发明人:孙晓东,朱鸿,黄海清,胡洁,汪枫桦,闫泉,翟元琦
申请日期:2018.12.13
摘要:本发明提供了一种细菌性角膜炎动物模型及其构建方法和应用,所述构建方法包括以下步骤:S1、麻醉下在实验小鼠的眼球角膜表面划三条平行切口,深度割破角膜上皮层但不超过角膜内皮层,在角膜切口区域滴加1‑10ul携带荧光标记基因的绿脓杆菌悬液,静置后自然复苏;S2、将经步骤S1处理后的实验小鼠每日进行观察角膜 ...
作者:Xu, Rui-hua;Wang, Fenghua;Shi, Jianhua;Feng, Ji Feng;Shen, Lin;Yang, Shujun;Hu, Xi-Chun;Dai, Guanghai;Xu, Nong;Jiang, Yi;Yongqian, Shu;Zhang, Qingyuan;Chen, Ye;Yuan, Xianglin;Lin, Xiaoyan;Ba, Yi;Li, Qi;Li
出处:JOURNAL OF CLINICAL ONCOLOGY 2018
作者:Zhang, Pengfei;Wang, Hong;Luo, Xueting;Liu, Haiyun;Lu, Bing;Li, Tong;Yang, Shiqi;Gu, Qing;Li, Bin;Wang, Fenghua;Sun, Xiaodong
出处:INFLAMMATION 2018
摘要:Arg-1(+)Ym-1(+) M2-type macrophages play essential roles in the development of choroidal neovascularization (CNV). Thus, inhibition of M2-type macroph ...
作者:Dong, Kai;Zhu, Zi-Cheng;Wang, Feng-Hua;Ke, Gren-Jie;Yu, Zhang;Xu, Xun
出处:INTERNATIONAL JOURNAL OF OPHTHALMOLOGY 2014
摘要:AIM: To investigate whether photoreceptor necroptosis induced by z -VAD -FMK (pan caspase inhibitor) was involved the activation of autophagy and whet ...
作者:Yu, Suqin;Fisher, Yale;Mrejen, Sarah;Wang, Fenghua
出处:INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 2014
作者:Lujan, Brandon J.;Rosenfeld, Philip J.;Gregori, Giovanni;Wang, Fenghua;Knighton, Robert W.;Feuer, William J.;Puliafito, Carmen A.
出处:OPHTHALMIC SURGERY LASERS & IMAGING 2009
摘要:BACKGROUND AND OBJECTIVE: To compare images of geographic atrophy (GA) obtained using spectral domain optical coherence tomography (SD-OCT) with image ...
作者:Sun, Xiaodong;Xu, Xun;Wang, Fenghua;Zhang, Xi;Ho, Patrick C. P.;Liu, Haiyang;Qian, Jin;Yu, Zhang;Lu, Hongfen;Xu, Weiqi
出处:OPHTHALMOLOGICA 2008
摘要:Purpose: To investigate the expression of nerve growth factor (NGF) and its receptor TrkA on the retina at different time points after retinal detachm ...
作者:WANG, Feng-hua;SUN, Xiao-dong;ZHANG, Xi;XU, Xun;ZHU, Qi;HUANG, Jian-nan;FAN, Ying;GU, Qing;LIU, Hai-yang
出处:Chinese Medical Journal 2007
关键词:choroidal neovascularization;cell cultivation;pigment epithelium-derived factors.
摘要:Background: Pigment epithelium-derived factor (PEDF) is expressed in several normal organs and identified as an inhibitor of neovascularization. In th ...
作者:Zhu H;Wang FH;Sun XD
出处:Chinese Medical Journal 2013
作者:Song, Minlu;Shen, Mengxi;Zhou, Yanping;Zheng, Kairong;Zhai, Yuanqi;Xiao, Meichun;Wang, Xiaohan;Wang, Fenghua;Sun, Xiaodong
出处:INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 2018