望。关于失眠,我们需要了解什么?又该如应对呢?什么是失眠失眠通常指对睡眠时间和(或)质量不满足并影响日间社会功能的一种主观体验。失眠表现为入睡困难(入睡时间超过30分钟)、睡眠维持障碍(整夜觉醒次数≥2次、每次>5分钟)、 ...

作者: 胡晶晶1,冯晓云21上海市第一人民医院嘉定分院内分泌科;2上海交通大学医学院附属第一人民医院内分泌科)

出处: 大众医学 2024

摘要: 努力减肥反增重那是一个普通的周三上午,阳光透过诊室的窗户,照在陶女士有些浮肿、焦虑的脸上。不到40岁的她坐在医生对面,双手交握,显得有些紧张。“医生,我这一年来体重增加了不少,怎么减都减不下来。”陶女士用略显低沉的声音说道,带着些许无奈和困惑。医生询问了她的生活和饮食习惯,没有发现特别不健康的地方。

作者: 常燕翔,胡逸凡,武汉忠,陈进,张蕾 (江苏省东台市人民医院影像科;上海交通大学附属第一人民医院放射科)

出处: 中国CT和MRI杂志 2024

关键词: 异位;肾上腺皮质腺瘤

摘要: 异位肾上腺皮质腺瘤是一种罕见的良性肿瘤,多位于后腹膜中轴、肾脏、盆腔、腹股沟区等;影像学表现缺乏特异性,确诊主要依靠术后病理。现报道1例肾脏异位肾上腺皮质腺瘤,并复习相关文献,旨在提高对该病的认识。1病例资料男,67岁,体检B超发现左肾中部近肾门处占位。本次病程中无畏寒、发热,无咳嗽、咳痰;无腹胀、 ...

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