作者： Ji, Xunda;Cheng, Lin;Wei, Fang;Li, Huiming;Wang, Mengyun;Tian, Yuhua;Chen, Xiafang;Wang, Yufei;Wolf, Frank;Li, Chuanyuan;Huang, Qian

出处： INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 2009 Vol.50 No.12 P5544-5551

摘要： PURPOSE. To establish human retinoblastoma (RB) animal models that allow sensitive, noninvasive and continuous monitoring of tumor growth and metastas ...

作者： Ji, Xunda;Zhang, Jufeng;Cheng, Lin;Wei, Fang;Li, Huiming;Liu, Xinjian;Chen, Xiafang;Li, Chuanyuan;Wang, Yufei;Huang, Qian

出处： EXPERIMENTAL EYE RESEARCH 2009 Vol.89 No.2 P193-199

摘要： Oncolytic conditionally replicating adenoviruses (CRAd) can exclusively replicate in and lyse tumor cells and are therefore promising tools in cancer ...

作者： Wang, Feng;Li, Hui-Ming;Wang, Hui-Ping;Ma, Jia-Lie;Chen, Xia-Fang;Wei, Fang;Yi, Miao-Ying;Huang, Qian

出处： EXPERIMENTAL AND THERAPEUTIC MEDICINE 2010 Vol.1 No.5 P899-904

摘要： The growth of solid tumors is highly dependent on the formation of new blood and/or lymph vessels. Furthermore, metastases often disperse via newly fo ...

作者： Liu, Xinjian;Li, Jinjun;Tian, Yuhua;Xu, Ping;Chen, Xiafang;Xie, Kuangchen;Qiu, Zhengjun;Wang, Yufei;Zhang, Dabing;Wolf, Frank;Li, Chuanyuan;Huang, Qian

出处： HUMAN GENE THERAPY 2010 Vol.21 No.2 P157-170

摘要： Pancreatic cancer is the fourth leading cause of cancer-related death in the United States, and even under optimal therapy these patients face a poor ...

作者： Li, Fang;Huang, Qian;Chen, Jiang;Peng, Yuanlin;Roop, Dennis R.;Bedford, Joel S.;Li, Chuan-Yuan

出处： SCIENCE SIGNALING 2010 Vol.3 No.110

摘要： The ability to regenerate damaged tissues is a common characteristic of multicellular organisms. We report a role for apoptotic cell death in promotin ...

作者： Huang, Qian;Li, Fang;Liu, Xinjian;Li, Wenrong;Shi, Wei;Liu, Fei-Fei;O\'Sullivan, Brian;He, Zhimin;Peng, Yuanlin;Tan, Aik-Choon;Zhou, Ling;Shen, Jingping;Han, Gangwen;Wang, Xiao-Jing;Thorburn, Jackie;Thorburn, An

出处： NATURE MEDICINE 2011 Vol.17 No.7 P860-U231

摘要： In cancer treatment, apoptosis is a well-recognized cell death mechanism through which cytotoxic agents kill tumor cells. Here we report that dying tu ...

作者： Cheng, Lin;Wu, Qiulian;Guryanova, Olga A.;Huang, Zhi;Huang, Qian;Rich, Jeremy N.;Bao, Shideng

出处： BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2011 Vol.406 No.4 P643-648

摘要： Glioblastomas (GBMs) are the most lethal and common types of primary brain tumors. The hallmark of GBMs is their highly infiltrative nature. The cellu ...

作者： Wang, Huiping;Wei, Fang;Zhang, Jufeng;Wang, Feng;Li, Huiming;Chen, Xiafang;Xie, Kuangcheng;Wang, Yufei;Li, Chuanyuan;Huang, Qian

出处： TUMOR BIOLOGY 2012 Vol.33 No.4 P1245-1253

摘要： Low gene transfer rate in tumors, high dose-induced acute inflammatory response, and lack of an immunocompetent preclinical animal model to accurately ...

作者： Feng, Ye;Bao, Wenjing;Luo, Yanli;Tian, Ling;Chen, Xiafang;Yi, Miaoying;Xiong, Hui;Huang, Qian

出处： INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 2012 Vol.53 No.11 P6793-6802

摘要： PURPOSE. Currently, choroidal melanoma is chemoresistant and there is no routine adjuvant chemotherapy for it. We investigated whether pigment epithel ...

作者： Zhang, Shenghai;Wu, Jihong;Wu, Xiaobing;Xu, Ping;Tian, Yuhua;Yi, Miaoying;Liu, Xinjian;Dong, Xiaoyan;Wolf, Frank;Li, Chuanyuan;Huang, Qian

出处： INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 2012 Vol.53 No.6 P2675-2684

摘要： PURPOSE. Recombinant adeno-associated viral vector serotype 2 (rAAV2) has been used with success to deliver retina-targeted gene therapeutics in retin ...